Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2014-01-10Clinical Trial Update: Combination Chemotherapy in Treating Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating a combination chemotherapy regimen for adults with newly diagnosed acute lymphoblastic leukemia; the curre…
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CLINICAL_TRIALS withdrawal · 2014-01-06Clinical Trial Update: IPI-145 in Relapsed Refractory Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Clinical trial update notes that the Phase 2 study of idelalisib (IPI-145) in relapsed/refractory acute lymphoblastic leukemia has been with…
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CLINICAL_TRIALS trial_result · 2014-01-03Clinical Trial Update: S0910 Epratuzumab, Cytarabine, and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating epratuzumab with cytarabine and clofarabine in relapsed or refractory acute lymphoblastic leukemia has completed, w…
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CLINICAL_TRIALS trial_result · 2014-01-03Clinical Trial Update: A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy [EARLY_Phase 1]
A Phase 1 study evaluating the safety and tolerability of combining sirolimus with Hyper-CVAD chemotherapy in adults with lymphoid malignanc…
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CLINICAL_TRIALS trial_result · 2014-01-01Clinical Trial Update: A Pediatric Study of a Plerixafor Containing Regimen In Second Allogeneic Stem Cell Transplantation [Phase 1]
A Phase 1 pediatric study evaluating a plerixafor-containing regimen as part of a second allogeneic stem cell transplantation has completed.
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FDA label_change · 2013-12-20FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) from Takeda Pharmaceuticals America, updating the labeling for…
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CLINICAL_TRIALS trial_result · 2013-12-18Clinical Trial Update: Silymarin (Milk Thistle Extract) in Treating Patients With Acute Lymphoblastic Leukemia Who Are Receiving Chemotherapy [Phase 2]
A Phase 2 clinical trial evaluating silymarin (milk thistle extract) in patients with acute lymphoblastic leukemia undergoing chemotherapy h…
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CLINICAL_TRIALS trial_result · 2013-12-16Clinical Trial Update: Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial update on a therapy for pediatric relapsed or refractory acute lymphoblastic leukemia, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Pharmacokinetic Analysis of High Dose Methotrexate in Pediatric Lymphoblastic Malignancies [NA]
A completed clinical trial evaluating the pharmacokinetics of high-dose methotrexate in pediatric lymphoblastic malignancies, providing PK i…
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CLINICAL_TRIALS trial_result · 2013-12-10Clinical Trial Update: A Phase I Study of WT1 Peptides to Induce Anti-Leukemia Immune Responses Following Transplantation [Phase 1]
A Phase I study evaluating WT1 peptide immunotherapy to induce anti-leukemia immune responses after transplantation was terminated.
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CLINICAL_TRIALS trial_result · 2013-12-05Clinical Trial Update: MLN4924 for the Treatment of Acute Myelogenous Leukemia, Myelodysplastic Syndrome, and Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 clinical trial update showing results for MLN4924 (pevonedistat) in acute myeloid leukemia, acute lymphoblastic leukemia, and myelod…
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CLINICAL_TRIALS research · 2013-12-04Clinical Trial Update: Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia [Phase 3]
This document provides a Phase 3 clinical trial update on hormone therapy plus chemotherapy for children with acute lymphoblastic leukemia.
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CLINICAL_TRIALS withdrawal · 2013-12-03Clinical Trial Update: Study of Sirolimus With PEG-Asparaginase in Acute Lymphoblastic Leukemia (ALL) [Phase 1]
A Phase 1 trial evaluating sirolimus with PEG-asparaginase for acute lymphoblastic leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-12-02Clinical Trial Update: Bioequivalence of An Oral Mercaptopurine Suspension 100 Mg / 5 Ml Versus Tablet in Healthy Male Subjects Under Fasting Conditions [Phase 1]
Phase 1 bioequivalence study comparing an oral mercaptopurine suspension (100 mg/5 mL) with the tablet form in healthy male volunteers under…
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: Intraosseous Infusion of Unrelated Cord Blood Grafts [NA]
Clinical trial evaluating intraosseous infusion of unrelated cord blood grafts was terminated; sponsor was Emory University, and it studied …
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Myeloablative Allogeneic Stem Cell Transplantation Using a Naive T-Cell Depleted Peripheral Blood Stem Cell Graft [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating myeloablative allogeneic stem cell transplantation with a naive T-cell depleted peripheral blood graft…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic Stem Cell Transplant Without Related HLA-Match [Phase 2]
Phase 2 trial evaluating pooled unrelated donor umbilical cord blood transplant for hematologic malignancies requiring allogeneic stem cell …
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EMA guidance · 2013-11-22European Medicines Agency recommends changes in use of leukaemia medicine Iclusig (ponatinib) in order to minimise risk of blood clots
EMA recommends changes in how ponatinib (Iclusig) is used to reduce the risk of blood clots in leukemia treatment.
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CLINICAL_TRIALS research · 2013-11-21Clinical Trial Update: Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia [Phase 4]
Phase 4 clinical trial update describing a treatment protocol for children with Philadelphia chromosome-negative high-risk acute lymphoblast…
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CLINICAL_TRIALS trial_result · 2013-11-15Clinical Trial Update: Prevention of Left Ventricular Dysfunction During Chemotherapy [Phase 3]
Phase 3 clinical trial update focusing on preventing left ventricular dysfunction during chemotherapy in patients with hematologic cancers.
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CLINICAL_TRIALS research · 2013-11-15Clinical Trial Update: RFC and MTHFR SNPs & hENT1- dCK Expression as Prognostic Factors in ALL & hENT1- dCK Expression as Prognostic Factors in AML
This clinical trial update investigates whether RFC and MTHFR SNPs and hENT1-dCK expression serve as prognostic factors in acute lymphoblast…
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CLINICAL_TRIALS research · 2013-11-13Clinical Trial Update: A Drug Monitoring Study on PEG-asparaginase Treatment in Children Diagnosed Acute Lymphoblastic Leukaemia
This document reports on a drug monitoring study evaluating PEG-asparaginase in children with acute lymphoblastic leukemia; the current tria…
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EMA safety_alert · 2013-11-08PRAC updates on the risks of serious vascular occlusive events associated with cancer medicine Iclusig
PRAC provides updates on the risk of serious vascular occlusive events with cancer medicine Iclusig (ponatinib), highlighting safety concern…
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CLINICAL_TRIALS trial_result · 2013-11-07Clinical Trial Update: Safety and Efficacy of an Adult Acute Lymphoblastic Leukemia Chemotherapy for Adult Lymphoblastic Lymphoma [Phase 2]
A Phase 2 clinical trial update evaluating safety and efficacy of an adult acute lymphoblastic leukemia chemotherapy regimen for adult lymph…
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CLINICAL_TRIALS trial_result · 2013-11-06Clinical Trial Update: Antithymocyte Globulin and Cyclosporine in Preventing Graft-Versus-Host Disease in Patients Undergoing Chemotherapy With or Without Radiation Therapy Followed By Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia [NA]
Status update on a clinical trial evaluating antithymocyte globulin and cyclosporine to prevent graft-versus-host disease in patients with a…