Uveal Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2018-06-26Clinical Trial Update: Validation of a Molecular Prognostic Test for Eye Melanoma
A clinical trial validating a molecular prognostic test for eye melanoma has been withdrawn. The sponsor is Washington University School of …
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CLINICAL_TRIALS trial_result · 2018-04-24Clinical Trial Update: Pembrolizumab in Treating Patients With Advanced Uveal Melanoma [Phase 2]
Phase 2 trial of pembrolizumab in advanced uveal melanoma was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Epacadostat and Vaccine Therapy in Treating Patients With Stage III-IV Melanoma [Phase 2]
Phase 2 study evaluating epacadostat with a vaccine therapy in patients with stage III-IV melanoma has completed and posted results.
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CLINICAL_TRIALS withdrawal · 2017-12-12Clinical Trial Update: Efficacy and Safety Study of GSK1120212, a MEK Inhibitor, in Subjects With Uveal Melanoma [Phase 2]
A Phase 2 clinical trial evaluating the MEK inhibitor GSK1120212 in patients with uveal melanoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Study of AntiCTLA4 in Patients With Unresectable or Metastatic Uveal Melanoma [Phase 2]
Phase 2 clinical trial evaluating an anti-CTLA-4 antibody in patients with unresectable or metastatic uveal melanoma has completed.
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CLINICAL_TRIALS trial_result · 2017-10-23Clinical Trial Update: Liver Transplantation and Uveal Malignant Melanoma [NA]
The ClinicalTrials.gov entry indicates that a study evaluating liver transplantation in patients with uveal melanoma has completed.
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: RAD001 (Everolimus) and Pasireotide (SOM230) LAR in Patients With Advanced Uveal Melanoma [Phase 2]
Phase 2 trial evaluating the combination of everolimus (RAD001) and pasireotide long-acting release (SOM230 LAR) in patients with advanced u…
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Ocular Melanoma [Phase 2]
Phase 2 trial evaluating tumor-infiltrating lymphocytes (TIL) immunotherapy for metastatic ocular/uveal melanoma; study terminated with resu…
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CLINICAL_TRIALS trial_result · 2017-05-18Clinical Trial Update: Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the Eye [Phase 2]
A Phase 2 clinical trial evaluating temozolomide or selumetinib for metastatic melanoma of the eye (uveal/iris melanoma) has completed, with…
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: TTT Versus TTT and Triamcinolone to Decrease Exudation in Choroidal Melanoma After Proton Beam Therapy [Phase 4]
Phase 4 clinical trial comparing TTT alone versus TTT with Triamcinolone to decrease exudation in choroidal/uveal melanoma after proton beam…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Vaccine Therapy in Treating Patients With Advanced Melanoma [Phase 1]
Phase 1 clinical trial of a melanoma vaccine therapy has completed. The study evaluated safety in patients with advanced melanoma, including…
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CLINICAL_TRIALS trial_result · 2016-10-20Clinical Trial Update: A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma [Phase 1, Phase 2]
Phase Ib/II study of AEB071 (tavimel) and MEK162 in adult patients with metastatic uveal melanoma was terminated with results posted in 2016…
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: Selumetinib (AZD6244: ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT) [Phase 3]
Phase 3 SUMIT trial evaluating selumetinib (AZD6244) in metastatic uveal melanoma has completed, with results posted on 2016-09-28.
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CLINICAL_TRIALS trial_result · 2016-07-07Clinical Trial Update: Combined PET/CT Imaging for the Early Detection of Ocular Melanoma Metastasis Compared to CT Scanning Alone
A completed trial comparing combined PET/CT imaging to CT alone for early detection of ocular melanoma metastasis.
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Radiation Therapy in Preventing Liver Metastases in Patients With Uveal Melanoma Who HaveMonosomy 3 or DecisionDx Class 2 Disease and Are More Likely to Develop Liver Metastases [NA]
Clinical trial evaluating radiation therapy to prevent liver metastases in uveal melanoma patients with high risk features; study terminated…
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CLINICAL_TRIALS trial_result · 2016-03-10Clinical Trial Update: Radioembolization and Ipilimumab in Treating Patients With Uveal Melanoma With Liver Metastases [EARLY_Phase 1]
Early-phase 1 trial evaluating the combination of radioembolization with ipilimumab for uveal melanoma with liver metastases has been termin…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma [Phase 1]
Phase 1 trial evaluating ADI-PEG 20 plus cisplatin in metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2016-02-11Clinical Trial Update: Genasense, Carboplatin, Paclitaxel (GCP) Combination in Uveal Melanoma [Phase 2]
Phase 2 study evaluating Genasense (oblimersen) with carboplatin and paclitaxel in uveal melanoma was terminated, with results posted in 201…
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CLINICAL_TRIALS trial_result · 2015-06-01Clinical Trial Update: Halt Growth of Liver Tumors From Uveal Melanoma With Closure of Liver Artery Following Injection of GM-CSF [Phase 2]
A Phase 2 trial tested halting growth of liver tumors from uveal melanoma by hepatic artery closure after GM-CSF injection; the study has co…
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: Treatment With Intravitreal Avastin for Large Uveal Melanomas [NA]
A completed clinical trial update reported results for intravitreal bevacizumab (Avastin) in large uveal melanomas.
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: New Biopsy Technique for Uveal Melanoma
The clinical trial NCT01924923 evaluated a new biopsy technique for uveal melanoma. The study status is COMPLETED.
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CLINICAL_TRIALS research · 2014-12-03Clinical Trial Update: A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma [Phase 2]
This clinical trial update describes a Phase 2 study of sorafenib in chemonaive metastatic uveal melanoma. The current status is listed as U…
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CLINICAL_TRIALS trial_result · 2014-10-03Clinical Trial Update: Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma [Phase 2]
A Phase 2 trial of vorinostat in patients with metastatic or unresectable melanoma has completed, with results posted in 2014. The study enc…
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CLINICAL_TRIALS trial_result · 2014-02-21Clinical Trial Update: Dendritic Cell Vaccination During Lymphoid Reconstruction [Phase 1]
Phase 1 trial of dendritic cell vaccination during lymphoid reconstruction for uveal melanoma and cutaneous melanoma has completed.
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma [Phase 2]
A Phase 2 trial evaluated a combination of temozolomide, thalidomide, and lomustine in patients with unresectable stage III or IV melanoma, …