Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) [Phase 3]
Phase 3 clinical trial comparing single versus double umbilical cord blood transplants in children with high-risk leukemia and myelodysplasi…
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: Photochemotherapy and Graft-versus-leukemia in Acute-leukemia
This clinical trial update reports a completed study from Karolinska University Hospital evaluating photochemotherapy to enhance graft-versu…
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CLINICAL_TRIALS trial_result · 2015-12-10Clinical Trial Update: Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With Radiotherapy
A completed clinical trial update assessing structural brain imaging and cognitive function in adult stem cell transplant recipients treated…
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CLINICAL_TRIALS trial_result · 2015-12-08Clinical Trial Update: Safety Study of ON 013105 in Lymphoma and Acute Lymphoid Leukemia [Phase 1]
Phase 1 safety study of ON 013105 in lymphoma and acute lymphoblastic leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: GTI-2040 in Treating Patients With Relapsed, Refractory, or High-Risk Acute Leukemia, High-Grade Myelodysplastic Syndromes, or Refractory or Blastic Phase Chronic Myelogenous Leukemia [Phase 1]
Completed Phase 1 trial of GTI-2040 in adults with relapsed or high-risk acute leukemias, myelodysplastic syndromes, or refractory/blastic p…
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FDA approval · 2015-12-03FDA Approved: IMATINIB MESYLATE — Original Application (BluePoint Laboratories)
FDA approved the original application for Imatinib Mesylate from BluePoint Laboratories (ANDA078340), authorizing a generic version of the c…
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FDA approval · 2015-12-01FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) submitted by Takeda Pharmaceuticals America, Inc., under NDA 2…
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CLINICAL_TRIALS trial_result · 2015-11-24Clinical Trial Update: A Study Of Panobinostat In Children With Refractory Hematologic Malignancies [Phase 1]
This update reports the completion of a Phase 1 pediatric study evaluating panobinostat in children with refractory hematologic malignancies…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Physical Activity to Modify Sequelae and Quality of Life in Childhood Acute Lymphoblastic Leukemia [NA]
Completed clinical trial evaluating whether structured physical activity can modify long-term sequelae and improve quality of life in childr…
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CLINICAL_TRIALS research · 2015-11-17Clinical Trial Update: Prevalence of Psychocognitive Impairments in Adolescents Surviving Childhood Leukemia : LEA-PsyCog [NA]
This clinical trial update describes LEA-PsyCog, a study investigating the prevalence of psycho-cognitive impairments in adolescents who sur…
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CLINICAL_TRIALS withdrawal · 2015-10-30Clinical Trial Update: Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia [Phase 2]
A Phase 2 study evaluating Nilotinib with combination chemotherapy for newly diagnosed Philadelphia chromosome-positive acute lymphoblastic …
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CLINICAL_TRIALS trial_result · 2015-10-23Clinical Trial Update: Nebulized Amphotericin B Lipid Complex in Invasive Pulmonary Aspergillosis in Paediatric Patients With Acute Leukaemia [Phase 2]
Phase 2 trial evaluating nebulized amphotericin B lipid complex for invasive aspergillosis in pediatric patients with acute leukemia has com…
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: HD-Idarubicin/Etoposide Intensified Conditioning Regimen Allo-HSCT for Adult ALL [Phase 4]
A Phase 4 clinical trial update on an intensified conditioning regimen using high-dose idarubicin and etoposide before allogeneic hematopoie…
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CLINICAL_TRIALS trial_result · 2015-10-06Clinical Trial Update: Transplant-Related Mortality in Patients Undergoing a Peripheral Blood Stem Cell Transplantation or an Umbilical Cord Blood Transplantation
This is an update on a completed trial assessing transplant-related mortality in patients undergoing peripheral blood stem cell transplantat…
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: Resistance to Methotrexate in Patients With Acute Lymphoblastic Leukemia in Relapse or Remission
This completed clinical trial evaluated resistance to methotrexate in patients with acute lymphoblastic leukemia who were in relapse or remi…
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CLINICAL_TRIALS research · 2015-09-29Clinical Trial Update: Genetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory to Chemotherapy [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/Phase 2 study of a genetically engineered lymphocyte therapy for chemotherapy-resistant or refrac…
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit [Phase 2]
Phase 2 clinical trial evaluating hematopoietic stem cell transplantation using a CD34-selected mismatched related donor plus one umbilical …
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Rituximab in Treating Young Patients Who Are Receiving Chemotherapy for B-Cell Non-Hodgkin's Lymphoma or B-Cell Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial of rituximab in young patients receiving chemotherapy for B-cell non-Hodgkin lymphoma or B-cell acute lymphoblastic leukemia h…
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CLINICAL_TRIALS trial_result · 2015-09-16Clinical Trial Update: Moxetumomab Pasudotox (CAT-8015, HA22) in Children With B-lineage Acute Lymphoblastic Leukemia and Minimal Residual Disease Prior to Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2]
This is a Phase 2 clinical trial update reporting termination of a study evaluating moxetumomab pasudotox in pediatric B-lineage acute lymph…
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Clofarabine in Chinese Pediatric Patients With Refractory or Relapsed Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating clofarabine in Chinese pediatric patients with refractory or relapsed acute lymphoblastic leukemia has c…
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial assessing nilotinib in combination with standard chemotherapy for newly diagnosed acute lymphoblastic leukemia. Results have b…
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CLINICAL_TRIALS withdrawal · 2015-08-31Clinical Trial Update: A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid Malignancies [Phase 1]
A Phase I study of an alloreactive cell infusion following transplantation of haplotype cells in patients with myeloid malignancies has been…
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CLINICAL_TRIALS research · 2015-08-27Clinical Trial Update: Motor Proficiency And Physical Activity in Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)
The clinical trial update notes that the study on motor proficiency and physical activity in adult survivors of childhood acute lymphoblasti…
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CLINICAL_TRIALS trial_result · 2015-08-25Clinical Trial Update: MK0457 in Patients With Leukemia (0457-003) [Phase 1]
Phase 1 trial update for MK-0457 (VX-680) in leukemia patients has completed; the study included chronic myeloid leukemia in blast crisis, a…
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CLINICAL_TRIALS trial_result · 2015-08-06Clinical Trial Update: Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial comparing dexamethasone vs prednisone in induction and methotrexate with/without leucovorin in maintenance for newly diagnosed…