Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy [Phase 2]
A Phase 2 clinical trial update notes evaluation of siltuximab for treating cytokine release syndrome (CRS) and ICANS related to CAR-T cell …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Safety Study of CC312 in Adult Patients With Relapsed/Refractory CD19 Positive B-cell Hematologic Malignancies [Phase 1]
This clinical trial update describes a Phase 1 safety study of CC312 in adults with relapsed/refractory CD19-positive B-cell hematologic mal…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS [Phase 1, Phase 2]
Update on a Phase 1/2 trial of BSB-1001 in patients undergoing HLA-matched allogeneic hematopoietic stem cell transplantation for acute myel…
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EMA approval · 2025-09-17EMA Authorised: Besponsa (Inotuzumab ozogamicin) — Pfizer Europe MA EEIG
The European Medicines Agency authorised Besponsa (inotuzumab ozogamicin) for precursor cell lymphoblastic leukemia-lymphoma under Pfizer Eu…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Multicenter Study on Rehabilitation Medical Data for Pediatric Big Brain Development
A multicenter clinical trial collecting rehabilitation data to study pediatric brain development and is currently recruiting, enrolling part…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial is evaluating a pediatric-inspired regimen with reduced myelosuppressive drugs for adults age 18-60 with newly diag…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies [Phase 1, Phase 2]
This clinical trial registration outlines a Phase 1/2 pediatric study of a multi-drug regimen (dasatinib, venetoclax, dexamethasone, cycloph…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies [Phase 1, Phase 2]
Ongoing Phase 1/Phase 2 clinical trial evaluating trametinib with dexamethasone and chemotherapy in children with relapsed or refractory acu…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: GT719 Injection for the Treatment of Recurrent/Refractory CD19 Positive Adult B-cell Malignancies [Phase 1, Phase 2]
GT719 Injection is being studied in a Phase 1/2 trial for recurrent or refractory CD19-positive adult B-cell malignancies, with recruitment …
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: A French Protocol for the Treatment of Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents [Phase 3]
Phase 3 French protocol for treating acute lymphoblastic leukemia in children and adolescents. The trial is currently active but not recruit…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies [Phase 1, Phase 2]
Clinical trial update for HEM-iSMART-C evaluating ruxolitinib, venetoclax, dexamethasone, cyclophosphamide, and cytarabine in pediatric pati…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Feasibility Neurocognitive Outcome After Transplant [NA]
This is an update on a pediatric stem cell transplant trial assessing feasibility of neurocognitive outcomes in children with acute lymphobl…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies [Phase 1, Phase 2]
This pediatric Phase 1/2 clinical trial evaluates capivasertib plus venetoclax and dexamethasone for relapsed or refractory hematologic mali…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children
A pediatric clinical trial is studying whether skin color affects the accuracy of pulse oximetry in children, with recruitment ongoing and i…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Long Term Follow-up Study of TScan TCR-T Products
This clinical trial update describes a long-term follow-up study of TScan Therapeutics' TCR-T cell therapies for acute myeloid leukemia, acu…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: The Effect of Child-centered Empowerment on Lifestyle of Leukemia Patients [NA]
A completed clinical trial from Near East University evaluated whether a child-centered empowerment program can improve lifestyle among pati…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: This is a Phase I/II Interventional, Open-label Treatment Study Designed to Evaluate the Safety and Efficacy of Anti CD 19/22 CAR- T Cells Immunotherapy for Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia/Lymphoma. [Phase 1, Phase 2]
This Phase I/II open-label trial evaluates an anti-CD19/CD22 CAR-T cell therapy in adults with relapsed or refractory acute lymphoblastic le…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Evaluating the Effectiveness of Respiratory Muscle Training in Pediatric Kidney Transplant Patient [NA]
A completed clinical trial evaluating the effectiveness of respiratory muscle training in pediatric patients with chronic kidney disease, in…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Cord Blood Transplant in Adults With Blood Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant in adults with blood cancers is currently recruiting. Conditions include acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Levocarnitine and Vitamin B Complex in Treating PEG-Asparaginase or Inotuzumab Ozogamicin-Induced Hyperbilirubinemia in Patients With Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 study evaluating levocarnitine with vitamin B complex to treat hyperbilirubinemia caused by PEG-asparaginase or inotuzumab ozogamici…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant [Phase 2]
The update describes a Phase 2 study of a modified dose of rabbit anti-thymocyte globulin (rATG) used to condition patients (children and ad…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Newly-diagnosed Pediatric Ph-positive B-ALL Protocol [Phase 3]
Phase 3 clinical trial protocol for newly diagnosed Philadelphia chromosome-positive pediatric acute lymphoblastic leukemia, currently recru…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Early Assessment of Cardiac Function After Treatment With CAR-T Cells
A clinical trial update reporting early cardiac function assessment in patients treated with CAR-T cell therapy for hematologic malignancies…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: A Treatment Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
A trial protocol for participants aged 0-45 with acute lymphoblastic leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: A Study of Different Programs to Help ALL Patients With Taking Maintenance Medicine at Home [NA]
A clinical trial evaluating programs to help children with acute lymphoblastic leukemia maintain home-based maintenance medication has been …