Acute Lymphoblastic Leukemia
📧 Sign up to get email alerts when something new happens for Acute Lymphoblastic Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS other · 2025-07-10Clinical Trial Update: Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies
Administrative update on a trial collecting biological samples from patients treated with CAR-T cells for lymphoma and acute lymphoblastic l…
-
CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT [Phase 1]
Phase 1 trial evaluating multi-virus cytotoxic T lymphocytes engineered with CD19 chimeric receptors for CD19-positive malignancies after st…
-
CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: 90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial of a radiolabeled anti-CD25 antibody with fludarabine, melphalan, and total marrow and lymphoid irradiation for high-…
-
CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT [Phase 2]
This Phase 2 trial comparing post-transplant cyclophosphamide (PTCy) plus ruxolitinib versus PTCy with tacrolimus and MMF in matched related…
-
CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep [Phase 2]
Phase 2 clinical trial evaluating non-myeloablative preparative regimens followed by umbilical cord blood transplantation for various hemato…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS withdrawal · 2025-07-04Clinical Trial Update: Difficult PIV Placement in the Pediatric ED [NA]
The clinical trial NCT06013904 evaluating difficult peripheral IV placement in pediatric ALL patients has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2025-07-03Clinical Trial Update: Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL [Phase 1]
The Phase 1 study of BMF-219, Biomea Fusion's covalent menin inhibitor, in adults with AML, ALL, DLBCL, multiple myeloma, and CLL/SLL has be…
-
CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Human AntiCD19 Chimeric Antigen Receptor T Cells for Relapsed or Refractory Lymphoid Malignancies [Phase 1]
Phase 1 clinical trial evaluating human anti-CD19 CAR-T cells for relapsed or refractory lymphoid malignancies is currently active but not r…
-
CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Adding Ruxolitinib to a Combination of Dasatinib Plus Dexamethasone in Remission Induction Therapy in Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Patients Aged 40 Years or Older [Phase 1]
This clinical trial update describes adding ruxolitinib to a dasatinib plus dexamethasone induction regimen for newly diagnosed Philadelphia…
-
CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR) [Phase 1]
Phase 1 study update for CD19 CAR-allogeneic NKT therapy (ANCHOR) in relapsed or refractory B-cell malignancies; the trial is currently acti…
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Allo HSCT Using RIC and PTCy for Hematological Diseases [Phase 2]
Phase 2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation using reduced-intensity conditioning and post-transplan…
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Investigation of Remimazolam in Children Undergoing Sedation for Medical Procedures [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial update assessing remimazolam for sedation in children undergoing medical procedures, sponsored by Acacia Ph…
-
CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Online Physical Activity and Health Counseling for Survivors of Childhood Acute Lymphoblastic Leukemia [NA]
A clinical trial update describes an online physical activity program and health counseling for survivors of childhood acute lymphoblastic l…
-
CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning [Phase 2]
Phase 2 trial evaluating vedolizumab with post-transplant cyclophosphamide and tacrolimus to prevent graft-versus-host disease in patients u…
-
FDA approval · 2025-06-26FDA Approved: MERCAPTOPURINE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved Hikma Pharmaceuticals USA Inc.'s supplemental application for mercaptopurine, enabling continued marketing of the generic p…
-
CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: A Real-world Study of the Effectiveness of Tisagenlecleucel in Acute Lymphoblastic Leukemia Patients
This clinical trial update summarizes real-world effectiveness data for tisagenlecleucel in patients with acute lymphoblastic leukemia.
-
CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: CAR-Multicenter Analysis (CAR-MA): Retrospective Study to Characterize CAR T-cell Outcomes and Related Toxicities in Children and Young Adults With B-ALL
Multicenter retrospective analysis assessing CAR T-cell therapy outcomes and related toxicities in children and young adults with B-cell acu…
-
CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Biology and Benefits of Music Play and Stories for Kids/Parents During ALL Treatment [NA]
A completed clinical trial evaluating the biology and benefits of music play and storytelling for children undergoing treatment for acute ly…
-
CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: BCOR and ZC3H12 Genes Knock-out CD19-targeting CAR-T Cell Therapy in r/r B-ALL [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a CD19-targeting CAR-T cell therapy with BCOR and ZC3H12 gene knock-out for relapsed/refractory B-c…
-
CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders [Phase 2]
Phase 2 clinical trial evaluating myeloablative allogeneic hematopoietic stem cell transplantation from related or unrelated donors for a br…
-
CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: The Safety and Efficay Investigation of CAR-T Cell Therapy for Patients With Hematological Malignancies [NA]
A clinical trial is recruiting to evaluate an investigational CAR-T cell therapy for hematologic malignancies, including acute lymphoblastic…
-
CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia [Phase 1]
A Phase 1 clinical trial evaluating total marrow and lymphoid irradiation with chemotherapy before donor transplantation in patients with my…
-
CLINICAL_TRIALS withdrawal · 2025-06-22Clinical Trial Update: A Study of JNJ-75276617 in Combination With Conventional Chemotherapy for Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias [Phase 1]
A Phase 1 trial of JNJ-75276617 in combination with conventional chemotherapy for pediatric and young adult patients with relapsed/refractor…
-
CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: The Effect of Non-pharmacological Methods on Pain, Fear [NA]
A clinical trial update describing a study of non-pharmacological methods to reduce pain and fear in children, including those with pediatri…
-
CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL) [NA]
Clinical trial update for a nutrition and exercise program in adults undergoing treatment for acute lymphoblastic leukemia (ALL); the study …