Uveal Melanoma
📧 Sign up to get email alerts when something new happens for Uveal Melanoma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating controllable PRAME-TCR therapy in patients with acute myeloid leukemia, myelodysplastic syndrome, or metastatic u…
-
CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Trial of Radiation and Gene Therapy Before Nivolumab for Metastatic Non-Small Cell Lung Carcinoma and Uveal Melanoma [Phase 2]
A Phase 2 trial evaluating radiation and gene therapy before nivolumab in metastatic non-small cell lung cancer and uveal melanoma was termi…
-
CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001) [Phase 2]
Phase 2 trial evaluating niraparib in BAP1- and DDR-deficient neoplasms including mesothelioma and uveal melanoma has completed with results…
-
FDA approval · 2023-08-14FDA Approved: HEPZATO KIT — Original Application (Delcath Systems, Inc.)
The FDA approved HEPZATO KIT, a lyophilized melphalan hydrochloride injection, for isolated hepatic perfusion in adults with unresectable li…
-
CLINICAL_TRIALS trial_result · 2022-12-06Clinical Trial Update: A Study of Concurrent Stereotactic Body Radiotherapy With Opdualag in Metastatic Uveal Melanoma [Phase 2]
Phase 2 trial update evaluating concurrent stereotactic body radiotherapy with Opdualag in metastatic uveal melanoma.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
FDA approval · 2022-11-29FDA Approved: KIMMTRAK — Supplemental Application (Immunocore Commercial LLC)
FDA approved a supplemental application for KIMMTRAK (tebentafusp) filed by Immunocore Commercial LLC.
-
CLINICAL_TRIALS trial_result · 2022-08-31Clinical Trial Update: Comparison Between Fotemustin to Intensive Surveillance in Patients With High Risk Uveal Melanoma [Phase 3]
A Phase 3 clinical trial comparing Fotemustine to intensive surveillance in high-risk uveal melanoma has completed.
-
CLINICAL_TRIALS trial_result · 2022-03-22Clinical Trial Update: Trial of Nivolumab in Combination With Ipilimumab in Subjects With Previously Untreated Metastatic Uveal Melanoma [Phase 2]
Phase 2 trial update evaluating nivolumab in combination with ipilimumab for previously untreated metastatic uveal melanoma has completed.
-
EMA approval · 2022-02-25New medicine for rare type of eye cancer
The EMA announces a new medicine addressing a rare eye cancer, marking an important regulatory milestone for an orphan indication.
-
FDA approval · 2022-01-25FDA Approved: KIMMTRAK — Original Application (Immunocore Commercial LLC)
FDA approved KIMMTRAK (tebentafusp) in an original application for adults with unresectable or metastatic uveal melanoma, marking the first …
-
CLINICAL_TRIALS trial_result · 2021-11-11Clinical Trial Update: A Phase II Study of BVD-523 in Metastatic Uveal Melanoma [Phase 2]
Phase II study of BVD-523 in metastatic uveal melanoma was terminated; results have been posted.
-
CLINICAL_TRIALS trial_result · 2021-09-17Clinical Trial Update: Phase I/II Study of AloCelyvir in Patients With Metastatic Uveal Melanoma [Phase 1, Phase 2]
Phase I/II clinical trial update for AloCelyvir in metastatic uveal melanoma is in early-phase stages with unknown status.
-
CLINICAL_TRIALS trial_result · 2021-09-14Clinical Trial Update: Safety and Efficacy of IMCgp100 Versus Investigator Choice in Advanced Uveal Melanoma [Phase 2]
A Phase 2 trial comparing IMCgp100 against investigator's choice in advanced uveal melanoma completed, with results posted in September 2021…
-
CLINICAL_TRIALS trial_result · 2021-09-01Clinical Trial Update: A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating an intra-patient escalation dosing regimen of IMCgp100 in advanced uveal melanoma has been completed with results…
-
CLINICAL_TRIALS trial_result · 2021-04-19Clinical Trial Update: Yttrium90, Ipilimumab, & Nivolumab for Uveal Melanoma With Liver Metastases [Phase 1, Phase 2]
Phase 1/2 trial exploring Yttrium-90 in combination with ipilimumab and nivolumab for uveal melanoma with liver metastases.
-
CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Nivolumab and Ipilimumab in Treating Patients With Metastatic Uveal Melanoma [Phase 2]
Phase 2 trial evaluating nivolumab and ipilimumab for metastatic uveal melanoma has completed and results have been posted.
-
CLINICAL_TRIALS trial_result · 2020-09-14Clinical Trial Update: Study Evaluating Single and Repeated Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma [Phase 1]
Phase 1 trial evaluating single and repeated intravitreal doses of ICON-1 in patients with uveal melanoma; study completed with results post…
-
CLINICAL_TRIALS trial_result · 2020-08-21Clinical Trial Update: Glembatumumab Vedotin in Treating Patients With Metastatic or Locally Recurrent Uveal Melanoma [Phase 2]
Phase 2 clinical trial evaluating glembatumumab vedotin in patients with metastatic or locally recurrent uveal melanoma has completed with r…
-
CLINICAL_TRIALS trial_result · 2020-02-24Clinical Trial Update: Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma [Phase 2]
Phase 2 clinical trial evaluating trametinib with or without GSK2141795 in metastatic uveal melanoma; results posted in 2020 and the trial i…
-
CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Nab-Paclitaxel and Bevacizumab or Ipilimumab as First-Line Therapy in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating nab-paclitaxel with bevacizumab or ipilimumab as first-line therapy in patients with unresectable stage IV melanoma…
-
CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: A Phase II Study of Sunitinib Versus Dacarbazine in the Treatment of Patients With Metastatic Uveal Melanoma [Phase 2]
Phase II trial comparing sunitinib to dacarbazine in metastatic uveal melanoma has completed.
-
CLINICAL_TRIALS trial_result · 2019-04-26Clinical Trial Update: Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial comparing cabozantinib-s-malate to temozolomide or dacarbazine in metastatic or unresectable uveal melanoma; completed with re…
-
CLINICAL_TRIALS trial_result · 2019-01-10Clinical Trial Update: Dexamethasone Intravitreal Implant for Treatment of Macular Edema After Plaque Radiotherapy of Uveal Melanoma [Phase 2]
Phase 2 clinical trial evaluating a dexamethasone intravitreal implant for macular edema following plaque radiotherapy in uveal melanoma; st…
-
CLINICAL_TRIALS trial_result · 2018-10-29Clinical Trial Update: Dacarbazine and Recombinant Interferon Alfa-2b in Treating Patients With Primary Uveal Melanoma With Genetic Imbalance [Phase 2]
Phase 2 clinical trial evaluating dacarbazine plus recombinant interferon alfa-2b in patients with primary uveal melanoma with genetic imbal…
-
CLINICAL_TRIALS withdrawal · 2018-07-18Clinical Trial Update: Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating Glembatumumab Vedotin in combination with nivolumab and ipilimumab for advanced, unresectable solid tu…