Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: VR-PAT During Home Burn Dressings - Multisite [NA]
A multisite clinical trial evaluating VR-PAT for pain management during home burn dressings is currently enrolling by invitation.
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma [Phase 1, Phase 2]
This clinical trial update summarizes the Phase 1/2 results of oral ixazomib in combination with chemotherapy for pediatric patients with re…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Pilot Study of T-APCs Following CAR T Cell Immunotherapy for CD19+ Leukemia [Phase 1]
Phase 1 pilot study evaluating T-APCs after CAR T cell immunotherapy for CD19-positive acute leukemia is active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: A Pediatric Trial of Genetically Modified Autologous T Cells Directed Against CD19 for Relapsed CD19+ Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 pediatric trial evaluating autologous CD19-directed CAR-T cells for relapsed CD19-positive acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: A Study of Venetoclax in Combination With Chemotherapy to Treat Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) [EARLY_Phase 1]
An update on a phase 1 study of venetoclax with chemotherapy for newly diagnosed Acute Lymphoblastic Leukemia, currently not recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases [Phase 2]
A Phase 2 clinical trial is testing alpha/beta T cell and CD19+ B cell depletion in allogeneic stem cell transplantation for malignant disea…
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CLINICAL_TRIALS other · 2025-06-15Clinical Trial Update: The EPigenetic Consequences in Children of Intravenous vs Volatile Anaesthesia for Surgery (EPIVA) [NA]
This update reports on the EPIVA clinical trial comparing intravenous versus volatile anesthesia in children and its potential epigenetic im…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: ALL Adult Consortium Trial: Adult ALL Trial [Phase 2]
A Phase 2 trial in adults with acute lymphoblastic leukemia (ALL) completed for the ALL Adult Consortium; results have been posted.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Feasibility of a Life Coping Program: A Study Protocol [NA]
Completed study protocol reporting the feasibility of a life coping program to improve health-related quality of life and health literacy, w…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell Malignancies [Phase 1]
Phase 1 trial update describing the use of allogeneic Epstein-Barr virus-specific cytotoxic T-lymphocytes targeted to CD19 for B-cell malign…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Treatment of Newly Diagnosed High Risk Pediatric Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating treatment for newly diagnosed high-risk pediatric acute lymphoblastic leukemia; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in Children [Phase 2]
This entry describes a Phase 2 clinical trial evaluating treatment for newly diagnosed standard-risk acute lymphoblastic leukemia in childre…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Treatment of Pediatric Very High-risk Acute Lymphoblastic Leukemia in Korea [Phase 2]
A Phase 2 clinical trial in Korea evaluating treatment for pediatric patients with very high-risk acute lymphoblastic leukemia is currently …
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Insomnia Prevention in Children With Acute Lymphoblastic Leukemia [NA]
Completed clinical trial investigating insomnia prevention in children with acute lymphoblastic leukemia; results have been posted on 2025-0…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Evaluation of Treatment Efficacy According to Risk Group in Relapsed Childhood Acute Lymphoblastic Leukemia [Phase 2]
Ongoing Phase 2 clinical trial evaluating treatment efficacy by risk group in relapsed childhood acute lymphoblastic leukemia, currently rec…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Effectiveness and Safety of Tisagenlecleucel Therapy in Brazilian Patients With B-lymphocyte Malignancies
A clinical trial is investigating the effectiveness and safety of the CAR-T therapy tisagenlecleucel in Brazilian patients with B-lymphocyte…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: CD7 CAR-T Cell Therapy Targeting CD7-positive Relapsed/Refractory T Cell Lymphoma/Acute Leukemia [NA]
A clinical trial evaluating a CD7-targeted CAR-T cell therapy for relapsed/refractory CD7-positive T-cell lymphoma and CD7-positive acute ly…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating post-transplant use of inotuzumab ozogamicin for acute lymphoblastic leukemia; the study is currently recru…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: CD19 CAR-T Consolidation Therapy for Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating CD19 CAR-T consolidation therapy for adult B-cell acute lymphoblastic leukemia, and the study…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Pediatric Vaccinations
This entry notes an ongoing clinical trial sponsored by NYU Langone Health exploring pediatric vaccination approaches, including considerati…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL [Phase 1, Phase 2]
A Phase 1/Phase 2 trial at Dana-Farber Cancer Institute is evaluating Venetoclax plus chemotherapy as frontline therapy for older patients a…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 trial results update for carfilzomib in combination with induction chemotherapy in children with relapsed or refractory acute lympho…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies [Phase 1]
Phase 1 study evaluating CD19/CD22 CAR T cells in children and young adults with recurrent or refractory CD19/CD22-expressing B cell maligna…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD [Phase 2]
Phase 2 clinical trial assessing selective depletion of CD45RA+ T cells from allogeneic stem cell grafts to prevent graft-versus-host diseas…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis [Phase 2]
A Phase 2 trial (ABBA CORD) evaluating donor-derived cord blood T cells with abatacept for prophylaxis of acute graft-versus-host disease in…