Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Haploidentical Donor vs mMUD in Hematological Malignancies [Phase 2, Phase 3]
A Phase 2/3 clinical trial comparing haploidentical donor transplantation to matched unrelated donor transplantation in hematologic malignan…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Study to Assess the Safety of Escalating Doses of AT9283, in Patients With Leukemias [Phase 1, Phase 2]
An early-phase study of escalating doses of AT9283 for various leukemias has been terminated.
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: The clonoSEQ® Watch Registry
Clinical trial update for the clonoSEQ Watch Registry sponsored by Adaptive Biotechnologies; the study status is terminated.
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FDA approval · 2024-07-31FDA Approved: PHYRAGO — Supplemental Application (Cycle Pharmaceuticals Ltd)
The FDA approved a supplemental application for PHYRAGO (dasatinib) from Cycle Pharmaceuticals Ltd, indicating an update to the product's la…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Vitamin A and D Supplementation in Allogeneic HCT [Phase 2]
Phase 2 clinical trial in allogeneic hematopoietic cell transplantation is evaluating vitamin A and vitamin D supplementation, currently rec…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Study of pCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents [Phase 2]
Phase 2 clinical trial investigating pCAR-19B for CD19-positive relapsed/refractory B-cell acute lymphoblastic leukemia in children and adol…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Cytogenetic Studies in Acute Leukemia and Multiple Myeloma
Update on cytogenetic studies in acute leukemia and multiple myeloma; the trial is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: A Study of PD5K3 in Healthy Adult Volunteers [Phase 1]
Phase 1 clinical trial update for PD5K3 in healthy adult volunteers; the study has completed and investigated safety and pharmacokinetics. C…
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: Phase II Study of Post-Transplant Low-Dose Inotuzumab Ozogamicin to Prevent Relapse of Acute Lymphoblastic Leukemia [Phase 2]
A Phase II clinical trial is evaluating low-dose inotuzumab ozogamicin after transplant to prevent relapse in patients with acute lymphoblas…
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR [Phase 1, Phase 2]
A Phase 1/2 clinical trial at University Hospital Heidelberg is evaluating third-generation CD19-directed CAR T cells in relapsed or refract…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: MRD Detection by NGS in Pediatric T-ALL
This clinical trial update describes using next-generation sequencing to detect minimal residual disease in pediatric T-cell acute lymphobla…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: Comparative Quantification of MTX and Its Metabolites Post Glucarpidase
This completed clinical trial evaluated the pharmacokinetics of methotrexate and its metabolites after glucarpidase administration in patien…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: Video-recOrded hospItal dischaRge (VOIR) [NA]
Clinical trial update for the VOIR study (video-recorded hospital discharge) sponsored by Anglia Ruskin University. The study lists acute ly…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: The Measurement of Vital Signs in Children by Lifelight® Software in Comparison to the Standard of Care
The clinical trial evaluates how Lifelight software measures vital signs in pediatric patients compared with standard of care. The study has…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Use of T-allo10 in Hematopoietic Stem Cell Transplantation (HSCT) for Blood Disorders [Phase 1]
Phase 1 trial update on T-allo10 for hematopoietic stem cell transplantation in various blood disorders; the NCT03198234 study sponsored by …
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Everolimus With Multiagent Re-Induction Chemotherapy in Pediatric Patients With ALL [Phase 1]
This Phase 1 trial assesses adding Everolimus to multiagent re-induction chemotherapy in pediatric patients with Acute Lymphoblastic Leukemi…
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Hypertension Intervention to Reduce Osteonecrosis in Children With Acute Lymphoblastic Leukemia/Lymphoma [Phase 2]
Phase 2 trial evaluating whether a hypertension intervention reduces osteonecrosis in children with acute lymphoblastic leukemia or lymphoma…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: the Efficacy and Safety of Total Myeloid Irradiation (TMI) in the Treatment of Adult Acute Lymphoblastic Leukemia
An update on a clinical trial evaluating the efficacy and safety of Total Myeloid Irradiation for adults with acute lymphoblastic leukemia, …
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Haploidentical Stem Cell Transplantation Using Post-Transplant Cyclophosphamide [Phase 2]
Phase 2 haploidentical stem cell transplantation trial using post-transplant cyclophosphamide was terminated.
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FDA approval · 2024-07-09FDA Approved: MERCAPTOPURINE — Supplemental Application (Nova Laboratories, Ltd)
The FDA approved a supplemental application for mercaptopurine (Purixan) by Nova Laboratories, Ltd., updating the product labeling and/or in…
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FDA approval · 2024-07-09FDA Approved: MERCAPTOPURINE — Supplemental Application (Florida Pharmaceutical Products, LLC)
FDA approved a supplemental application for Mercaptopurine submitted by Florida Pharmaceutical Products, LLC.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Effectiveness of an Intervention on Vaccine Hesitancy Among Pediatric Nurses and Pediatricians [NA]
A completed clinical trial evaluating an intervention based on presumptive communication and motivational interviewing to reduce vaccine hes…
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CLINICAL_TRIALS other · 2024-07-03Clinical Trial Update: COVID-19 and Childhood Cancer
Karolinska Institutet reports a clinical trial update indicating a study on COVID-19 and childhood cancer is currently active but not recrui…
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CLINICAL_TRIALS research · 2024-06-28Clinical Trial Update: Combined Immuno-chemotherapy for Patients With B-linear Acute Lymphoblastic Leukemia Diagnosed From 0 to 365 Days of Life (ALL-Baby-2021) [Phase 3]
Phase 3 clinical trial evaluating combined immunotherapy and chemotherapy for infants with acute lymphoblastic leukemia; recruitment is ongo…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: BeFluBu vs FluBuRux Conditioning in Haploidentical HCT [Phase 2]
Phase 2 clinical trial comparing BeFluBu vs FluBuRux conditioning regimens in haploidentical stem cell transplantation is currently recruiti…