Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Chinese-Specific Speech Imagery Coding Using High-Density ECoG [NA]
A clinical trial update indicates ongoing recruitment for a study on Chinese-specific speech imagery coding using high-density ECoG. The stu…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Effect of Terazosin on ATP Levels in People With Amyotrophic Lateral Sclerosis [EARLY_Phase 1]
An early-phase (Phase 1) clinical trial is assessing whether terazosin alters ATP levels in people with amyotrophic lateral sclerosis, with …
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Expression Profile Study of Macrophages From Patients Affected by ALS or Other Related Motor Impairments
A clinical trial is currently recruiting to study expression profiles of macrophages from patients with amyotrophic lateral sclerosis and re…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers? [NA]
A clinical trial update describes a study evaluating whether video recordings of multidisciplinary ALS clinics can improve quality of life f…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Amisodin in Healthy Adult Subjects With Amyotrophic Lateral Sclerosis [Phase 1]
This Phase 1 trial aims to evaluate the safety, tolerability, and pharmacokinetics of Amisodin in subjects with amyotrophic lateral sclerosi…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Social Cognition in Patients With Amyotrophic Lateral Sclerosis [NA]
The study is evaluating social cognition in patients with amyotrophic lateral sclerosis and is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial [Phase 2, Phase 3]
A multi-arm adaptive randomized Phase 2/3 clinical trial for motor neuron disease/amyotrophic lateral sclerosis is currently recruiting, spo…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS) [Phase 1, Phase 2]
Regeneron has initiated a first-in-human Phase 1/2 trial of ALN-SOD in adults with ALS caused by SOD1 gene mutations; the study is currently…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Digital Speech Markers for Monitoring ALS in Spanish Speakers
This clinical trial investigates digital speech markers to monitor amyotrophic lateral sclerosis in Spanish speakers and is currently not re…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Alleviating Persistent Dyspnea in Amyotrophic Lateral Sclerosis Patients Treated With Non-Invasive Ventilation Through Immersive Virtual Reality [NA]
A clinical trial update notes ongoing recruitment for a study evaluating immersive virtual reality to alleviate persistent dyspnea in amyotr…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Impact of Robotic Glove Use on Quality of Life, Grip Strength and Fine Motor Control in ALS [NA]
Clinical trial update on a robotic glove assessing quality of life, grip strength, and fine motor control in amyotrophic lateral sclerosis; …
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: iBCI Optimization for Veterans With Paralysis [NA]
This document reports a clinical trial update on iBCI optimization for veterans with paralysis. The study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Personalized Antisense Oligonucleotide Therapy for A Single Patient With CHCHD10 ALS (nL18576) [Phase 1, Phase 2]
The document reports a personalized antisense oligonucleotide therapy for a single patient with CHCHD10-related amyotrophic lateral sclerosi…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: FUSION: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS) [Phase 3]
Phase 3 clinical trial to evaluate the efficacy, safety, pharmacokinetics and pharmacodynamics of ION363 in amyotrophic lateral sclerosis wi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Evaluation of the Combined Therapy of EH-301 and N-acetylcysteine Together With Riluzole in Amyotrophic Lateral Sclerosis (ALS) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the combination of EH-301 and N-acetylcysteine with riluzole in amyotrophic lateral sclerosis; currently…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: HEALEY ALS Platform Trial - Regimen I NUZ-001 [Phase 2, Phase 3]
Clinical trial update for the HEALEY ALS Platform Trial Regimen I NUZ-001 in amyotrophic lateral sclerosis, moving through Phase 2/3 and cur…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Inspiratory Muscle Training in Amiotrophyc Lateral Sclerosis [NA]
A clinical trial sponsored by University Ramon Llull is evaluating inspiratory muscle training in people with Amyotrophic Lateral Sclerosis …
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Digital Tools for Assessment of Motor Functions and Falls in ALS
This clinical trial update describes the use of digital tools to assess motor function and fall risk in amyotrophic lateral sclerosis, with …
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Clinical Outcome Assessment for AT & BCI [NA]
Clinical trial update indicating ongoing recruitment for a study evaluating clinical outcome assessments for an assistive technology and bra…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Assessing Perceptual Effects of Interactive Tasks [NA]
A clinical trial update from Penn State University evaluating perceptual effects of interactive tasks in people with amyotrophic lateral scl…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Healey ALS MyMatch Common Screening Protocol
Clinical trial update describing the Healey ALS MyMatch Common Screening Protocol for ALS patients, with the study listed as not yet recruit…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Safety and Tolerability Study of CTx1000 In Participants With Amyotrophic Lateral Sclerosis [Phase 1]
A Phase 1 study evaluating the safety and tolerability of CTx1000 in participants with amyotrophic lateral sclerosis is currently recruiting…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Kamlanoflast In Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
Kamlanoflast is being studied in amyotrophic lateral sclerosis in Phase 1/Phase 2 trials, with the study status not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Intermuscular Coherence as a Biomarker for ALS
This clinical trial entry notes the recruitment status for a study evaluating intermuscular coherence as a biomarker in amyotrophic lateral …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial investigating Usnoflast for treatment efficacy in Amyotrophic lateral sclerosis, with status listed as active but not…