Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Feasibility/Acceptability of Attentional-Control Training in Survivors [NA]
A clinical trial is evaluating the feasibility and acceptability of attentional-control training in survivors of pediatric cancer, currently…
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FDA approval · 2025-01-08FDA Approved: IMATINIB MESYLATE — Supplemental Application (Chartwell RX, LLC)
FDA approved a supplemental ANDA for Imatinib Mesylate (Chartwell RX, LLC), enabling marketing of a generic version of the cancer drug.
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic Leukemia
A clinical trial update on cancer care delivery for adolescent and young adult patients with acute lymphoblastic leukemia has completed. The…
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FDA label_change · 2025-01-03FDA Approved: DOXORUBICIN HYDROCHLORIDE — Supplemental Application (Zydus Lifesciences Limited)
FDA approved a supplemental application for doxorubicin hydrochloride from Zydus Lifesciences Limited, updating the labeling for the product…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Efficacy of Aleo Vera Use in Prevention and Treatment of Chemotherapy-Induced Oral Mucositis in a Group of Egyptian Children with Acute Leukemia [NA]
Completed clinical trial evaluating the efficacy of aloe vera for prevention and treatment of chemotherapy-induced oral mucositis in childre…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant with Dilanubicel for HIV-positive hematologic cancers; the study was terminated and results w…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Dolasetron for the Prevention of CINV in Children With Acute Lymphoblastic Leukemia
A clinical trial evaluating dolasetron to prevent chemotherapy-induced nausea and vomiting in children with acute lymphoblastic leukemia is …
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis [Phase 2, Phase 3]
A multi-agent trial in pediatric and young adult patients explores preventing graft-versus-host disease after transplantation using post-tra…
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: CD19/CD22 CAR-T Cell Therapy in MRD-Positive B-lineage Acute Lymphoblastic Leukemia in Children. [Phase 1]
This clinical trial update describes a Phase 1 study of a CD19/CD22 CAR-T cell therapy for MRD-positive B-lineage acute lymphoblastic leukem…
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FDA approval · 2024-12-26FDA Approved: CYCLOPHOSPHAMIDE — Original Application (Slate Run Pharmaceuticals, LLC)
FDA approves Slate Run Pharmaceuticals' original application for CYCLOPHOSPHAMIDE FOR INJECTION, expanding the market for a generic cyclopho…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Role of Cbc Indices in Acute Lymphoblastic Leukemia Patients [NA]
A clinical trial update from Sohag University describes a planned study on CBC indices in patients with acute lymphoblastic leukemia, curren…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors [Phase 1, Phase 2]
Clinical trial evaluating idasanutlin in combination with chemotherapy or venetoclax in pediatric and young adult relapsed/refractory acute …
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FDA approval · 2024-12-19FDA Approved: CYCLOPHOSPHAMIDE — Original Application (BluePoint Laboratories)
FDA approved BluePoint Laboratories' original ANDA for cyclophosphamide, establishing a generic version of the chemotherapy agent.
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Imaging of Chemotherapy-induced Morphological and Functional Lung Changes in Childhood ALL and HD [NA]
A pediatric clinical trial update examining imaging of chemotherapy-induced lung changes in childhood acute lymphoblastic leukemia and Hodgk…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Animal Assisted Interactions With Animal Robot in the Intensive Care Unit (ICU) [NA]
A completed clinical trial evaluating animal-assisted interactions using an animal robot in the ICU; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Prehospital Provider Training With Augmented Reality (AR) [NA]
A clinical trial evaluating prehospital provider training with augmented reality has completed. The provided snippet does not include effica…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia [Phase 1]
Phase 1 trial of fludarabine, cytarabine, and pegcrisantaspase for relapsed or refractory leukemias was terminated; the update notes the stu…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALL [Phase 2, Phase 3]
A phase 2/phase 3 trial evaluated clofarabine or high-dose cytarabine in combination with pegaspargase for children with acute lymphoblastic…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: T-cell Receptor α/β Depleted Donor Lymphocyte Infusion [Phase 1]
Phase 1 trial of T-cell receptor α/β-depleted donor lymphocyte infusion was terminated; results have been posted.
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: CD19-directed CAR-T Cell Therapy for R/R Acute Leukemia and Lymphoma [Phase 1, Phase 2]
Ongoing Phase 1/2 clinical trial from the University of Sao Paulo evaluating a CD19-directed CAR-T cell therapy for relapsed/refractory acut…
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FDA approval · 2024-12-09FDA Approved: IMATINIB MESYLATE — Supplemental Application (Mylan Pharmaceuticals Inc.)
The FDA approved a supplemental application for imatinib mesylate from Mylan Pharmaceuticals, effectively authorizing a supplemental approva…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Virtual Reality During Lumbar Punctures in Acute Lymphoblastic Leukemia [NA]
This clinical trial update describes a study examining virtual reality to alleviate pain during lumbar punctures in pediatric patients with …
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Psychiatric Problems in Children With Acute Lymphoblastic Leukemia and Their Caregivers
An update on a clinical trial studying psychiatric problems in children with acute lymphoblastic leukemia and their caregivers; the study is…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Administration of Donor MultiTAA-Specific T Cells for ALL [Phase 1]
This update reports the completion of a Phase 1 study evaluating donor multi-TAA-specific T cells for acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: An Extension Study to Evaluate the Safety and Efficacy of an Anti-CD19 CAR-T Product in Patients with B-cell Lymphoproliferative Disorders
An extension study to evaluate the safety and efficacy of an anti-CD19 CAR-T product in patients with B-cell lymphoproliferative disorders, …