Uveal Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Neoadjuvant/Adjuvant Trial of Darovasertib in Ocular Melanoma [Phase 2]
Phase 2 neoadjuvant/adjuvant trial of darovasertib in ocular melanoma has completed enrollment, with St Vincent's Hospital, Sydney listed as…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases [Phase 1]
Phase 1 trial evaluating stereotactic radiosurgery, NovoTTF-200M, and immune checkpoint inhibitors for melanoma brain metastases was termina…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Tebentafusp and Roginolisib in Uveal Melanoma to Prolong T-cell Homeostasis [Phase 1]
Phase 1 trial evaluating tebentafusp and roginolisib in metastatic uveal melanoma is currently recruiting to study effects on T-cell homeost…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma [Phase 2]
Phase 2 clinical trial update on the combination of binimetinib and belinostat for metastatic uveal melanoma. The study is currently active …
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma [Phase 1]
Phase 1 clinical trial of targeted alpha particle radiotherapy for metastatic uveal melanoma; the study is currently active but not recruiti…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma [Phase 1]
Phase 1 trial update reports proof of concept for TBio-4101 in combination with lymphodepleting chemotherapy and IL-2 for relapsed/refractor…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma [Phase 2]
A Phase 2 clinical trial is evaluating olaparib in combination with pembrolizumab for advanced uveal/ocular melanoma, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors [Phase 1]
A Phase 1 clinical trial evaluating a gene-modified immune cell therapy after a conditioning regimen for metastatic melanoma and other metas…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases [Phase 1]
This phase 1 study assessed pembrolizumab in combination with stereotactic radiosurgery for patients with brain metastases from melanoma or …
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Adjuvant Tebentafusp in High Risk Ocular Melanoma [Phase 3]
This update notes ongoing Phase 3 recruitment for adjuvant tebentafusp in high-risk uveal melanoma, sponsored by the European Organisation f…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: IKKb-matured, RNA-loaded Dendritic Cells for Metastasised Uveal Melanoma [Phase 1]
A Phase 1 study evaluating an IKKβ-matured, RNA-loaded dendritic cell therapy for metastatic uveal melanoma has completed. The trial investi…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma [Phase 3]
Phase 3 randomized trial in recruitment evaluating Belzupacap Sarotalocan (AU-011) versus sham control for primary indeterminate lesions or …
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Study Multicentre Evaluating the Effectiveness and Toxicity Sorafenib (Nexavar®) in Adult Patients With Uveal Melanoma and Metastatic Dissemination [Phase 2]
A Phase 2 multicenter study evaluating the effectiveness and toxicity of Sorafenib (Nexavar) in adults with uveal melanoma and metastatic di…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma [Phase 1]
Phase 1 trial of the modified virus VSV-IFNbetaTYRP1 in stage III-IV melanoma was terminated.
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma [Phase 3]
Phase 3 clinical trial evaluating dendritic cells combined with autologous tumor RNA for uveal melanoma has completed.
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: A Phase 1 Study of [225Ac]-FPI-1434 Injection [Phase 1]
A Phase 1 study of [225Ac]-FPI-1434 injection sponsored by Fusion Pharmaceuticals has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating LVGN3616 and LVGN6051±LVGN7409 with nab-paclitaxel or bevacizumab and cyclophosphamide in various metastatic solid …
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Dexamethasone Implant for Retinal Detachment in Uveal Melanoma [Phase 1]
A Phase 1 clinical trial evaluating a dexamethasone intravitreal implant for exudative retinal detachment associated with uveal melanoma has…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma [Phase 1, Phase 2]
This document updates on a Phase 1/2 clinical trial assessing different doses of BI-1607 in combination with pembrolizumab and ipilimumab fo…
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: SIR-Spheres® 90Y Microspheres Treatment of Uveal Melanoma Metastasized to Liver [Phase 2]
Phase 2 trial evaluating SIR-Spheres 90Y resin microspheres for liver metastases from uveal melanoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Taxoprexin® Treatment for Advanced Eye Melanoma [Phase 2]
Phase 2 trial update reports completion of Taxoprexin studies for advanced eye melanoma; the excerpt does not include efficacy or safety res…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Intrahepatic Delivery of SD-101 by Pressure-Enabled Regional Immuno-oncology (PERIO), With Checkpoint Blockade in Adults With Metastatic Uveal Melanoma [Phase 1]
Phase 1 trial evaluating intrahepatic delivery of SD-101 with checkpoint blockade for metastatic uveal melanoma in the liver has been termin…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Stereotactic Body Radiation Therapy and Aflibercept in Treating Patients With Uveal Melanoma [Phase 2]
A Phase 2 trial evaluating stereotactic body radiation therapy with aflibercept for uveal melanoma has been terminated, and results have bee…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Evaluation Interest of the Circulating Tumor DNA Dosage in Patient With Hepatic Metastatic Uveal Melanoma Candidate to Complete Resection (ct DNA R0) [NA]
A completed clinical trial sponsored by Institut Curie evaluated circulating tumor DNA levels as a biomarker in patients with hepatic metast…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Melphalan Chemoreduction for Ocular Melanoma [Phase 1, Phase 2]
Ongoing Phase 1/Phase 2 clinical trial evaluating melphalan chemoreduction for uveal melanoma, currently enrolling by invitation.