Systemic Sclerosis
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CLINICAL_TRIALS trial_result · 2009-09-25Clinical Trial Update: Effect of Rosuvastatin on Systemic Sclerosis-related Pulmonary Hypertension [Phase 3]
A Phase 3 clinical trial evaluating rosuvastatin for systemic sclerosis-related pulmonary hypertension has completed.
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CLINICAL_TRIALS trial_result · 2009-09-03Clinical Trial Update: Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement [Phase 2]
This entry notes a Phase 2 trial evaluating low-dose oral imatinib for pulmonary involvement in systemic sclerosis (scleroderma); the trial …
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CLINICAL_TRIALS research · 2009-08-20Clinical Trial Update: Allogeneic Mesenchymal Stem Cells Transplantation for Systemic Sclerosis (SSc) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating allogeneic mesenchymal stem cell transplantation for systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2009-07-27Clinical Trial Update: The Effect of Physical Therapy on Raynaud's Phenomenon Secondary to Systemic Sclerosis [NA]
A completed clinical trial evaluated the effect of physical therapy on Raynaud's phenomenon in patients with systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2009-06-12Clinical Trial Update: Treatment of Early Systemic Sclerosis by Bosentan [Phase 1, Phase 2]
This clinical trial update reports that the Phase 1/2 study of bosentan for early systemic sclerosis was terminated.
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CLINICAL_TRIALS trial_result · 2009-01-07Clinical Trial Update: Sildenafil for Treatment of Digital Ulcers in Patients With Systemic Sclerosis [Phase 2]
Phase 2 clinical trial investigating sildenafil for the treatment of active digital ulcers in systemic sclerosis; the study status is comple…
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CLINICAL_TRIALS trial_result · 2008-09-03Clinical Trial Update: Phase II Pilot Study of Cyclophosphamide and Rabbit Anti-Thymocyte Globulin as Salvage Therapy in Patients With Diffuse Systemic Sclerosis [Phase 2]
Phase II pilot trial evaluating cyclophosphamide plus rabbit anti-thymocyte globulin as salvage therapy in diffuse systemic sclerosis has co…
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CLINICAL_TRIALS trial_result · 2008-08-22Clinical Trial Update: Effectiveness and Safety of Lidocaine for Scleroderma [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluated the effectiveness and safety of lidocaine for systemic sclerosis (scleroderma) and has completed.
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CLINICAL_TRIALS trial_result · 2008-06-30Clinical Trial Update: Trial of IC351 in Female Scleroderma Patients With Raynaud's and Sexual Dysfunction [Phase 2]
Phase 2 trial of IC351 in female Systemic Sclerosis patients with Raynaud's phenomenon and sexual dysfunction has completed.
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CLINICAL_TRIALS trial_result · 2008-06-25Clinical Trial Update: Recombinant Human Relaxin in the Treatment of Diffuse Scleroderma [Phase 3]
Phase 3 trial of Recombinant Human Relaxin for diffuse scleroderma (systemic sclerosis) has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Study of Silicone-Associated Connective Tissue Diseases
The NIAMS-sponsored study on silicone-associated connective tissue diseases has completed, focusing on systemic sclerosis and limited cutane…
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CLINICAL_TRIALS other · 2008-02-25Clinical Trial Update: Effect of Different Iloprost Doses on Symptoms in Systemic Sclerosis [Phase 2]
The Phase 2 trial evaluating different iloprost doses for systemic sclerosis has been terminated.
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CLINICAL_TRIALS trial_result · 2007-12-28Clinical Trial Update: Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients [Phase 1]
Phase 1 trial evaluating the safety and potential value of autologous bone marrow transplants after chemotherapy in patients with systemic s…
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CLINICAL_TRIALS trial_result · 2007-09-10Clinical Trial Update: Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis [Phase 2]
Phase 2 trial evaluating bosentan for skin fibrosis in systemic sclerosis has completed; the update notes the study status.
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FDA approval · 2007-06-01FDA Approved: TRACLEER — Supplemental Application (Actelion Pharmaceuticals US, Inc.)
FDA approved a supplemental application for TRACLEER (bosentan) filed by Actelion Pharmaceuticals US, Inc.
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CLINICAL_TRIALS trial_result · 2007-05-30Clinical Trial Update: Phase III Study of a Topical Gel Formulation for Treatment and Prevention of Raynaud's Phenomenon [Phase 3]
A Phase III trial evaluating a topical gel for treatment and prevention of Raynaud's phenomenon has completed, including participants with R…
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CLINICAL_TRIALS research · 2007-04-20Clinical Trial Update: Platelet Gel in Systemic Sclerosis [Phase 2, Phase 3]
A Phase 2/3 clinical trial investigating Platelet Gel for systemic sclerosis (scleroderma).
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CLINICAL_TRIALS research · 2007-03-29Clinical Trial Update: Non-Invasive Diagnostic and Functional Evaluation of Cardiac Involvement in Patients With Systemic Sclerosis
A clinical trial evaluating non-invasive diagnostic and functional methods to assess cardiac involvement in patients with systemic sclerosis…