Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Response or Resistance to Chemotherapy in Young Patients With Acute Lymphoblastic Leukemia Treated With Methotrexate
This clinical trial update summarizes how young patients with acute lymphoblastic leukemia responded to or developed resistance to methotrex…
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Phase 1 Study of TG02 Citrate in Patients With Advanced Hematological Malignancies [Phase 1]
Phase 1 study evaluating TG02 Citrate in patients with advanced hematologic malignancies has completed, including AML, ALL, blast crisis, MD…
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CLINICAL_TRIALS trial_result · 2016-05-03Clinical Trial Update: Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies [Phase 2]
Phase 2 clinical trial update on mismatched family member donor stem cell transplantation in children and young adults with high-risk hemato…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation [Phase 2]
Phase 2 clinical trial evaluating repeat transplantation for relapsed or refractory hematologic malignancies after prior transplant; the stu…
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EMA approval · 2016-04-29New treatment for rare white blood cell cancer
The EMA announces a new treatment for a rare white blood cell cancer, representing a targeted option for this rare indication.
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CLINICAL_TRIALS trial_result · 2016-04-28Clinical Trial Update: A Pilot Study Investigating the Effects of Acetyl-L-Carnitine and Vincristine-Induced Neuropathy in Pediatric Patients With ALL [Phase 2]
Phase 2 pilot trial in pediatric acute lymphoblastic leukemia evaluating acetyl-L-carnitine to mitigate vincristine-induced neuropathy; the …
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Nilotinib Pre and Post Allogeneic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating nilotinib given before and after allogeneic stem cell transplantation in chronic myeloid leukemia and acute lymphob…
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: Belinostat and Bortezomib in Treating Patients With Relapsed or Refractory Acute Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 trial testing belinostat and bortezomib in relapsed or refractory acute leukemias and myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2016-03-24Clinical Trial Update: Allogeneic Stem Cell Transplant With Clofarabine, Ara-C and TBI for AML and ALL [Phase 1, Phase 2]
A phase 1/2 trial evaluating an allogeneic stem cell transplant regimen using clofarabine, cytarabine (Ara-C), and total body irradiation fo…
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies [Phase 2]
Phase 2 trial of Brentuximab Vedotin in CD30-positive non-lymphomatous malignancies has completed and results were posted in 2016. The study…
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CLINICAL_TRIALS research · 2016-03-04Clinical Trial Update: Pharmacokinetics of Asparaginase and Antibody Formation in Interfant-06
This update reports on the pharmacokinetics of asparaginase and the development of anti-asparaginase antibodies in the Interfant-06 leukemia…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Safety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety and efficacy of POL6326 for mobilization and transplant in hematologic malignancies has completed…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer [Phase 2]
Phase 2 trial update of Basiliximab to prevent graft-versus-host disease after nonmyeloablative allogeneic transplantation in blood cancers;…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: The Effect of Deferasirox on Response Rate of Acute Leukemia Patients Not Treated by Standard Chemotherapy Regimens [Phase 1]
Phase 1 study examining whether deferasirox alters response rate in patients with acute myeloid leukemia or acute lymphoblastic leukemia who…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia [Phase 3]
This completed Phase 3 trial compared different combination chemotherapy regimens in children with acute lymphoblastic leukemia to determine…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Phase 1 Study of Terameprocol (EM-1421) in Patients With Leukemia [Phase 1]
Phase 1 study of Terameprocol (EM-1421) in leukemia was terminated; no efficacy results were reported in this update.
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Biomarkers to Classify Young Patients With Acute Lymphoblastic Leukemia (ALL) and Remission Induction Therapy in Young Patients With B-Precursor ALL [NA]
This clinical trial update discusses biomarkers used to classify young patients with acute lymphoblastic leukemia and their remission-induct…
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CLINICAL_TRIALS research · 2016-02-17Clinical Trial Update: A 5 Day Course of Fludarabine and Cytarabine Followed by Full Intensity Allogeneic Stem Cell Transplantation (FA5-Bucy) in Treating Patients With High-risk, Recurrent or Refractory Acute Leukemia and Advanced Myelodysplastic Syndrome
A clinical trial update describes a five-day course of fludarabine and cytarabine followed by full-intensity allogeneic stem cell transplant…
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CLINICAL_TRIALS withdrawal · 2016-02-17Clinical Trial Update: Study of Dasatinib in Imatinib Resistant or Intolerant Subjects With Chronic or Advanced Phase CML or Philadelphia Chromosome Positive ALL [Phase 2, Phase 3]
The trial studying dasatinib in imatinib-resistant or intolerant chronic myeloid leukemia or Philadelphia chromosome‑positive acute lymphobl…
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CLINICAL_TRIALS trial_result · 2016-01-27Clinical Trial Update: A Pharmacokinetic (PK) Study of Nilotinib in Pediatric Patients With Philadelphia Chromosome-positive (Ph+) Chronic Myelogenous Leukemia (CML) or Acute Lymphoblastic Leukemia (ALL) [Phase 1]
Phase 1 pharmacokinetic study of nilotinib in pediatric patients with Philadelphia chromosome–positive CML or ALL; study completed with resu…
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: PACE CALL: Weight Loss Study for Childhood Leukemia Survivors [NA]
The PACE CALL weight loss study for childhood acute lymphoblastic leukemia survivors has completed. The update does not provide specific res…
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: LAL-BR/2001: Study Treatment to Low Risk ALL [Phase 4]
Phase 4 trial LAL-BR/2001 assessing treatment for low-risk acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2015-12-31Clinical Trial Update: Safety and Efficacy Study of Donor Natural Killer Cells Given After Haploidentical Hematopoietic Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 study assessed safety and efficacy of donor natural killer cells given after haploidentical hematopoietic cell transplantation i…
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CLINICAL_TRIALS trial_result · 2015-12-28Clinical Trial Update: Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia [NA]
Clinical trial results for umbilical cord blood transplantation in pediatric patients with high-risk leukemia and myelodysplasia; the study …
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: A Study of the Safety and Preliminary Efficacy of Oral Midostaurin (PKC412) in Relapsed or Refractory Pediatric Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports safety and preliminary efficacy data for oral midostaurin (PKC412) in relapsed or refractory pedia…