Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders [Phase 1]
Phase 1 study of Veliparib with Topotecan, with or without Carboplatin, in relapsed or refractory acute leukemias, high-risk myelodysplastic…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: CARPALL: Immunotherapy with CD19+CD22 CAR T-cells for CD19+ and CD22+ Acute Lymphoblastic Leukaemia [Phase 1]
Phase 1 clinical trial evaluating CD19+CD22 CAR T-cells (CARPALL) for CD19+/CD22+ acute lymphoblastic leukemia. It is currently recruiting a…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia
This clinical trial compares standard chemotherapy with or without nelarabine or rituximab in newly diagnosed acute lymphoblastic leukemia a…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: CD22-CAR T Cells in Children and Young Adults With B Cell Malignancies [Phase 1]
This is a Phase 1 clinical trial update on CD22-directed CAR T cells for children and young adults with B-cell malignancies, including B-cel…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Latin American Real-world Study in Acute Leukemia
Pfizer-sponsored Latin American real-world study in acute leukemia has completed with results publicly posted.
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Motion Capture as a Tool for the Assessment of Laparoscopic Performance [NA]
Clinical trial update noting completion of a study that uses motion capture to assess laparoscopic performance.
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: A Phase I Clinical Trial of RS001 in Patients with Relapsed/Refractory B-Cell Malignancies [Phase 1]
A Phase 1 clinical trial of RS001 in relapsed/refractory B-cell malignancies, including B-cell Non-Hodgkin's Lymphoma and Acute Lymphoblasti…
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FDA approval · 2025-03-20FDA Approved: IMATINIB MESYLATE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for imatinib mesylate (Teva) under an ANDA, authorizing continued regulatory approval for this gener…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Efficacy of Short-course Blinatumomab for MRD Erradication in B-ALL [Phase 2]
Phase 2 clinical trial evaluating short-course blinatumomab for eradication of measurable residual disease in B-cell acute lymphoblastic leu…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: The Physical and Mental Health of People With Type II Diabetes Mellitus. [NA]
A completed clinical trial investigating the physical and mental health of adults with Type 2 diabetes mellitus.
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia Patients [Phase 3]
A Phase 3 trial is evaluating post-transplant cyclophosphamide as GVHD prophylaxis versus standard of care in acute leukemia patients in rem…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Raman Spectroscopy Compared to Flow Cytometry
A clinical trial update describing a study that compares Raman spectroscopy to flow cytometry for evaluating Acute Lymphoblastic Leukemia. T…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool [NA]
Completed pediatric trial evaluating an mHealth tool to improve COVID-19 vaccine uptake; results were posted March 11, 2025.
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Safety and Preliminary Efficacy of Donor-derived Anti-leukemia Cytotoxic T Lymphocytes for the Prevention of Leukemia Relapse in Children Given Haploidentical Hematopoietic Stem Cell Transplantation [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor-derived anti-leukemia cytotoxic T lymphocytes for preventing relapse after haploidentical stem cel…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease [Phase 2]
Phase 2 trial evaluating an umbilical cord blood transplant regimen with cyclophosphamide, fludarabine, and total-body irradiation for hemat…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating reduced-intensity conditioning with fludarabine and melphalan plus total body irradiation for haploidentical stem c…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Myeloablative Hematopoietic Progenitor Cell Transplantation (HPCT) for Pediatric Malignancies
This completed clinical trial evaluated myeloablative hematopoietic progenitor cell transplantation in pediatric patients with chronic myelo…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Effectiveness and Safety of InO±DLI for Relapsed B-ALL/LBL After Allo-HSCT [Phase 2]
Phase 2 clinical trial evaluating inotuzumab ozogamicin with or without donor lymphocyte infusion for relapsed B-lymphoblastic leukemia or l…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: A Swiss Assessment of Hypothalamic-pituitary-adrenal Axis Suppression After Glucocorticoid Therapy for Leukemia and Lymphoblastic Lymphoma in Children
This ClinicalTrials.gov update describes a pediatric study at University Children's Hospital Basel evaluating how glucocorticoid therapy for…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Thiotepa, Cyclophosphamide, Clarithromycin and Cytarabine [Phase 1]
A Phase 1 clinical trial evaluating a thiotepa, cyclophosphamide, clarithromycin, and cytarabine combination in adults with Burkitt lymphoma…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Safely Delivered Targeted High-dose Irradiation Followed by Adoptive Immunotherapy with Regulatory and Conventional T Cells to Increase Potency of Hematopoietic Stem Cell Transplantation in High-risk Acute Leukemia [NA]
This clinical trial update describes testing a treatment strategy that uses targeted high-dose irradiation followed by adoptive immunotherap…
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FDA approval · 2025-03-03FDA Approved: DASATINIB — Original Application (Biocon Pharma Inc.)
FDA approves Biocon Pharma Inc.'s original application for dasatinib (generic) to treat certain leukemias, marking the availability of a gen…
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FDA approval · 2025-03-03FDA Approved: DASATINIB — Original Application (Dr.Reddys Laboratories Inc)
FDA approved the original application for dasatinib by Dr. Reddy's Laboratories Inc, providing a generic version of dasatinib for leukemias.…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Psychometric Properties of the Therapy-Related Symptom Checklist-Children
This clinical trial update evaluates the psychometric properties of the Therapy-Related Symptom Checklist-Children and its use in pediatric …
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: Obesity Prevention in Children and Young People Treated for Acute Lymphoblastic Leukaemia with ALLTogether [NA]
Clinical trial update on obesity prevention in children treated for acute lymphoblastic leukemia using the ALLTogether program; the study is…