Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-08-06Clinical Trial Update: Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or Testes [NA]
This clinical trial update notes the completion and posting of results for a study evaluating combination chemotherapy and radiation therapy…
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy [Phase 2, Phase 3]
This update summarizes a Phase 2/Phase 3 study of StemEx for high-risk hematologic malignancies after myeloablative therapy, focusing on eff…
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CLINICAL_TRIALS trial_result · 2015-07-09Clinical Trial Update: Nilotinib With Chemotherapy for the Treatment of Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
This clinical trial update notes the termination of a Phase 1/2 study evaluating nilotinib in combination with chemotherapy for Philadelphia…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery [Phase 1]
Phase 1 study sponsored by the National Cancer Institute evaluating dasatinib in patients with metastatic or unresectable solid tumors and l…
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CLINICAL_TRIALS trial_result · 2015-06-29Clinical Trial Update: Methotrexate, Vincristine, Pegylated L-Asparaginase and Dexamethasone (MOAD) in Acute Lymphoblastic Leukemia (ALL) Salvage [Phase 2]
Phase 2 results for the MOAD regimen (methotrexate, vincristine, pegylated L-asparaginase and dexamethasone) in salvage therapy for acute ly…
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Allogeneic Stem Cell Transplantation in Children and Adolescents With Acute Lymphoblastic Leukaemia [Phase 3]
Phase 3 clinical trial evaluating allogeneic stem cell transplantation in children and adolescents with acute lymphoblastic leukemia; the st…
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Study of Infusion of Blood Cells (Lymphocytes) to Stimulate the Immune System to Fight Leukemia/Lymphoma [Phase 2]
A Phase 2 trial evaluating infusion of blood cells (lymphocytes) to stimulate the immune system for fighting leukemia/lymphoma was terminate…
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CLINICAL_TRIALS research · 2015-06-26Clinical Trial Update: ALL-SCT BFM International- HSCT in Children and Adolescents With ALL [Phase 3]
Phase 3 clinical trial update for hematopoietic stem cell transplantation in children and adolescents with acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, and biological activity of oral clioquinol in patients with relapsed or refracto…
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CLINICAL_TRIALS research · 2015-06-22Clinical Trial Update: Vincristine PK and PD in the AYA Population Compared to Younger Children
A clinical trial update examining vincristine pharmacokinetics and pharmacodynamics in adolescents and young adults compared with younger ch…
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: Study of Farnesyl Protein Transferase Inhibitor (FPTI) in Patients With Leukemia (Study P00701) [Phase 1, Phase 2]
Phase 1/2 trial of a Farnesyl Protein Transferase Inhibitor in leukemia and myelodysplastic syndromes has completed, sponsored by Merck Shar…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of OPB-51602 in Patients With Hematologic Malignancies [Phase 1]
Phase I trial results are reported for OPB-51602 in patients with hematologic malignancies including multiple myeloma, non-Hodgkin lymphoma,…
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CLINICAL_TRIALS trial_result · 2015-05-15Clinical Trial Update: Bortezomib, Vorinostat and Dexamethasone for Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 trial evaluating bortezomib, vorinostat, and dexamethasone for relapsed/refractory acute lymphoblastic leukemia has been terminated …
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Chronic Graft-versus-host Disease (cGvHD) Prophylaxis With or Without ATG Prior to Stem Cell Transplantation (SCT) From HLA-identical Siblings in Patients With Acute Leukemia [Phase 3]
Phase 3 trial evaluating prophylaxis for chronic graft-versus-host disease using anti-thymocyte globulin (ATG) prior to stem cell transplant…
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CLINICAL_TRIALS withdrawal · 2015-05-13Clinical Trial Update: An Open-Label, Single-Arm, Multicenter Pharmacokinetic Study of Intramuscular Erwinaze® (Asparaginase Erwinia Chrysanthemi)/Erwinase® (Crisantaspase) [Phase 2]
Phase 2 open-label PK study of intramuscular Erwinaze (asparaginase Erwinia chrysanthemi) / Erwinase (crisantaspase) for acute lymphoblastic…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Allogeneic Stem Cell Transplantation (SCT) With Treosulfan, VP-16 and Cyclophosphamid for Patients With Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 clinical trial evaluating allogeneic stem cell transplantation using treosulfan, etoposide (VP-16), and cyclophosphamide for acute l…
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: PROCEDYTE: Depocyte® Administration (Liposomal Cytarabine) as Prophylaxis of Neuromeningeal Infiltration in Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 trial of Depocyte (liposomal cytarabine) for prophylaxis of neuromeningeal infiltration in acute lymphoblastic leukemia has been t…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias [Phase 1]
Phase 1 study of TH-302 (evofosfamide), a hypoxia-activated prodrug, in patients with advanced leukemias has been completed, with evaluation…
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CLINICAL_TRIALS research · 2015-05-07Clinical Trial Update: Study of the Physical and Emotional Needs of Parents Caring for Children Receiving Chemotherapy for Acute Lymphoblastic Leukemia [NA]
A study update describing the physical and emotional needs of parents caring for children undergoing chemotherapy for acute lymphoblastic le…
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CLINICAL_TRIALS trial_result · 2015-04-30Clinical Trial Update: A Safety and Tolerability Study of Clofarabine, Etoposide, Cyclophosphamide, PEG-asparaginase, and Vincristine in Pediatric Acute Lymphoblastic Leukemia (ALL) [Phase 1]
Phase 1 safety and tolerability study of a multi-agent regimen (clofarabine, etoposide, cyclophosphamide, peg-asparaginase, and vincristine)…
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CLINICAL_TRIALS trial_result · 2015-04-28Clinical Trial Update: Sorafenib in Treating Patients With Refractory or Relapsed Acute Leukemia, Myelodysplastic Syndromes, or Blastic Phase Chronic Myelogenous Leukemia [Phase 1]
This Phase 1 trial update reports on the use of sorafenib in patients with refractory or relapsed acute leukemia, myelodysplastic syndromes,…
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: Tipifarnib and Bortezomib in Treating Patients With Acute Leukemia or Chronic Myelogenous Leukemia in Blast Phase [Phase 1]
This update summarizes a Phase 1 study of tipifarnib and bortezomib in patients with acute leukemia and blast-phase chronic myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2015-04-06Clinical Trial Update: Prevention of Invasive Fungal Infections (IFIs) in Subjects Receiving Chemotherapy for Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial evaluating prevention of invasive fungal infections in patients with acute lymphoblastic leukemia undergoing chemotherapy has …
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL) [Phase 1, Phase 2]
The study reports Phase 1 and Phase 2 results for chemoimmunotherapy including epratuzumab in children with relapsed acute lymphoblastic leu…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Investigation of Clofarabine in Acute Leukemias [Phase 2]
Phase 2 trial of clofarabine in acute myeloid leukemia, acute lymphoblastic leukemia, and chronic myelogenous leukemia has completed enrollm…