Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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FDA approval · 2014-04-22FDA Approved: ONCASPAR — Supplemental Application (Servier Pharmaceuticals LLC)
The FDA approved a supplemental application for ONCASPAR (pegaspargase) submitted by Servier Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2014-04-16Clinical Trial Update: Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating alemtuzumab in combination chemotherapy for untreated acute lymphoblastic leukemia; completed with results posted…
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Induction Therapy With Cytarabine, High-Dose Mitoxantrone and Dasatinib for Patients With Philadelphia-Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 trial evaluating induction therapy with cytarabine, high-dose mitoxantrone, and dasatinib for Philadelphia chromosome-positive acute…
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: AMD3100 for Sensitizing in Allogeneic Blood or Marrow Transplant for Chemotherapy Resistant Pediatric Acute Leukemia [Phase 1]
Phase 1 study of AMD3100 (plerixafor) as a sensitizing agent in allogeneic blood or marrow transplant for chemotherapy-resistant pediatric a…
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CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: Palifermin in Preventing Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer [NA]
This clinical-trial update reports completion and results posting for palifermin used to prevent chronic graft-versus-host disease in patien…
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CLINICAL_TRIALS research · 2014-03-26Clinical Trial Update: Open-label Clinical Trial to Investigate the Safety and Tolerability of Allogeneic B-cell Concentrates for Immune Reconstitution After Allogeneic Stem Cell Transplantation Measured as Response to a Antedated Single Vaccination [Phase 1, Phase 2]
Open-label Phase 1/2 clinical trial evaluating the safety and tolerability of donor-derived allogeneic B-cell concentrates to support immune…
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CLINICAL_TRIALS trial_result · 2014-03-21Clinical Trial Update: Vaccine Therapy With or Without Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Multiple Myeloma Undergoing Donor Stem Cell Transplant [Phase 1]
Phase 1 trial evaluating vaccine therapy with or without donor lymphocyte infusion in patients with acute myeloid leukemia, acute lymphoblas…
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: A Study of Clofarabine in Japanese Paediatric Patients With Relapsed or Refractory Acute Lymphoblastic Leukaemia [Phase 1]
A Phase 1 study of clofarabine in Japanese pediatric patients with relapsed or refractory acute lymphoblastic leukemia has completed, provid…
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CLINICAL_TRIALS trial_result · 2014-03-18Clinical Trial Update: Chemotherapy, Imatinib Mesylate, and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial updating on a regimen of chemotherapy plus imatinib mesylate and peripheral stem cell transplantation for adults with…
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CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy [Phase 1]
A National Cancer Institute-sponsored Phase 1 trial evaluating sunitinib malate in HIV-positive cancer patients on antiretroviral therapy ha…
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Osteonecroses in Pediatric Patients With ALL
This clinical trial update describes observations of osteonecrosis in pediatric patients with acute lymphoblastic leukemia, associated with …
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CLINICAL_TRIALS other · 2014-03-03Clinical Trial Update: Phase III Study of Vincristine Sulfate Liposome For Injection In Adults With Naïve Acute Lymphoblastic Leukemia [Phase 3]
An update on a Phase 3 clinical trial evaluating vincristine sulfate liposome for injection in adults with previously untreated acute lympho…
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CLINICAL_TRIALS trial_result · 2014-02-28Clinical Trial Update: The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop [NA]
A terminated clinical trial evaluated whether ankle-foot orthoses improve gait efficiency in children with acute lymphoblastic leukemia and …
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 trial comparing combination chemotherapy with or without peripheral stem cell transplant in children with acute lymphoblastic leuk…
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Gemcitabine in Treating Children With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating gemcitabine in children with relapsed or refractory acute lymphoblastic leukemia or acute myeloid leukemia has comp…
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 clinical trial completion evaluating combination chemotherapy for pediatric acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia [Phase 2]
This is an update on a Phase 2 clinical trial evaluating combination chemotherapy with or without donor bone marrow transplantation for infa…
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CLINICAL_TRIALS trial_result · 2014-02-17Clinical Trial Update: Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 clinical trial comparing different combination chemotherapy regimens in infants with acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2014-02-14Clinical Trial Update: Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 2]
This is a Phase 2 trial update from the Children's Oncology Group evaluating intensified induction therapy for infants with newly diagnosed …
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: A Phase II, Open-Label Study of Clofarabine in Paediatric Patients With Refractory/Relapsed Acute Lymphoblastic Leukaemia [Phase 2]
Phase II, open-label study evaluating clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia. The trial …
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: STI 571 (GLIVEC) in the Treatment of Adult Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 trial evaluating imatinib (STI 571/Glivec) in adults with acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2014-02-05Clinical Trial Update: Clofarabine in Adult Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for clofarabine in adult patients with advanced solid tumors and various hematologic conditions; the…
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
A phase 1/2 trial evaluating the combination of clofarabine and cytarabine in children with refractory or relapsed acute myeloid leukemia or…
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FDA approval · 2014-01-30FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) from Takeda Pharmaceuticals America, Inc.
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CLINICAL_TRIALS trial_result · 2014-01-30Clinical Trial Update: Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia
This clinical trial update describes neurobehavioral complications observed in pediatric survivors of acute lymphoblastic leukemia who previ…