Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 1]
Phase 1 study update for Orca-T in recipients undergoing allogeneic transplantation for hematologic malignancies; the trial is currently act…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Collecting and Storing Tissue From Young Patients With Cancer
A completed clinical trial update from the Children’s Oncology Group describing the collection and storage of tissue from pediatric cancer p…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Umbilical Vessel Catheterization Under ECG Monitoring and Guidance [NA]
An update on a clinical trial evaluating umbilical vessel catheterization under ECG monitoring in pediatric patients with acute lymphoblasti…
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Flumatinib Versus Imatinib Combined With Chemotherapy for de Novo Ph+ ALL [Phase 4]
Phase 4 clinical trial comparing flumatinib versus imatinib in combination with chemotherapy for newly diagnosed Philadelphia chromosome-pos…
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FDA approval · 2025-04-29FDA Approved: BLINCYTO — Supplemental Application (Amgen, Inc)
The FDA approved a supplemental application for BLINCYTO (blinatumomab) from Amgen, Inc., updating labeling and/or expanding the approved in…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Biomarkers in Patients With Anemia-Induced Thrombocytopenic Bleeding [NA]
This clinical trial update notes ongoing recruitment for a study examining biomarkers in patients with anemia-induced thrombocytopenic bleed…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Obinutuzumab Versus Rituximab for Acute Lymphoblastic Leukemia/PALG ALL7 "OVERALL" [Phase 2]
This is an ongoing Phase 2 clinical trial comparing obinutuzumab with rituximab in CD20-positive acute lymphoblastic leukemia, currently rec…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation [Phase 2]
Phase 2 trial evaluating tocilizumab to prevent graft-versus-host disease after cord blood transplantation has been completed.
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia [Phase 2]
This entry describes a Phase 2 clinical trial evaluating matched unrelated donor versus haploidentical donor approaches for allogeneic stem …
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Dutch Registry of Pediatric Cardiac Arrest
The document notes that the Dutch Registry of Pediatric Cardiac Arrest is currently recruiting for its registry, with conditions including c…
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FDA approval · 2025-04-22FDA Approved: DASATINIB — Original Application (Aurobindo Pharma Limited)
FDA approved the original ANDA for dasatinib from Aurobindo Pharma Limited (generic dasatinib).
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Inclusion Appeal Videos and Intent to Register for Pediatric Clinical Trials [NA]
This update reports on recruitment-focused efforts for pediatric acute lymphoblastic leukemia trials, including inclusion appeal videos and …
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial [Phase 2]
Phase 2 trial evaluating fecal microbiota transplantation before allogeneic stem cell transplant; recruitment is ongoing across multiple hem…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) [Phase 1]
Phase 1 clinical trial assessing a preventive therapy to reduce graft-versus-host disease in participants with hematologic malignancies unde…
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FDA approval · 2025-04-14FDA Approved: IMATINIB MESYLATE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' imatinib mesylate as an original (ANDA) generic product.
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: A Study to Evaluate the Long-term Safety of Patients With Advanced Lymphoid Leukemia Who Have Been Previously Administered With UCART19 [Phase 1]
A Phase 1 long-term safety study of UCART19 in patients with advanced lymphoid leukemia is ongoing (status: ACTIVE_NOT_RECRUITING).
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Breath Analysis for the Detection of Invasive Fungal Infections
This clinical trial update describes a breath analysis approach being studied to detect invasive fungal infections in patients with leukemia…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Hepatoprotective Measures for Children at High Risk of NAFLD [Phase 4]
Phase 4 clinical trial update on hepatoprotective measures for children at high risk of nonalcoholic fatty liver disease, including those wh…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: "Triple Negative" Adult B-cell Acute Lymphoblastic Leukemia - TRINEG-ALL
A clinical trial update for TRINEG-ALL investigating triple-negative adult B-cell acute lymphoblastic leukemia is currently recruiting. Spon…
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CLINICAL_TRIALS other · 2025-04-09Clinical Trial Update: Hepatoprotective for Children and Adolescent With Acute Lymphoblastic Leukemia [Phase 4]
Phase 4 clinical trial is recruiting a hepatoprotective therapy for children and adolescents with acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
This clinical trial update describes current ventilation strategies used in children undergoing general anesthesia, with recruitment ongoing…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation [Phase 1]
Phase 1 study evaluating itacitinib for prophylaxis of graft-versus-host disease and cytokine release syndrome after T-cell replete haploide…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched Donors [Phase 2]
A Phase 2 trial evaluating α/β+-T lymphocyte-depleted donor grafts from HLA-mismatched donors in multiple hematologic malignancies was termi…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017 [Phase 3]
This document reports a Phase 3 clinical trial protocol for treating children and adolescents with acute lymphoblastic leukemia, currently i…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: The Study for CML Who Failed Prior TKIs or With T315I Mutation or Ph+ ALL Who Failed Prior TKIs or With T315I Mutation [Phase 2]
Phase 2 clinical trial update for patients with chronic myeloid leukemia or acute lymphoblastic leukemia who failed prior TKIs or have the T…