Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Use of Integrated Pulmonary Index Monitorisation in Children Undergoing Botulinum Toxin Injection [NA]
This completed clinical trial evaluated integrated pulmonary index monitoring during botulinum toxin injections in children, including those…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Clinical Research of CD19 Targeted CAR-T Cell in Relapsed/ Refractory B-ALL [Phase 1]
Phase 1 clinical trial evaluating CD19-targeted CAR-T cell therapy for relapsed/refractory acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Cardiovascular Function in Acute Leukemia
A completed clinical trial update evaluating cardiovascular function and potential cardiotoxicity in patients with acute leukemia.
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: Cell Therapy with Anti-CD19 CAR-NK Cells in Patients with Relapsed or Resistant B-ALL [Phase 1, Phase 2]
A Phase 1/2 trial evaluating anti-CD19 CAR-NK cell therapy in relapsed or resistant acute lymphoblastic leukemia. The study is currently not…
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: Integrative "Omics" Approaches for Leukemia Target Identification and Matched Therapeutic Intervention [NA]
The study uses integrative 'omics' approaches to identify leukemia targets and matched therapeutic interventions and is currently recruiting…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Applying Pediatric Nursing Excellence Model to Nurses in Orthopedic Surgery Care of Children [NA]
The completed study evaluates applying the Pediatric Nursing Excellence Model to nurses caring for children undergoing orthopedic surgery, f…
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CLINICAL_TRIALS withdrawal · 2024-09-25Clinical Trial Update: Continuous Ambulatory Monitoring to Predict Elevated Risk of Infection in Children With Lymphoblastic Leukemia Undergoing Induction Chemotherapy (CAMPER-ALL)
A clinical trial investigating continuous ambulatory monitoring to predict infection risk in children with Acute Lymphoblastic Leukemia unde…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial evaluating combination chemotherapy with or without blinatumomab in newly diagnosed BCR-ABL-negative B-ALL; status active not …
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial evaluating addition of blinatumomab to standard chemotherapy in newly diagnosed BCR-ABL-negative B-lineage acute lymphoblastic…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Autologous Hematopoietic Stem Cell Transplantation Combined With CD19-CART Treatment of Adult High-risk Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial investigating autologous hematopoietic stem cell transplantation combined with CD19-CAR T-cell therapy for adult high…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Phase I Study of CYC140, a PLK-1 Inhibitor, in Advanced Leukemias or MDS [Phase 1]
Phase I study of CYC140, a PLK-1 inhibitor, in advanced leukemias and myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: CAR T Cells in the Treatment of Refractory and Relapsed CD19+ B Cell Neoplasms [Phase 1]
Phase 1 trial of CD19-targeted CAR T cells for refractory/relapsed CD19-positive B-cell neoplasms (ALL, mantle cell lymphoma, diffuse large …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Blinatumomab Added to Prephase and Consolidation Therapy in Precursor B-acute Lymphoblastic Leukemia in Adults. [Phase 2]
Phase 2 study in adults with precursor B-cell acute lymphoblastic leukemia adds blinatumomab to prephase and consolidation therapy.
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors
A completed clinical trial assessing how habitual physical activity affects bone and metabolic health in pediatric cancer survivors, includi…
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: MGTA-145 + Plerixafor in the Mobilization of HSCs for Allogeneic Transplant in Hematologic Malignancies [Phase 2]
Phase 2 study evaluating MGTA-145 in combination with Plerixafor for mobilizing hematopoietic stem cells for allogeneic transplantation in h…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Assessing Neurophysiological and Cognitive Function in School Children
A completed clinical trial assessing neurophysiological and cognitive function in school-age children with pediatric acute lymphoblastic leu…
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CLINICAL_TRIALS withdrawal · 2024-08-26Clinical Trial Update: Taking POSNA's OrthoKids to the People [NA]
Clinical trial NCT04996745 has been withdrawn; the study involved pediatric forearm fracture and pediatric acute lymphoblastic leukemia unde…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating a combination of post-transplant cyclophosphamide, abatacept, vedolizumab, and baricitinib to prevent graft…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia [EARLY_Phase 1]
A clinical trial is investigating whether levocarnitine can reduce asparaginase-associated hepatotoxicity in patients with acute lymphoblast…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Laser Therapy Effect on Oral Mucositis in Childhood Acute Lymphoblastic Leukemia Patients [NA]
ClinicalTrials.gov update describes a study evaluating laser therapy to reduce oral mucositis in children with acute lymphoblastic leukemia.…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL) [Phase 1]
Phase 1 trial results evaluate palbociclib in combination with chemotherapy for pediatric patients with relapsed acute lymphoblastic leukemi…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of JCAR017 in Pediatric Subjects With Relapsed/Refractory (r/r) B-cell Acute Lymphoblastic Leukemia (B-ALL) and B-cell Non-Hodgkin Lymphoma (B-NHL) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating lisocabtagene maraleucel (JCAR017) in pediatric relapsed/refractory B-cell acute lymphoblastic leukemi…
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CLINICAL_TRIALS withdrawal · 2024-08-14Clinical Trial Update: Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph+ ALL [Phase 2]
A Phase 2 trial evaluating ponatinib plus reduced-intensity chemotherapy as first-line therapy for adults with Philadelphia chromosome-posit…
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CLINICAL_TRIALS research · 2024-08-14Clinical Trial Update: Glucose Intolerance and Diabetes Related to Treatment With Steroids and PEG- Asparaginase in Children and Adolescents With ALL and Lymphoma
A clinical trial update evaluating glucose intolerance and diabetes related to steroid and PEG-asparaginase treatment in children and adoles…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia [Phase 1]
Phase 1 study evaluating revumenib in combination with chemotherapy for relapsed/refractory acute leukemias has completed.