Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Anti-Covid-19 Vaccine in Children With Acute Leukemia and Their Siblings [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing an anti-COVID-19 vaccine in children with acute leukemia and their siblings; study completed.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Study of the Infusion of ARI-0001 Cells in Patients With CD19 + Acute Lymphoid Leukemia Resistant or Refractory to Therapy [Phase 2]
Phase 2 study of ARI-0001 CAR-T cells for CD19-positive acute lymphoblastic leukemia. The trial is currently active but not recruiting.
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CLINICAL_TRIALS withdrawal · 2024-06-21Clinical Trial Update: HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies [Phase 1, Phase 2]
Clinical trial update notes the withdrawal of a Phase 1/2 study evaluating decitabine with venetoclax and navitoclax for relapsed or refract…
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Validity and Reliability of the Inflammatory Arthritis Facilitators and Barriers to Physical Activity Questionnaire
This clinical trial update describes a planned study to validate the Inflammatory Arthritis Facilitators and Barriers to Physical Activity Q…
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Mercaptopurine Therapeutic Drug Monitoring to Optimize the Maintenance Phase of Childhood ALL
This clinical trial update describes a study evaluating therapeutic drug monitoring of mercaptopurine to optimize the maintenance phase in c…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Dose Adjusted EPOCH Regimen in Combination With Ofatumumab or Rituximab in Treating Patients With Newly Diagnosed or Relapsed or Refractory Burkitt Lymphoma or Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating Dose Adjusted EPOCH combined with either ofatumumab or rituximab in newly diagnosed or relapsed/refractory Burkitt …
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CLINICAL_TRIALS research · 2024-06-06Clinical Trial Update: CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL [Phase 1]
Phase 1 study of CD19/CD22 CAR-T cells in adults with relapsed or refractory acute lymphoblastic leukemia or B-cell lymphoma, currently recr…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant [Phase 1, Phase 2]
This clinical trial update examines using CD34+ malignant stem cell selection for patients receiving allogeneic stem cell transplants in Pha…
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FDA approval · 2024-06-03FDA Approved: METHOTREXATE — Original Application (Alembic Pharmaceuticals Inc.)
FDA approved Alembic Pharmaceuticals' original application for methotrexate, authorizing the generic version of the drug.
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Blinatumomab Maintenance After Allo-HSCT [Phase 2]
A Phase 2 clinical trial is evaluating blinatumomab as maintenance therapy after allogeneic hematopoietic stem cell transplantation in patie…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Combination of an Anti-PD1 Antibody With Tisagenlecleucel Reinfusion in Children, Adolescents and Young Adults With Acute Lymphoblastic Leukemia After Loss of Persistence [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating reinfusion of tisagenlecleucel in combination with an anti-PD1 antibody for children, adolescents, and…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: The Patient Cohort of the National Center for Precision Medicine in Leukemia
This clinical trial update describes the patient cohort for the National Center for Precision Medicine in Leukemia and notes that patient re…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Nutritional Status in Children With ALL in Guatemala
A completed clinical trial assessing nutritional status in children with acute lymphoblastic leukemia in Guatemala, sponsored by Columbia Un…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: CD19 CAR-T Cells With CRS Suppression Technology for r/r CD19+ Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
This update describes a Phase 1/2 clinical trial of CD19 CAR-T cells with CRS suppression technology for relapsed/refractory CD19-positive a…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy [NA]
A completed clinical trial evaluating the feasibility of a digital health coaching program for individuals after CAR T-cell therapy.
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Determining the Mechanisms of Loss of CAR T Cell Persistence
A University College London trial is investigating the mechanisms behind loss of CAR T cell persistence in acute lymphoblastic leukemia and …
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Symptom Patterns and Life With Longer Term COVID-19 in Children and Young People (SPLaT-19 Cohort & Qualitative Study)
Completed observational study examining symptom patterns and long-term impact of COVID-19 in children and young people, including a subset w…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Edinburgh and Lothian Virus Intervention Study in Kids [NA]
The Edinburgh and Lothian Virus Intervention Study in Kids has completed; it evaluated a viral intervention for upper respiratory tract infe…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Study Protocol: Study on Incidence and Risk Factors of Mold Infections in Children During Leukemia Treatment
This document describes a protocol for a study to determine the incidence of mold infections in children undergoing leukemia treatment and i…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC) [Phase 2]
Phase 2 clinical trial comparing reduced-dose total body irradiation with cyclophosphamide, fludarabine, and melphalan as reduced-intensity …
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: CD19-BAFF CAR-T Cells Therapy for Patients With Relapsed / Refractory B-cell ALL and B-cell NHL [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating CD19-BAFF CAR-T cells for relapsed or refractory B-cell acute lymphoblastic leukemia and B-cell n…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Probiotic in Infant Growth, Allergy and Immunity Study [NA]
This clinical trial update indicates a probiotic study in healthy infants and infants with acute lymphoblastic leukemia is not yet recruitin…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe) [Phase 2]
This Phase 2 clinical trial update reports on conditioning with benadamustine, fludarabine, and busulfan (FluBuBe) for recipients of haploid…
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CLINICAL_TRIALS research · 2024-05-06Clinical Trial Update: The Effect of Kangaroo Care After Cardiac Surgery [NA]
An ongoing clinical trial sponsored by Istinye University is evaluating the effects of kangaroo care after cardiac surgery in infants with a…
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CLINICAL_TRIALS other · 2024-05-06Clinical Trial Update: Expanded Access to Navitoclax
Expanded access program for Navitoclax sponsored by AbbVie for myelofibrosis, acute lymphoblastic leukemia, and lymphoblastic lymphoma is no…