Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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FDA approval · 2016-08-04FDA Approved: IMATINIB MESYLATE — Original Application (Teva Pharmaceuticals USA, Inc.)
FDA approval of Teva's Imatinib Mesylate Original Application under ANDA204285 for a generic Imatinib product.
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignancies [Phase 1]
This Phase 1 clinical trial update reports on an anti-CD19 CAR-T cell therapy being tested in patients with B cell malignancies, including c…
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: Sequential Intensive Chemotherapy Followed by RIC for Refractory and Relapse ALL [Phase 2]
A Phase 2 clinical trial is evaluating sequential intensive chemotherapy followed by reduced-intensity conditioning for patients with refrac…
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: Study Evaluating the Efficacy and Safety of PCAR-019 in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma [Phase 1, Phase 2]
Clinical trial update for PCAR-019 evaluating efficacy and safety in CD19-positive relapsed or refractory leukemia and lymphoma across Phase…
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CLINICAL_TRIALS trial_result · 2016-07-25Clinical Trial Update: Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus [Phase 2]
Phase 2 study evaluating unrelated cord blood transplantation using tacrolimus and sirolimus for hematologic malignancies has completed.
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders [Phase 2]
A Phase 2 trial testing nonmyeloablative allogeneic stem cell transplantation from HLA-matched unrelated donors for multiple hematologic dis…
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CLINICAL_TRIALS withdrawal · 2016-07-14Clinical Trial Update: Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies [Phase 2]
A Phase 2 clinical trial evaluating single or double donor umbilical cord blood transplant for high-risk hematologic malignancies has been w…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Biomarkers in DNA Samples From Patients With High-Risk Acute Lymphoblastic Leukemia
This completed trial update reports on biomarkers found in DNA samples from patients with high-risk acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2016-07-06Clinical Trial Update: Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia [Phase 2]
A completed Phase 2 clinical trial assessing combination chemotherapy in patients with untreated acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2016-07-04Clinical Trial Update: Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia [Phase 2]
A Phase 2 trial of a combination chemotherapy regimen for non-Hodgkin lymphoma and acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Chemotherapy for Leukemia [Phase 1, Phase 2]
A completed Phase 1/2 safety study evaluating CLT-008 (human myeloid progenitor cells) in patients with various leukemias after chemotherapy…
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: Treatment of Acute Lymphoblastic Leukemia (ALL) in Younger Adults [Phase 3]
Phase 3 clinical trial update on treatment for acute lymphoblastic leukemia in younger adults has completed. The snippet does not report the…
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CLINICAL_TRIALS trial_result · 2016-06-16Clinical Trial Update: Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)
A Stanford-sponsored clinical trial evaluating allogeneic transplantation for acute and chronic leukemias has been terminated.
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FDA approval · 2016-06-16FDA Approved: LEVOLEUCOVORIN — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved Hikma Pharmaceuticals USA Inc.'s levoleucovorin as an Original Application generic; levoleucovorin is used in cancer regimens w…
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CLINICAL_TRIALS research · 2016-06-14Clinical Trial Update: Carfilzomib in Patients With Relapsed Acute Myeloid or Acute Lymphoblastic Leukemia [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating carfilzomib in patients with relapsed acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2016-06-07Clinical Trial Update: Risk of Psychopathology and Neurocognitive Impairment in Leukemia Survivors
This clinical trial update reports on the risk of psychopathology and neurocognitive impairment among survivors of acute lymphoblastic leuke…
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Study of mAb 216 With Chemotherapy for Treatment of Pediatric Relapsed or Refractory B-progenitor Acute Lymphoblastic Leukemia [Phase 1]
This notice reports the termination of a Phase 1 clinical trial studying monoclonal antibody 216 in combination with chemotherapy for childr…
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FDA label_change · 2016-06-02FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) from Takeda Pharmaceuticals America, Inc. The approval updates…
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Genetic Test in Detecting Minimal Residual Disease in Samples From Younger Patients Registered on the COG-AALL08B1 Trial
This clinical trial update describes a genetic test used to detect minimal residual disease in samples from younger patients enrolled in the…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Genetic Test To Identify Previously Undetectable Minimal Residual Disease in Cell Samples From Younger Patients With Acute Lymphoblastic Leukemia
A completed clinical trial update evaluating a genetic test to detect minimal residual disease in cell samples from children with acute lymp…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying Dexamethasone and Prednisone Sensitivity in Samples From Younger Patients With High-Risk B-Cell Precursor Acute Lymphoblastic Leukemia
A clinical trial evaluated sensitivity to dexamethasone and prednisone in samples from younger patients with high-risk B-cell precursor acut…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia
Completed clinical trial update studying gene analyses in samples from younger patients with relapsed childhood acute lymphoblastic leukemia…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Studying DNA in Blood and Bone Marrow Samples From Young Patients With Acute Lymphoblastic Leukemia
This clinical trial update describes a study examining DNA in blood and bone marrow samples from young patients with acute lymphoblastic leu…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Laboratory Study of Lymphoblasts in Young Patients With High-Risk Acute Lymphoblastic Leukemia
A completed clinical trial registry entry describing a laboratory study of lymphoblasts in young patients with high-risk acute lymphoblastic…
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Identifying Risk Factors for Bone Tissue Death in Young Patients With Acute Lymphoblastic Leukemia Treated on Clinical Trial CCG-1882
A clinical trial update analyzes factors associated with bone tissue death (osteonecrosis) among young patients with acute lymphoblastic leu…