Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-01-08Clinical Trial Update: Scleroderma Lung: Role of Gastroesophageal Reflux, Microaspiration and Cough
A completed clinical trial update evaluating the role of gastroesophageal reflux, microaspiration, and cough in scleroderma lung.
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CLINICAL_TRIALS research · 2015-12-22Clinical Trial Update: Improvement of Hand Dysfunction by Arthritis in Systemic Sclerosis
Clinical trial update about a study on improving hand dysfunction in patients with systemic sclerosis and arthritis; the current status is u…
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CLINICAL_TRIALS withdrawal · 2015-12-02Clinical Trial Update: Evaluating Pulmonary Arterial Hypertension in Patients With Systemic Sclerosis [NA]
A clinical trial evaluating pulmonary arterial hypertension in patients with systemic sclerosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-12-02Clinical Trial Update: Evaluation of Pulmonary Doppler Signals in Patients With Systemic Sclerosis(SSc) [NA]
A clinical trial evaluating pulmonary Doppler signals in patients with Systemic Sclerosis and Pulmonary Hypertension has been withdrawn.
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CLINICAL_TRIALS research · 2015-11-17Clinical Trial Update: The CARRA Registry
The CARRA Registry study sponsored by Duke University has completed, documenting a broad range of juvenile rheumatic diseases, including Juv…
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CLINICAL_TRIALS trial_result · 2015-11-05Clinical Trial Update: A Study of RoActemra/Actemra (Tocilizumab) Versus Placebo in Patients With Systemic Sclerosis [Phase 3]
Phase 3 trial evaluating tocilizumab (RoActemra/Actemra) versus placebo in systemic sclerosis has completed and results were posted.
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CLINICAL_TRIALS research · 2015-11-05Clinical Trial Update: EFFECTS OF THE MICRO REINJECTION OF AUTOLOGOUS ADIPOSE TISSUE IN THE FACE OF PATIENTS WITH SYSTEMIC SCLEROSIS [NA]
Trial investigating the effects of microinjection of autologous adipose tissue in the face of patients with systemic sclerosis.
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CLINICAL_TRIALS withdrawal · 2015-11-02Clinical Trial Update: Systemic Sclerosis Clinical and Biomarker Study
Biogen's Systemic Sclerosis clinical and biomarker study has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-10-22Clinical Trial Update: Post Marketing Surveillance Study of Cuprimine
This clinical trial update covers a post-marketing surveillance study of Cuprimine (penicillamine) for systemic sclerosis. The study is no l…
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Safety and Tolerability of Pirfenidone in Participants With Systemic Sclerosis-Related Interstitial Lung Disease (SSc-ILD) (LOTUSS) [Phase 2]
A Phase 2 trial (LOTUSS) evaluated the safety and tolerability of pirfenidone in systemic sclerosis-related interstitial lung disease (SSc-I…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Immunoadsorption in Patients With Severe Systemic Sclerosis [NA]
The clinical trial update indicates that the immunoadsorption study in patients with severe systemic sclerosis has been terminated.
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: UVA1 Light for Treatment of Scleroderma and Similar Conditions [NA]
Completed clinical trial evaluating UVA1 light therapy for systemic sclerosis (scleroderma) and keloids.
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CLINICAL_TRIALS trial_result · 2015-04-24Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Abatacept in Patients With Diffuse Systemic Sclerosis (Scleroderma) [Phase 1, Phase 2]
Completed Phase 1/2 study evaluating abatacept for diffuse systemic sclerosis (scleroderma); results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Scleroderma Lung Disease [Phase 3]
Phase 3 trial for systemic sclerosis–associated lung disease has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders [Phase 1]
Completed Phase 1 pilot study evaluating total body irradiation with cyclophosphamide, anti-thymocyte globulin, and autologous CD34-selected…
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial update reports safety, tolerability, and pharmacokinetics data for CAT-192, a human anti-TGF-beta1 monoclon…
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CLINICAL_TRIALS research · 2015-02-05Clinical Trial Update: Genesis of Scleroderma: Role of Environmental Factors in 100 Patients With Scleroderma and 300 Controls
A completed observational study assessing the role of environmental factors in systemic sclerosis by comparing 100 patients with 300 control…
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CLINICAL_TRIALS trial_result · 2015-01-28Clinical Trial Update: Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients [Phase 3]
A Phase 3 trial evaluating macitentan for digital ulcers in systemic sclerosis was terminated, and results were posted in January 2015.
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients [Phase 3]
Macitentan was studied in a Phase 3 trial for treating digital ulcers in systemic sclerosis; results were posted January 6, 2015.
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CLINICAL_TRIALS research · 2014-11-27Clinical Trial Update: Effects of Probiotics on Gastrointestinal Symptoms and on the Immune System in Patients With Systemic Sclerosis [Phase 3]
Phase 3 clinical trial evaluating the effects of probiotics on gastrointestinal symptoms and immune system parameters in patients with syste…
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CLINICAL_TRIALS trial_result · 2014-11-13Clinical Trial Update: A Study of the Safety and Tolerability of MEDI-551 in Scleroderma [Phase 1]
This document summarizes the results of a Phase 1 study evaluating the safety and tolerability of MEDI-551 (inebilizumab) in patients with s…
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: A Rho-kinase Inhibitor (Fasudil) in the Treatment of Raynaud's Phenomenon [Phase 3]
Phase 3 clinical trial evaluating fasudil, a Rho-kinase inhibitor, for Raynaud's phenomenon (including scleroderma) has completed and posted…
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CLINICAL_TRIALS trial_result · 2014-10-27Clinical Trial Update: A Study Using The Experimental Drug Called Imatinib (Gleevec) in Subjects With Systemic Sclerosis [Phase 1, Phase 2]
This update covers a Phase 1/2 trial of Imatinib (Gleevec) in systemic sclerosis and alveolitis, with results posted after completion.
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Assessment of the Subcutaneous Reinjection of Human Autologous Adipose-derived Stromal Vascular Fraction (Celution® System) in the Hands of Patients Suffering From Systemic Sclerosis [NA]
Clinical trial update reporting the completion of a study evaluating subcutaneous reinjection of autologous adipose-derived stromal vascular…
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CLINICAL_TRIALS trial_result · 2014-08-27Clinical Trial Update: An Open-Label Study to Evaluate Biomarkers and Safety in Systemic Sclerosis Patients Treated With ABR-215757 (Paquinimod) [Phase 2]
An open-label Phase 2 trial evaluated biomarkers and safety of paquinimod (ABR-215757) in patients with systemic sclerosis. The study has co…