Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation [Phase 2]
Phase 2 trial comparing three GVHD prophylaxis regimens in nonmyeloablative or reduced-intensity conditioning unrelated donor transplantatio…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Expanded Access to Ziftomenib
Kura Oncology announces expanded access to the investigational menin inhibitor ziftomenib for eligible patients with acute lymphoblastic leu…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: CD19 CAR T Cells in Patients With Resistant or Refractory CD19+ Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 study of CD19-directed CAR T cells in patients with resistant or refractory CD19-positive acute lymphoblastic leukemia has completed…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: A Triple-targeted Cell Preparation Targeting CD19/CD20/CD22 in Patients With Relapsed/Refractory B-cell Acute Lymphocytic Leukemia [Phase 1]
A Phase 1 trial of a triple-targeted CD19/CD20/CD22 CAR-T cell therapy for relapsed/refractory B-cell acute lymphoblastic leukemia has been …
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: European Prospective Investigation Into Childhood Cancer
The European Prospective Investigation Into Childhood Cancer trial is currently recruiting, studying acute lymphoblastic leukemia and brain …
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants [Phase 2]
Phase 2 clinical trial update describing the addition of itacitinib to cyclophosphamide and tacrolimus for preventing graft-versus-host dise…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Intravenous Autologous CD19 CAR-T Cells for R/ R MM, B-ALL, and B-Cell Lymphoma [NA]
A clinical trial is evaluating intravenous autologous CD19 CAR-T cells for relapsed or refractory lymphoblastic leukemia and relapsed/refrac…
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EMA approval · 2025-05-23New treatment for adults with acute lymphoblastic leukaemia
The EMA approved brexucabtagene autoleucel (Tecartus) for adults with acute lymphoblastic leukemia, marking the third CAR T-cell therapy app…
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: DS-1594b With or Without Azacitidine, Venetoclax, or Mini-HCVD for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
A phase 1/2 study of DS-1594b with or without azacitidine, venetoclax, or mini-HCVD in relapsed or refractory acute myeloid leukemia or acut…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Precursor B Cell Acute Lymphoblastic Leukemia (B-ALL) Treated With Autologous T Cells Genetically Targeted to the B Cell Specific Antigen CD19 [Phase 1]
Phase 1 study of autologous CD19-targeted CAR-T cells for precursor B-cell acute lymphoblastic leukemia. The trial status is active but not …
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: A Study of Blinatumomab in Patients With Pre B-cell ALL and B-cell NHL as Post-allo-HSCT Remission Maintenance [Phase 1, Phase 2]
A Phase 1/2 study of blinatumomab in patients with Pre-B cell acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma as remission main…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Supporting Parents to Choose Wisely [NA]
A completed University of Alberta clinical trial evaluated decision-support tools to help parents choose care for children with several comm…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Study of Anti-CD22 CAR-T Cells Treating Leukemia Children [Phase 2]
A Phase 2 clinical trial evaluating anti-CD22 CAR-T cells for pediatric acute lymphoblastic leukemia has completed, including relapsed and r…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Phase II Study of Anti-CD19 CAR-T Cells Treating Leukemia Children [Phase 2]
Phase II trial evaluating anti-CD19 CAR-T cell therapy for pediatric acute lymphoblastic leukemia, including relapsed and refractory cases; …
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Feasibility Study to Evaluate Outpatient Blinatumomab in Subjects With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (ALL) [Phase 4]
A Phase 4 feasibility trial evaluating outpatient administration of blinatumomab in patients with minimal residual disease in B-cell precurs…
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Study of huCART19 for Very High-Risk (VHR) Subsets of Pediatric B-ALL [Phase 2]
A Phase 2 study evaluating huCART19 for very high-risk pediatric B-cell acute lymphoblastic leukemia has completed and results have been pos…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Bortezomib-based Regimen for Refractory or Relapsed Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating a bortezomib-based regimen for refractory or relapsed acute lymphoblastic leukemia, currently recruiting.
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CLINICAL_TRIALS other · 2025-05-16Clinical Trial Update: Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies [Phase 1]
Phase 1 clinical trial evaluating Genetically Engineered Anti-CD19/CD20/CD22 CAR T-cells for relapsed or refractory lymphoid malignancies; c…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Palliative Care Oncology in Patients With Relapsed, Refractory, and High-Risk Leukemias or MDS [Phase 2]
This clinical trial update describes a Phase 2 study evaluating palliative care oncology in adults with relapsed, refractory, or high-risk a…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: HEalth Advocate for Liver Transplantation: Improving Transition of Care for Adolescent Liver Transplant Recipients [NA]
This clinical trial update indicates that UCSF is recruiting for a study titled Health Advocate for Liver Transplantation, aimed at improvin…
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Augmentation of the Graft vs. Leukemia Effect Via Checkpoint Blockade With Pembrolizumab [Phase 1]
Phase 1 study evaluating pembrolizumab to augment graft-versus-leukemia effect in patients with myelodysplastic syndromes and acute myeloid …
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Accuracy Performance Verification of the INVOS™ System in Pediatrics
A completed clinical trial evaluating the accuracy of the INVOS System for measuring cerebral oxygenation in pediatric patients, including t…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia [Phase 1, Phase 2]
A Phase 1/2 study evaluating venetoclax, ponatinib, and dexamethasone in patients with BCR-ABL1 positive Philadelphia chromosome positive re…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil
Clinical trial in Brazil is evaluating whether a pediatric regimen can be used to treat adults with acute lymphoblastic leukemia; the study …
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children [Phase 2]
This clinical trial update describes a Phase 2 study evaluating KIR-favorable mismatched haploidentical transplantation and KIR polymorphism…