Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: HCL Single Arm Pilot Study in Treatment of Hyperglycemia of Pediatric ALL [EARLY_Phase 1]
A single-arm early-phase pilot trial in high-risk pediatric acute lymphoblastic leukemia investigating treatment of hyperglycemia was termin…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers [Phase 2]
A Phase 2 clinical trial update on haploidentical stem cell transplantation for multiple hematologic cancers, with the study status reported…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Family-Based Behavioral Treatment for Childhood Survivors of Acute Lymphoblastic Leukemia [NA]
A clinical trial evaluating family-based behavioral treatment for childhood survivors of acute lymphoblastic leukemia has been terminated.
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CLINICAL_TRIALS research · 2024-05-01Clinical Trial Update: Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research [EARLY_Phase 1]
A Phase 1 clinical trial update evaluating the safety and preliminary efficacy of metabolically armed CD19 CAR-T cells (Meta10-19) in relaps…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Care Pathway and Associated Costs of Patients Treated With CAR T-cells Based on SNDS Data
This study updates care pathways and costs for patients treated with CAR T-cell therapies using SNDS data.
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients [Phase 2]
A Phase 2 study evaluating azacitidine, venetoclax, and flumatinib in newly diagnosed Ph-positive acute leukemia and CML-AP/BP; the trial ha…
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FDA approval · 2024-04-15FDA Approved: RYLAZE — Supplemental Application (Jazz Pharmaceuticals, Inc.)
The FDA approved a supplemental application for RYLAZE (asparaginase Erwinia chrysanthemi recombinant) submitted by Jazz Pharmaceuticals, In…
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: A Pilot RCT of the PRISM Intervention for AYAs With Cancer [Phase 2]
pilot randomized Phase 2 trial evaluating the PRISM intervention for adolescents and young adults with cancer, completed.
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor ALL [Phase 1]
Phase 1 trial evaluating blinatumomab with AMG 404 in adults with relapsed or refractory B cell precursor acute lymphoblastic leukemia has c…
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CLINICAL_TRIALS trial_result · 2024-04-04Clinical Trial Update: Blinatumomab Followed by High-dose Chemotherapy for Ph-negative Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 trial evaluating blinatumomab followed by high-dose chemotherapy for Ph-negative acute lymphoblastic leukemia (ALL) in adults; study…
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer [Phase 2]
Phase 2 study evaluating a conditioning regimen of fludarabine phosphate, cyclophosphamide, and total body irradiation followed by donor ste…
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CLINICAL_TRIALS trial_result · 2024-04-01Clinical Trial Update: Blinatumomab for Relapsed Acute B Lymphoblastic Leukemia After Transplantation [Phase 4]
A Phase 4 clinical trial update evaluating blinatumomab for relapsed acute B-lymphoblastic leukemia after transplantation.
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: Asparaginase Encapsulated in Erythrocytes for Patients With ALL and Hypersensitivity to PEG-asparaginase [Phase 2]
Phase 2 trial of erythrocyte-encapsulated asparaginase for Acute Lymphoblastic Leukemia patients with hypersensitivity to PEG-asparaginase h…
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FDA approval · 2024-03-13FDA Approved: ONCASPAR — Supplemental Application (Servier Pharmaceuticals LLC)
FDA approved a supplemental application for ONCASPAR (pegaspargase) submitted by Servier Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children [Phase 2]
Phase 2 trial exploring selective depletion of CD45RA+ T cells from allogeneic stem cell grafts to prevent GVHD in children has completed wi…
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FDA approval · 2024-03-06FDA Approved: BESPONSA — Supplemental Application (Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.)
The FDA approved a supplemental application for BESPONSA (inotuzumab ozogamicin) submitted by Wyeth Pharmaceuticals LLC, a subsidiary of Pfi…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: GNR-084 Safety and Pharmacological Characteristics in Refractory or Relapse B-cell Precursor ALL [Phase 1, Phase 2]
A clinical trial update reporting safety and pharmacological characteristics of GNR-084 in refractory or relapsed B-precursor acute lymphobl…
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FDA approval · 2024-03-01FDA Approved: GLEEVEC — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for GLEEVEC (imatinib mesylate) submitted by Novartis Pharmaceuticals Corporation. This action confi…
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CLINICAL_TRIALS trial_result · 2024-02-12Clinical Trial Update: Regional Anesthesia for Totally Awake Upper Limb Surgery in PEDiatric Population [Phase 4]
Phase 4 clinical trial update on regional anesthesia for totally awake upper limb surgery in the pediatric population.
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: International Study for Treatment of Standard Risk Childhood Relapsed ALL 2010 [Phase 3]
A phase 3 international study evaluating treatment for standard risk childhood relapsed acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: Acute Concussion and Melatonin [Phase 2]
Phase 2 clinical trial update evaluating melatonin for concussion in pediatric patients, with conditions including mild concussion and brain…
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia. [Phase 1]
Phase 1 trial of clofarabine with low-dose total body irradiation as a preparative regimen for stem cell transplant in leukemia shows comple…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant [Phase 1]
Phase 1 trial evaluating the CMV-MVA Triplex vaccine given to stem cell donors to prevent cytomegalovirus viremia in recipients of allogenei…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy [Phase 2]
Phase 2 clinical trial update for MGTA-456 in high-risk hematologic malignancies; results were posted in 2024 and the study is currently act…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: DS-3201b for Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL) [Phase 1]
Phase 1 trial update for DS-3201b in acute myeloid leukemia and acute lymphocytic leukemia has been terminated with results posted.