Systemic Lupus Erythematosus
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study [NA]
A Stanford-led clinical trial compares online 8-session cognitive behavioral therapy with a 1-session Empowered Relief program for chronic p…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users
Prospective registry evaluating maternal and infant outcomes in pregnant individuals exposed to anifrolumab for systemic lupus erythematosus…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Evaluate the Safety,Tolerability,Pharmacokinetics and Pharmacodynamics of Cenerimod in Adult Chinese Participants With Moderate-to-severe Systemic Lupus Erythematosus (SLE) [Phase 2]
A Phase 2 study is evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of cenerimod in adult Chinese participants wit…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus [Phase 3]
This clinical trial update reports on a Phase 3 study evaluating the safety and tolerability of Dapirolizumab Pegol in participants with Sys…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE) [Phase 2]
Phase 2 study Breakfree-SLE is evaluating CC-97540 (BMS-986353 / Zola-cel), a CD19-targeted NEX-T CAR T cell, in participants with active sy…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus [Phase 3]
An update on a Phase 3 trial of subcutaneous anifrolumab in adults with systemic lupus erythematosus. The study status is ACTIVE_NOT_RECRUIT…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA) [Phase 1]
This is a Phase 1 clinical trial update for LY4298445, recruiting in healthy participants and in individuals with systemic lupus erythematos…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE) [Phase 2]
Merck's Phase 2 WILLOW LTE trial evaluating M5049 for systemic lupus erythematosus (including cutaneous lupus subtypes) is currently active …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus [Phase 3]
An extension Phase 3 study evaluating the long-term safety and potential symptom improvement of litifilimab (BIIB059) in adults with systemi…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MTS109 in Patients With Refractory Autoimmune Diseases [EARLY_Phase 1]
A Phase 1 clinical trial evaluating MTS109 in adults with refractory autoimmune diseases is currently recruiting. The study includes systemi…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires
A clinical trial update evaluating whether gonadotropin-releasing hormone agonists can preserve ovarian function in women with systemic lupu…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Lupus Landmark Study: A Prospective Registry and Biorepository
A prospective lupus registry and biorepository is being established to collect clinical data and biospecimens from patients with systemic lu…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders [Phase 1, Phase 2]
Phase I/II trial of AD-PluReceptor plus tafasitamab-cxix with lymphodepleting chemotherapy in autoimmune disorders is currently recruiting, …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Immun4Cure Cohort of Autoimmune Diseases
Clinical trial update from University Hospital, Montpellier on the Immun4Cure cohort for autoimmune diseases (Rheumatoid Arthritis and Syste…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Patient-Centered Assessment of Symptoms and Outcomes
NCCIH-sponsored clinical trial update describes a study on patient-centered assessment of symptoms and outcomes for fatigue and cancer, curr…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases [Phase 4]
Phase 4 clinical trial assessing safety and immunogenicity of the live attenuated tetravalent Butantan-Dengue vaccine in autoimmune rheumati…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Phase I Study to Assess LBL-047 in Healthy Adults and Patients With Systemic Lupus Erythematosus [Phase 1]
A Phase 1 trial to assess the safety, tolerability, and pharmacokinetics of LBL-047 in healthy adults and in patients with Systemic lupus er…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Safety and Preliminary Efficacy of HN2302 in Patients With Autoimmune Diseases [Phase 1]
Phase 1 clinical trial update on HN2302 assessing safety and preliminary efficacy in autoimmune diseases, including systemic lupus erythemat…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of CC312 for Relapsed/Refractory Autoimmune Diseases [EARLY_Phase 1]
This is an early-phase 1 study evaluating CC312 for relapsed/refractory autoimmune diseases, including systemic lupus erythematosus, idiopat…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA [Phase 1]
A Phase 1a/b tolerability update on the investigational drug NTR-1011 in healthy adults and patients with systemic lupus erythematosus or rh…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus [Phase 3]
Nipocalimab is being studied in a Phase 3 trial for adults with moderate to severe systemic lupus erythematosus and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
A Bristol-Myers Squibb-sponsored clinical trial is recruiting participants with active systemic lupus erythematosus who have inadequate resp…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in Anifrolumab Users [Phase 4]
This Phase 4 clinical trial registry is evaluating maternal, infant, and lactation outcomes in patients using anifrolumab for systemic lupus…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: First-in-Human Study of ISH0613: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics [Phase 1]
First-in-human Phase 1 study of ISH0613 to assess safety, tolerability, pharmacokinetics, and pharmacodynamics in healthy subjects and indiv…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: SELECT-SLE: Biomarker-Guided CAR-T Target Selection for Refractory Lupus [Phase 1, Phase 2]
This clinical trial update describes SELECT-SLE, a Phase 1/2 study of biomarker-guided CAR-T target selection for refractory systemic lupus …