Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: A Multi-center Retrospective Study of INO Treating B-ALL
A multi-center retrospective study evaluating Inotuzumab Ozogamicin for B-cell acute lymphoblastic leukemia, with Venetoclax as part of the …
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Study of the Medullary Microenvironment in Acute Childhood Leukemia [NA]
A pediatric clinical trial is investigating the medullary microenvironment in acute lymphoblastic leukemia and acute myeloid leukemia; the s…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
A clinical trial update describing a study to assess how exercise affects fitness and lung function in survivors of heart transplant, acute …
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: To Evaluate the Safety, Tolerability, and Preliminary Antitumor Activity of STR-P004 [NA]
A clinical trial update outlines evaluating STR-P004 for safety, tolerability, and preliminary antitumor activity in acute lymphoblastic leu…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: VR-PAT and fNIRS to Identify CNS Biomarkers of Pain [NA]
This clinical trial update describes using VR-PAT and fNIRS to identify CNS biomarkers of pain in pediatric patients, with conditions includ…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Inotuzumab Ozogamicin in the Treatment of MRD+ After HSCT of ALL [Phase 2]
Phase 2 clinical trial investigating inotuzumab ozogamicin for patients with acute lymphoblastic leukemia who remain MRD-positive after hema…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL [Phase 1]
A Phase 1 clinical trial update evaluating the combination of ribociclib, everolimus, and dexamethasone for relapsed acute lymphoblastic leu…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Veliparib and Temozolomide in Treating Patients With Acute Leukemia [Phase 1]
Phase 1 study of veliparib plus temozolomide in adults with acute lymphoblastic leukemia or acute myeloid leukemia has completed enrollment,…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant [Phase 1]
This clinical trial update describes a Phase 1 study evaluating HA-1 TCR T-cell immunotherapy for relapsed or refractory acute leukemia afte…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL) [Phase 1]
A Phase 1 trial evaluating a trivalent CAR-T cell therapy for acute B-lineage leukemia is currently recruiting (TRICAR-ALL).
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer [Phase 1]
A Phase 1 trial evaluating natural killer cell therapy in combination with Interleukin-2 and the TGF-beta receptor I inhibitor vactosertib f…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: ALL Backbone in AYAs [Phase 2]
Phase 2 clinical trial evaluating the ALL Backbone regimen in adolescents and young adults with acute lymphoblastic leukemia; the study is c…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia [EARLY_Phase 1]
This early-phase clinical trial evaluates the safety and feasibility of combining allogeneic CMV-specific CD19-CAR T cells with the CMV-MVA …
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Haploidentical BMT With Post-Transplant Cyclophosphamide and Bendamustine [Phase 1]
A Phase 1 clinical trial evaluating a haploidentical bone marrow transplant using post-transplant cyclophosphamide and bendamustine has comp…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial update on Orca-T after chemotherapy and total marrow and lymphoid irradiation for acute myeloid leukemia, acute lymph…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: huCART19-IL18 in CD19+ Cancers [Phase 1]
Phase 1 clinical trial of huCART19-IL18 for CD19+ cancers is currently ACTIVE_NOT_RECRUITING, sponsored by the University of Pennsylvania, i…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Personalized NK Cell Therapy in CBT [Phase 2]
A Phase 2 trial from MD Anderson is evaluating personalized NK cell therapy across several hematologic cancers. The study is currently recru…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid Malignancies [Phase 1, Phase 2]
Phase 1/2 trial evaluating rapamycin added to high-dose etoposide and cytarabine in relapsed/refractory aggressive lymphoid malignancies; th…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial evaluating ruxolitinib with tacrolimus and methotrexate to prevent graft-versus-host disease in pediatric and young adult pa…
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Two Step Haplo With Radiation Conditioning [Phase 2]
Phase 2 clinical trial update describing two-step haploidentical transplantation with radiation conditioning for hematologic diseases, curre…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL [Phase 1, Phase 2]
This clinical trial update concerns autologous CD19 CAR-T cell therapy with an inducible safety switch for relapsed/refractory acute lymphob…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Healthy Weight Intervention Families During ALL Treatment: NOURISH-ALL
NOURISH-ALL is a pediatric clinical trial examining a healthy weight intervention for families during treatment of childhood acute lymphobla…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy [Phase 1]
Phase 1 trial evaluating Vincristine sulfate liposome injection with UK ALL R3 induction chemotherapy for pediatric acute lymphoblastic leuk…
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FDA label_change · 2025-10-21FDA Approved: BLINCYTO — Supplemental Application (Amgen, Inc)
FDA approved a supplemental application for BLINCYTO (blinatumomab) submitted by Amgen to update the labeling. The change reflects an expand…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: A Study in Adults With Untreated Acute Lymphoblastic Leukemia [Phase 2]
This is a Phase 2 trial update in adults with untreated acute lymphoblastic leukemia. Results for the study have been posted.