Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2014-08-13Clinical Trial Update: Treatment and Prevention of Progression of Interstitial Lung Disease in Systemic Sclerosis
This clinical trial update discusses approaches to treating and preventing progression of interstitial lung disease in systemic sclerosis. T…
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CLINICAL_TRIALS trial_result · 2014-07-02Clinical Trial Update: High Dose Cyclophosphamide for Treatment of Scleroderma [Phase 3]
A Phase 3 trial evaluating high-dose cyclophosphamide for systemic sclerosis has completed enrollment and posted results.
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CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: Finger Hardness Measure in Scleroderma
A Mayo Clinic-sponsored trial assessing finger hardness as a biomarker in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: Small Intestinal Mucosal Abnormalities in Systemic Sclerosis Using Capsule Endoscopy
A completed clinical trial evaluating small intestinal mucosal abnormalities in systemic sclerosis using capsule endoscopy.
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CLINICAL_TRIALS trial_result · 2014-04-30Clinical Trial Update: Cyclophosphamide and rATG With Hematopoietic Stem Cell Support in Systemic Scleroderma [Phase 2]
Phase 2 trial evaluating cyclophosphamide and rabbit anti-thymocyte globulin with hematopoietic stem cell support in systemic sclerosis; res…
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CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine [Phase 2]
Phase 2 trial investigating oral treprostinil diethanolamine for digital ischemic lesions in systemic sclerosis (scleroderma) completed with…
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CLINICAL_TRIALS trial_result · 2014-02-19Clinical Trial Update: Hemodynamic Changes in Connective Tissue Disease
A completed clinical trial update investigating hemodynamic changes in systemic sclerosis (a connective tissue disease).
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: Open-Label Study of Oral Treprostinil in Digital Ulcers [Phase 2]
An open-label Phase 2 trial evaluating oral treprostinil for digital ulcers in systemic sclerosis was terminated, with results posted in Feb…
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Sildenafil Effect on Digital Ulcer Healing in sClerodErma SEDUCE STUDY [Phase 3]
A Phase 3 clinical trial (SEDUCE) investigating sildenafil for healing digital ulcers in systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2014-01-23Clinical Trial Update: Morbidity and Mortality Follow Up for the Scleroderma Lung Study
This release provides morbidity and mortality follow-up data from the Scleroderma Lung Study, presenting long-term outcomes for participants…
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CLINICAL_TRIALS research · 2013-11-08Clinical Trial Update: Development and Prevention of Severe Heart Disease in Systemic Sclerosis
This clinical trial update outlines ongoing efforts to prevent and manage severe heart disease in systemic sclerosis, including cardiac bloc…
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CLINICAL_TRIALS research · 2013-09-17Clinical Trial Update: Lysyl Oxidase, Semaphorin 7a and Semaphorin 3a in Patients With Systemic Sclerosis [NA]
This entry reports a clinical trial evaluating lysyl oxidase and semaphorin 7a/3a in patients with systemic sclerosis. The current trial sta…
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CLINICAL_TRIALS research · 2013-07-18Clinical Trial Update: Treprostinil Iontophoresis : a Pharmacodynamic and Pharmacokinetic Study [Phase 1, Phase 2]
Clinical trial update describing a pharmacodynamic and pharmacokinetic study of treprostinil administered by iontophoresis in systemic scler…
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CLINICAL_TRIALS trial_result · 2013-07-15Clinical Trial Update: Digital Ulceration
Clinical trial investigating digital ulcers in systemic sclerosis has completed.
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CLINICAL_TRIALS withdrawal · 2013-07-08Clinical Trial Update: Stress Echocardiography in the Detection of Pulmonary Arterial Hypertension in Systemic Sclerosis Patients
A clinical trial investigating stress echocardiography to detect pulmonary arterial hypertension in systemic sclerosis patients has been wit…
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FDA approval · 2013-07-01FDA Approved: TRACLEER — Supplemental Application (Actelion Pharmaceuticals US, Inc.)
The FDA approved a supplemental NDA for Tracleer (bosentan) submitted by Actelion Pharmaceuticals US, Inc.
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Pulmonary Involvement in Scleroderma: A Clinical Study of the Safety and Efficacy of Mycophenolate Mofetil in Scleroderma Patients With Lung Involvement [NA]
This completed clinical trial evaluated the safety and efficacy of mycophenolate mofetil in patients with systemic sclerosis (scleroderma) w…
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CLINICAL_TRIALS research · 2013-04-26Clinical Trial Update: Development and Prevention of Pulmonary Hypertension in Systemic Sclerosis
Clinical trial update on the development and prevention of pulmonary hypertension in systemic sclerosis; status is not provided.
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CLINICAL_TRIALS research · 2013-04-25Clinical Trial Update: Prevention and Treatment of Digital Ulcers in Systemic Sclerosis
An update on a clinical trial investigating prevention and treatment of digital ulcers in systemic sclerosis; the current trial status is un…
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CLINICAL_TRIALS trial_result · 2013-04-16Clinical Trial Update: Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-year Manometric Follow-up
Results of a five-year prospective, manometric follow-up study examining small bowel motor impairment in systemic sclerosis (scleroderma) ar…
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CLINICAL_TRIALS trial_result · 2013-03-22Clinical Trial Update: Randomised Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma [Phase 3]
A Phase 3 randomized trial evaluating tadalafil for Raynaud's phenomenon in patients with scleroderma has completed.
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CLINICAL_TRIALS research · 2013-03-19Clinical Trial Update: Effects of Intensive Aerobic and Muscle Endurance Exercise in Patients With Systemic Sclerosis - a Pilot Study [NA]
This clinical trial update describes a pilot study evaluating the effects of intensive aerobic and muscle endurance exercise in patients wit…
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CLINICAL_TRIALS trial_result · 2013-02-28Clinical Trial Update: Sonographic and Laboratory Evaluation of the Thyroid Gland in Patients With Systemic Sclerosis
This completed clinical trial evaluated sonographic and laboratory assessment of the thyroid gland in patients with systemic sclerosis, incl…
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CLINICAL_TRIALS trial_result · 2013-02-11Clinical Trial Update: Efficacy and Safety Study of p144 to Treat Skin Fibrosis in Systemic Sclerosis [Phase 2]
A Phase 2 study evaluating p144 for skin fibrosis in systemic sclerosis has completed, reporting efficacy and safety data. The sponsor is IS…
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CLINICAL_TRIALS trial_result · 2012-12-18Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplantation (NST) for Patients With Systemic Sclerosis [Phase 1]
A Phase 1 study evaluating allogeneic hematopoietic stem cell transplantation for systemic sclerosis has been terminated.