Acute Lymphoblastic Leukemia
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant [Phase 1]
Phase 1 clinical trial evaluating CMV-MVA Triplex Vaccine to enhance CMV-specific immunity and prevent CMV viremia in patients undergoing ha…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Pediatric-Inspired Regimen Combined With Venetoclax and Immunotherapy for Adult Ph-Negative Acute Lymphoblastic Leukemia [NA]
This clinical trial update describes a study combining a pediatric-inspired regimen with venetoclax and immunotherapy for adults with Philad…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia [Phase 3]
This document describes a Phase 3 treatment study protocol for acute lymphoblastic leukemia in participants aged 0-45 years, currently recru…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia [Phase 1]
Phase 1 study to identify the highest dose of Revumenib (SNDX-5613) after hematopoietic stem cell transplant in children with acute lymphobl…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Little NIRVANA for Pediatric Pain and Anxiety [NA]
A pediatric pain and procedural anxiety trial titled 'Little NIRVANA' is currently enrolling by invitation at Nationwide Children's Hospital…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy
This clinical trial update describes an ongoing prospective evaluation of delayed effects after pediatric CAR T cell therapy in acute lympho…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia [Phase 2]
A Phase 2 clinical trial evaluating CD19-directed CAR T cell therapy for pediatric, adolescent, and young adult patients with CD19-positive …
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Safety and Feasibility of TMLI as Conditioning Regimen in Allogeneic Hematopoietic Stem-cell Transplantation [NA]
This clinical trial evaluated the safety and feasibility of Total Marrow and Lymphoid Irradiation (TMLI) as conditioning before allogeneic h…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide [Phase 1]
Phase 1 clinical trial update evaluating expanded/activated gamma delta T-cell infusion after hematopoietic stem cell transplantation with p…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: MB-CART19.1 in Relapsed/Refractory Acute Lymphoblastic Leukemia [NA]
Clinical trial update for MB-CART19.1 in relapsed/refractory acute lymphoblastic leukemia, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Immunotherapy Combined With Auto-HSCT and CD22/CD19 CAR-T Sandwich Strategy for B-ALL [Phase 2]
Phase 2 clinical trial evaluating a combination of immunotherapy with autologous hematopoietic stem cell transplant and CD22/CD19 CAR-T cell…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Clinical Study of Universal CD19 CAR-γδ T Cell Infusion in the Treatment of Relapsed/Refractory Acute B Lymphoblastic Leukemia [Phase 1]
Phase 1 clinical study evaluating universal CD19 CAR-γδ T cell infusion for relapsed/refractory acute lymphoblastic leukemia (B-cell lineage…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: MedSupport Intervention to Identify and Address Barriers to Pediatric Medication Adherence [NA]
Clinical trial update describes the MedSupport Intervention to identify and address barriers to pediatric medication adherence in acute lymp…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Full-Course Immunotherapy Consolidation for Unfit or Fit B-ALL Who Decline Chemotherapy [Phase 2]
Phase 2 clinical trial update for consolidation immunotherapy in acute lymphoblastic leukemia patients who are unfit or decline chemotherapy…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Enzomenib (DSP-5336) for acute leukemias, including acute myeloid leukemia and acute lymphoblastic leu…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Study of Obecabtagene Autoleucel in People With B-cell Acute Lymphoblastic Leukemia [Phase 2]
This document announces a Phase 2 clinical trial evaluating Obecabtagene Autoleucel for B-cell acute lymphoblastic leukemia, with recruitmen…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Hospital Based Continuous Patient Monitoring System [NA]
This entry reports a hospital-based continuous patient monitoring system trial that is not yet recruiting, covering trauma, post-appendectom…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial [Phase 3]
This entry details a Phase 3 extension study of Venetoclax for patients who completed prior Venetoclax trials. The study is currently active…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Study of Cell-free DNA in Children and Adolescents With Acute Lymphoblastic Leukemia
This clinical trial update describes a study evaluating cell-free DNA in children and adolescents with acute lymphoblastic leukemia. The stu…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: HEM-SURVIVE: Structuralized Follow-up for Childhood Hematological Malignancy Survivors
HEM-SURVIVE is a structured follow-up study for childhood survivors of hematologic malignancies; the trial is currently NOT_YET_RECRUITING a…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Assessment of Chimerism and Relapse Post Bone Marrow/Hematopoietic Cell Transplant (HCT) Using AlloHeme Test
A clinical trial update evaluating the AlloHeme test for assessing chimerism and detecting relapse after bone marrow/hematopoietic cell tran…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation [Phase 1, Phase 2]
A phase 1/2 trial evaluating Revumenib in relapsed/refractory leukemias including MLL/KMT2A rearrangements or NPM1 mutations; currently recr…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) [Phase 1, Phase 2]
A Phase 1/2 clinical trial at the University of Chicago evaluating LP-118 with ponatinib, vincristine, and dexamethasone for relapsed/refrac…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 trial evaluating total marrow and lymphoid irradiation with fludarabine and melphalan before donor stem cell transplant for high-r…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 trial evaluating HLA-mismatched unrelated donor hematopoietic cell transplantation with post-transplantation cyclophosphamide is act…