Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies [Phase 1]
Phase 1 clinical trial studying tagraxofusp in pediatric patients with CD123-expressing hematologic malignancies is currently recruiting, sp…
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CLINICAL_TRIALS withdrawal · 2024-12-05Clinical Trial Update: Preemptive Infusion of Donor Lymphocytes Depleted of TCR + T Cells + CD19+ B Cells Following ASCT [Phase 1]
A Phase 1 trial evaluating a preemptive infusion of donor lymphocytes depleted of TCR+ T cells and CD19+ B cells after autologous stem cell …
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Study of Sequential CAR-T Cell Treating Leukemia Children [Phase 2]
A Phase 2 trial of sequential CAR-T cell therapy for pediatric acute lymphoblastic leukemia has been terminated.
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FDA approval · 2024-12-03FDA Approved: PHYRAGO — Supplemental Application (Cycle Pharmaceuticals Ltd)
FDA approved a supplemental application for PHYRAGO (dasatinib) submitted by Cycle Pharmaceuticals Ltd.
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia [Phase 4]
Phase 4 clinical trial updating on the minimum effective concentration and volume of ropivacaine for sacral plexus anesthesia in pediatric p…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort
The QUALITY cohort study (Quebec Adipose and Lifestyle Investigation in Youth) is active but not recruiting, examining obesity, Type 2 diabe…
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FDA approval · 2024-11-22FDA Approved: IMKELDI — Original Application (Shorla Oncology Inc.,)
FDA approved IMKELDI (imatinib oral) under an original NDA from Shorla Oncology, authorizing a new imatinib product for several cancers incl…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Comparison of Computertomography Scan, Electrical Impedance Tomography, and Ultrasound of the Lung in Infants
A clinical trial comparing computed tomography, electrical impedance tomography, and ultrasound for assessing lung status in infants is curr…
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CLINICAL_TRIALS other · 2024-11-20Clinical Trial Update: Study of TBI-1501 for Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Clinical trial update for TBI-1501 in relapsed or refractory acute lymphoblastic leukemia (adult), currently in Phase 1/Phase 2 and not recr…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: WT1 Vaccine Treatment of Patients in Remission From Acute Myeloid Leukemia (AML) or Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 trial evaluating the WT1 vaccine in patients in remission from acute myeloid leukemia or acute lymphoblastic leukemia has completed …
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FDA approval · 2024-11-07FDA Approved: DANZITEN — Original Application (Azurity Pharmaceuticals, Inc.)
FDA approved the Original Application for DANZITEN (nilotinib) from Azurity Pharmaceuticals, establishing a branded nilotinib product for Ph…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Singapore's Health Outcomes After Critical Illness in Kids
This completed study at KK Women's and Children's Hospital in Singapore evaluates health outcomes in children— including those with pediatri…
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CLINICAL_TRIALS research · 2024-11-05Clinical Trial Update: Systemic Inflammation Response Index and C-Reactive Protein to Albumin Ratio in Acute Lymphoblastic Leukemia
This clinical trial update describes a study evaluating the systemic inflammation response index and the C-reactive protein to albumin ratio…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial update on a Triplex CMV vaccine designed to prevent CMV infection in patients undergoing hematopoietic stem cell tran…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating CD19-specific CAR-engineered autologous T cells for relapsed or refractory CD19-positive acute lymphoblastic leuk…
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FDA approval · 2024-10-29FDA Approved: CYCLOPHOSPHAMIDE — Original Application (Nexus Pharmaceuticals, LLC)
FDA approved Nexus Pharmaceuticals, LLC to market a generic cyclophosphamide product under Original Application ANDA216783.
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Effects of Home-Based Exercise Program in Children After Acute Lymphoblastic Leukemia [NA]
This clinical trial update reports on a completed study evaluating a home-based exercise program in children after acute lymphoblastic leuke…
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Safety and Efficacy of PRG-2302 for Refractory or Relapsed B-cell Acute Lymphoblastic Leukemia Disease. [EARLY_Phase 1]
An early-phase trial evaluating the safety and efficacy of PRG-2302 for refractory or relapsed B-cell acute lymphoblastic leukemia, currentl…
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FDA approval · 2024-10-23FDA Approved: JYLAMVO — Supplemental Application (SHORLA ONCOLOGY INC.)
The FDA approved a supplemental application for JYLAMVO (methotrexate) filed by SHORLA ONCOLOGY INC.
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Effectiveness of Developed Interactive Play Mat In Pediatric Physical Therapy [NA]
This document reports on an ongoing clinical trial evaluating the effectiveness of an interactive play mat in pediatric physical therapy for…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Ponatinib in Adult Ph+ ALL Patients With MRD Positivity or Hematological Relapse [Phase 2]
Phase 2 study evaluating ponatinib in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia, including MRD-positive and …
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT) [Phase 2]
Phase 2 trial of a cytomegalovirus vaccine for donors and recipients undergoing allogeneic hematopoietic cell transplantation has completed,…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Reduced-Dose Chemo Followed by 14 Days of Blinatumomab for Newly Diagnosed Adult B-ALL Patients: a Multicenter Study
A multicenter study is evaluating reduced-dose chemotherapy followed by 14 days of blinatumomab for newly diagnosed adult B-lymphoblastic le…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: CD34 Selected Allogeneic HCT w/ Myeloablative Conditioning Plus CD8+ Memory TCell Infusion in MDS, AL and CML [Phase 2]
Phase 2 clinical trial evaluating CD34-selected allogeneic hematopoietic stem cell transplantation with myeloablative conditioning plus CD8+…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia [Phase 1]
A Phase 1 study evaluating the safety and potential efficacy of combining blinatumomab with nivolumab, with or without ipilimumab, in patien…