Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors [Phase 1]
Phase 1 pediatric trial evaluating alpha/beta CD19+ depleted haploidentical transplantation in combination with Zoledronic acid (Zometa) for…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: 211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
This trial evaluates a targeted radiopharmaceutical (211At-BC8-B10) followed by an allogeneic donor stem cell transplant for relapsed or ref…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating naive T cell depletion to prevent chronic graft-versus-host disease in children and young adults receiving…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: CART22 Alone or in Combination With huCART19 for ALL [Phase 1]
A Phase 1 study at University of Pennsylvania evaluating CART22 alone or in combination with huCART19 for chemotherapy-resistant or refracto…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: A Bilingual Virtually-based Intervention (PEDALL) for the Prevention of Weight Gain in Childhood ALL Patients Considering Key Genetic and Sociodemographic Risk Factors [NA]
A clinical trial update for PEDALL, a bilingual virtual intervention to prevent weight gain in children with acute lymphoblastic leukemia, c…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Treatment of Older Patients With B-precursor ALL With Sequential Dose Reduced Chemotherapy and Blinatumomab [Phase 2]
Phase 2 trial in older patients with B-cell precursor acute lymphoblastic leukemia evaluating sequential dose-reduced chemotherapy followed …
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Bio-CAR-T BS Study
A clinical trial update indicates the Bio-CAR-T BS study is currently recruiting for diffuse large B-cell lymphoma, primary mediastinal B-ce…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Efficacy of Low-dose Venetoclax With Itraconazole + TACL for R/R ALL Patients [Phase 2]
Phase 2 clinical trial update evaluating low-dose venetoclax with itraconazole and TACL for relapsed/refractory acute lymphoblastic leukemia…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Efficacy of Targeted Drugs Combined With Chemotherapy in the Treatment of T-ALL [Phase 3]
A Phase 3 clinical trial evaluating targeted drugs combined with chemotherapy for T-cell acute lymphoblastic leukemia is currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: An Endotracheal Tube Inserted to the Level of the Hypopharynx
A completed clinical trial from American University of Beirut Medical Center studied endotracheal tube placement up to the hypopharynx, incl…
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FDA approval · 2025-09-30FDA Approved: DASATINIB — Supplemental Application (Dr.Reddys Laboratories Inc)
The FDA has approved a supplemental application for dasatinib from Dr. Reddy's Laboratories Inc, authorizing an update to the approval of th…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: BAFFR CAR-T Treatment for Relapsed/Refractory B-cell Tumors [EARLY_Phase 1]
A phase 1 clinical trial of BAFFR CAR-T therapy for relapsed/refractory B-cell tumors is not yet recruiting, sponsored by Guangzhou Bio-gene…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Retun-to-school Adaptation Program for Children With Cancer [NA]
Clinical trial update indicating the completion of a return-to-school adaptation program study for children with cancer, sponsored by Gazi U…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 3]
A Phase 3 randomized trial evaluating Orca-T in allogeneic stem cell transplantation for hematologic malignancies; results have been posted.
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies [EARLY_Phase 1]
An early-phase trial evaluating Darzalex Faspro (daratumumab and hyaluronidase-fihj) given before desensitization and allogeneic stem cell t…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Phase I Clinical Study of GNC-038 in Patients With Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia [Phase 1]
Phase I clinical trial update for GNC-038 in non-Hodgkin lymphoma and acute lymphoblastic leukemia; the study is currently not recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Improving Nighttime Access to Care and Treatment; Part 2- Ghana [NA]
This update reports completion of a clinical trial aiming to improve nighttime access to care and treatment for pediatric acute lymphoblasti…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies [Phase 1]
A Phase 1 clinical trial update for CD19-directed CAR-T cell therapy in patients with refractory or relapsed B lymphoid malignancies is curr…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study
The CREST study update shows the cardiovascular reserve evaluation trial in transplant survivors is currently active but not recruiting, spo…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: Blinatumomab in Treating Patients With B-cell Acute Lymphoblastic Leukemia With Minimal Residual Disease [Phase 2]
Phase 2 trial assessing blinatumomab in adults with B-cell acute lymphoblastic leukemia in complete remission who have minimal residual dise…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability
The PANDA Gym study is an ongoing clinical trial that uses automated assessment of neurodevelopment in infants at risk for motor disability …
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Study of Brexucabtagene Autoleucel Plus Dasatinib in Adults With Acute Lymphoblastic Leukemia [Phase 1]
A Phase 1 clinical trial evaluating the combination of brexucabtagene autoleucel (Tecartus) with dasatinib in adults with acute lymphoblasti…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19 [Phase 1]
A Phase 1 clinical trial update describing CD19-targeted CAR T-cell immunotherapy for high-risk or relapsed CD19+ acute lymphoblastic leukem…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax [Phase 1, Phase 2]
A Phase 1/2 trial at St. Jude evaluating the combination of venetoclax and navitoclax for relapsed or refractory acute lymphoblastic leukemi…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Phase I Clinical Trial of CART Cell Therapy for Refractory/Relapsed Acute Lymphoblastic Leukemia in Children, Adolescents and Young Adults [Phase 1]
A Phase I clinical trial update describing CART cell therapy for refractory/relapsed acute lymphoblastic leukemia in children, adolescents, …