Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2014-08-07Clinical Trial Update: Diagnostic Study of Gene Alterations in Children Who Have Been Treated for Relapsed Acute Lymphocytic Leukemia [NA]
An update on a diagnostic study examining gene alterations in children treated for relapsed acute lymphoblastic leukemia.
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FDA approval · 2014-07-30FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA granted approval of a supplemental application for ICLUSIG (ponatinib hydrochloride) from Takeda Pharmaceuticals America, Inc.
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: Combination Chemotherapy in Treating Children With Very High Risk Acute Lymphocytic Leukemia [Phase 2]
This Clinical Trials Update reports the completion of a Phase 2 study evaluating a combination chemotherapy regimen in children with very hi…
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CLINICAL_TRIALS trial_result · 2014-07-25Clinical Trial Update: Combination Chemotherapy in Treating Children With Stage III or Stage IV Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia [Phase 1]
This update describes a Phase 1 trial of a combination chemotherapy regimen in children with advanced Non-Hodgkin lymphoma or acute lymphobl…
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CLINICAL_TRIALS trial_result · 2014-07-25Clinical Trial Update: Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia [Phase 2]
This report summarizes the completion of a Phase 2 clinical trial evaluating combination chemotherapy in children with newly diagnosed acute…
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FDA approval · 2014-07-24FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) submitted by Takeda Pharmaceuticals America, Inc.
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CLINICAL_TRIALS trial_result · 2014-07-24Clinical Trial Update: Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 update on a multi-modal treatment approach for infants with acute lymphoblastic leukemia, combining chemotherapy, bone marrow tran…
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CLINICAL_TRIALS trial_result · 2014-07-17Clinical Trial Update: Entinostat and Clofarabine in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Poor-Risk Acute Lymphoblastic Leukemia or Bilineage/Biphenotypic Leukemia [Phase 1]
Phase 1 clinical trial evaluating entinostat with clofarabine in newly diagnosed, relapsed, or refractory poor-risk acute lymphoblastic leuk…
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CLINICAL_TRIALS research · 2014-07-14Clinical Trial Update: Pharmacogenetic Analysis of Korean Pediatric Patients With Acute Lymphoblastic Leukemia
A completed pharmacogenetic analysis study in Korean pediatric patients with acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2014-07-14Clinical Trial Update: Monoclonal Antibodies in Recurrent or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL) (MARALL) [Phase 1, Phase 2]
This entry outlines a Phase 1/2 clinical trial (MARALL) evaluating monoclonal antibodies for recurrent or refractory B-cell acute lymphoblas…
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: Pegylated Liposomal Doxorubicin Versus Daunorubicin to Treat Acute Lymphoblastic Leukemia: [Phase 3]
Phase 3 clinical trial comparing pegylated liposomal doxorubicin with daunorubicin for acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Low Dose IL-2, Hematopoietic Stem Cell Transplantation, IL2 for GVHD [Phase 2]
Phase 2 trial update evaluating low-dose interleukin-2 in patients undergoing allogeneic hematopoietic stem cell transplantation to address …
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CLINICAL_TRIALS trial_result · 2014-06-25Clinical Trial Update: Safety and Efficacy of Radio-immunotherapy (RIT) for Patients With Relapse or Refractory Acute Lymphoblastic Leukaemia (ALL) B CD22+ [Phase 1, Phase 2]
A clinical trial update examining the safety and efficacy of radio-immunotherapy for relapsed or refractory CD22-positive B-cell acute lymph…
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CLINICAL_TRIALS trial_result · 2014-06-17Clinical Trial Update: Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 study evaluating vorinostat with or without isotretinoin in pediatric patients with recurrent or refractory solid tumors, lymphoma, …
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CLINICAL_TRIALS trial_result · 2014-06-09Clinical Trial Update: CINJALL: Treatment for Children With Acute Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial update for a treatment in children with acute lymphoblastic leukemia. Results were posted after the study completed i…
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CLINICAL_TRIALS trial_result · 2014-05-23Clinical Trial Update: Combination Chemotherapy and Alemtuzumab in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 trial evaluating the combination of chemotherapy with alemtuzumab in relapsed or refractory acute lymphoblastic leukemia was termi…
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CLINICAL_TRIALS trial_result · 2014-05-22Clinical Trial Update: Intensified Post Remission Therapy Containing PEG-Asparaginase [Phase 2]
Phase 2 trial update evaluating intensified post-remission therapy containing pegaspargase for acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia [Phase 4]
This clinical trial update reports a completed Phase 4 study of rituximab plus chemotherapy for CD20-positive adult acute lymphoblastic leuk…
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CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Total-Body Irradiation With or Without Fludarabine Phosphate Followed By Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer [Phase 3]
Phase 3 trial evaluating total-body irradiation with or without fludarabine phosphate followed by donor stem cell transplant in hematologic …
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CLINICAL_TRIALS trial_result · 2014-05-08Clinical Trial Update: Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood [Phase 1, Phase 2]
Phase 1/2 trial evaluating Wilms' Tumor 1 protein vaccine for blood cancers has completed. Results were posted on 2014-05-08.
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 trial evaluating obatoclax mesylate in combination with vincristine, doxorubicin, and dexrazoxane in pediatric patients with relapse…
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CLINICAL_TRIALS trial_result · 2014-04-30Clinical Trial Update: Natural Killer Index From Hematopoietic Stem Cell Graft [NA]
Clinical trial update on the natural killer index derived from hematopoietic stem cell graft. The study is listed as completed and includes …
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CLINICAL_TRIALS research · 2014-04-29Clinical Trial Update: Computerized Intervention for Amelioration of Cognitive Late Effects Among Childhood Cancer Survivors [NA]
Completed clinical trial update on a computer-based intervention to ameliorate cognitive late effects in childhood cancer survivors; the stu…
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CLINICAL_TRIALS trial_result · 2014-04-29Clinical Trial Update: MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia [Phase 1]
Phase 1 study of MK-2206 in pediatric patients with recurrent or refractory solid tumors or leukemias has completed.
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FDA approval · 2014-04-28FDA Approved: MERCAPTOPURINE — Original Application (Nova Laboratories, Ltd)
FDA approved mercaptopurine (Purixan) under its original NDA (NDA205919) for the treatment of acute lymphoblastic leukemia, representing Nov…