Systemic Sclerosis
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CLINICAL_TRIALS withdrawal · 2012-10-31Clinical Trial Update: Low-Dose Conditioning Followed by Donor Stem Cell Transplant in Treating Patients With Severe Systemic Sclerosis [Phase 2]
A Phase 2 trial evaluating low-dose conditioning followed by donor stem cell transplantation for severe systemic sclerosis has been withdraw…
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CLINICAL_TRIALS trial_result · 2012-10-23Clinical Trial Update: Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis [Phase 1]
This is a Phase 1 pharmacokinetics study evaluating how oral treprostinil is processed in patients with systemic sclerosis. It assesses abso…
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CLINICAL_TRIALS trial_result · 2012-08-28Clinical Trial Update: Sacroiliitis in Systemic Sclerosis
A clinical trial investigating sacroiliitis in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2012-08-17Clinical Trial Update: Imatinib in Systemic Sclerosis [Phase 1, Phase 2]
Phase 1/2 clinical trial of imatinib in systemic sclerosis completed with results posted in 2012.
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CLINICAL_TRIALS research · 2012-06-25Clinical Trial Update: Early, Simple and Reliable Detection of Pulmonary Arterial Hypertension (PAH) in Systemic Sclerosis (SSc)
A terminated clinical trial update about early, simple detection of pulmonary arterial hypertension in systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: Investigation of Coronary and Pulmonary Circulatory Parameters in Systemic Sclerosis
A completed clinical trial assessing coronary and pulmonary circulatory parameters in individuals with systemic sclerosis; results of the st…
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CLINICAL_TRIALS trial_result · 2012-05-08Clinical Trial Update: A Study to Evaluate Safety and Tolerability of Multiple Doses of MEDI-546 in Adult Subjects With Scleroderma [Phase 1]
This document reports the completion of a Phase 1 trial evaluating the safety and tolerability of multiple doses of MEDI-546 in adults with …
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CLINICAL_TRIALS research · 2012-03-14Clinical Trial Update: Empirical Comparative Study of Variation Blood Level Antibody Vitamin D at Scleroderma (SSc) Patients Compared Healthy Peoples [NA]
This clinical trial update describes an empirical study comparing blood Vitamin D levels in patients with systemic sclerosis (scleroderma) v…
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CLINICAL_TRIALS trial_result · 2012-03-07Clinical Trial Update: Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma [Phase 2]
A Phase 2 proof-of-concept trial of imatinib (Gleevec) in active diffuse systemic sclerosis (scleroderma) has been terminated.
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CLINICAL_TRIALS trial_result · 2012-02-29Clinical Trial Update: Safety Evaluation of Dasatinib in Subjects With Scleroderma Pulmonary Fibrosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety of dasatinib in patients with scleroderma-associated pulmonary fibrosis. The study has comp…
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CLINICAL_TRIALS trial_result · 2012-02-17Clinical Trial Update: Skin Biopsy Specimens as Biomarkers of Systemic Sclerosis and Response to Mycophenolate Mofetil
This completed clinical trial investigated skin biopsy biomarkers in systemic sclerosis and their relation to response to mycophenolate mofe…
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CLINICAL_TRIALS trial_result · 2011-09-23Clinical Trial Update: Early Therapy of Pulmonary Arterial Hypertension [NA]
This entry reports a completed clinical trial evaluating early therapy for pulmonary arterial hypertension. The trial was sponsored by the M…
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CLINICAL_TRIALS research · 2011-08-18Clinical Trial Update: AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 clinical trial update for AIMSPRO in established diffuse cutaneous systemic sclerosis (systemic sclerosis).
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Placebo Controlled Trial of Bosentan in Scleroderma Patients [Phase 2]
A phase 2 placebo-controlled trial of bosentan in patients with systemic sclerosis and pulmonary hypertension was terminated; results were p…
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CLINICAL_TRIALS trial_result · 2011-05-30Clinical Trial Update: Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome [Phase 3]
Phase 3 clinical trial update for moderate to severe dry eye syndrome, sponsored by Allergan, involving patients with Keratoconjunctivitis S…
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CLINICAL_TRIALS trial_result · 2011-03-31Clinical Trial Update: Mycophenolate Mofetil in Systemic Sclerosis [Phase 1]
Phase 1 clinical trial of mycophenolate mofetil for diffuse cutaneous systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2011-03-04Clinical Trial Update: Efficacy and Safety of Imatinib in Scleroderma [Phase 2]
Phase 2 trial of imatinib in systemic sclerosis and localized scleroderma has completed, with reported efficacy and safety outcomes.
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CLINICAL_TRIALS trial_result · 2010-09-16Clinical Trial Update: Premature Coronary Atherosclerosis in Scleroderma
A completed clinical trial update examining premature coronary atherosclerosis in systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2010-07-30Clinical Trial Update: Efficacy and Safety Study of GB-0998 for Treatment of Systemic Sclerosis [Phase 3]
Phase 3 trial evaluating the efficacy and safety of GB-0998 for systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2010-06-28Clinical Trial Update: Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases [Phase 4]
Phase 4 study assessing the safety and efficacy of an H1N1 vaccine in patients with rheumatic diseases. The current status of the trial is u…
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CLINICAL_TRIALS trial_result · 2010-05-25Clinical Trial Update: Oral Type I Collagen for Relieving Scleroderma [Phase 2]
Phase 2 clinical trial update evaluating oral type I collagen for systemic sclerosis (scleroderma) has completed.
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CLINICAL_TRIALS trial_result · 2010-05-10Clinical Trial Update: A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma [Phase 3]
A Phase 3 randomized trial evaluated the efficacy of tadalafil for Raynaud's phenomenon and digital ulcers in systemic sclerosis; the study …
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CLINICAL_TRIALS trial_result · 2010-03-09Clinical Trial Update: Sleep Disturbances and Pulmonary Artery/Aorta Diameter in Scleroderma Patient
A completed clinical trial update examining sleep disturbances and pulmonary artery to aorta diameter in a patient with systemic sclerosis (…
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CLINICAL_TRIALS trial_result · 2009-12-02Clinical Trial Update: Reduced Intensity Transplant in Medically Refractory Systemic Lupus Erythematosus (SLE) and Systemic Sclerosis (SSc) [Phase 1]
Phase 1 trial evaluating reduced-intensity transplant for medically refractory systemic lupus erythematosus and systemic sclerosis was termi…
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CLINICAL_TRIALS trial_result · 2009-10-27Clinical Trial Update: Influenza Vaccination in Patients With Scleroderma [Phase 4]
Phase 4 clinical trial update evaluating influenza vaccination in patients with systemic sclerosis (scleroderma).