Systemic Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: SAPHNELO Systemic Lupus Erythematosus Japan Post-Marketing Surveillance (PMS)
Post-marketing surveillance update for SAPHNELO (anifrolumab) in systemic lupus erythematosus in Japan; the PMS is active and not recruiting…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Characteristics and Disease Progression of Mixed Connective Tissue Disease and Systemic Lupus Erythematosus
This completed University of Miami study examined characteristics and disease progression in patients with mixed connective tissue disease a…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms. [Phase 2]
A Phase 2 study of PF-06823859 in adults with active lupus erythematosus with skin involvement has been terminated.
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: The Effect of Co-enzyme Q10 on the Clinical Outcome of Pediatric Patients With Systemic Lupus Erythematosus [Phase 2]
A completed Phase 2 clinical trial investigated the effect of Coenzyme Q10 on clinical outcomes in pediatric patients with systemic lupus er…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Longitudinal Study of Quality of Life and Activity in Systemic Lupus Erythematosus [NA]
This is a completed clinical trial update from Centre Hospitalier Universitaire Dijon. It reports on quality of life and activity in systemi…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: A Study of Telitacicept in Subjects With Childhood-onset Systemic Lupus Erythematosus [Phase 1]
This update notes the completion of a Phase 1 study evaluating Telitacicept in children with childhood-onset systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1) [Phase 3]
Novartis is conducting a Phase 3 trial (SIRIUS-SLE 1) to evaluate two regimens of ianalumab added to standard-of-care therapy in patients wi…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Phone-Based Based Walk With Ease Program for Adults With Arthritis [NA]
Completed clinical trial evaluating a phone-based Walk With Ease program for adults with arthritis, with results posted.
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Personalised Pharmacological Approach to the Tapering of Corticosteroid Doses in Systemic Lupus Patients Treated With Prednisone [NA]
A completed clinical trial evaluating a personalised approach to tapering corticosteroid doses in systemic lupus erythematosus patients trea…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Safety and Efficacy of ES-NK Cell Injection in the Treatment of Refractory Lupus Nephritis: an Early Clinical Study [EARLY_Phase 1]
Early Phase 1 clinical trial assessing the safety and potential efficacy of ES-NK cell injections for refractory lupus nephritis; the study …
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: A Clinical Study of Dual-Target, Universal CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus [Phase 1]
Phase 1 study update indicates Hangzhou Qihan Biotech is actively recruiting participants for a dual-target universal CAR-T cell therapy for…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: The HOP-STEP Intervention: Improving Maternal Health in Women With Lupus sIRB [NA]
This entry provides an update on the HOP-STEP intervention trial aimed at improving maternal health in women with Systemic Lupus Erythematos…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE [Phase 3]
A Phase 3 clinical trial evaluated the efficacy, safety, tolerability, and pharmacokinetics/pharmacodynamics of emapalumab in children and a…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Prognostic Factors for Fatigue in Patients With Systemic Lupus Erythematosus
This completed clinical trial identifies prognostic factors associated with fatigue in systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory Diseases [NA]
A completed clinical trial update reporting an in vitro study of interleukin-2 muteins on regulatory T cells in patients with autoimmune, al…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Transition to Adulthood Through Coaching and Empowerment in Rheumatology [NA]
A completed study evaluating a coaching and empowerment program to help youths with juvenile rheumatic diseases transition to adulthood.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Assessing the Impact of Herbal Supplement on Fatigue and Disease Activity in SLE: Results From an 8-Week Randomized Trial [NA]
The study reports results from an 8-week randomized trial evaluating a herbal supplement's effect on fatigue and disease activity in systemi…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Phase 2 Trial of Mesenchymal Stem Cells in Systemic Lupus Erythematosus (MiSLE) [Phase 2]
Phase 2 trial evaluating mesenchymal stem cells for systemic lupus erythematosus has completed enrollment (MiSLE).
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Whole Health Empowerment for Endotypes of Lupus: Improving Quality of Life in SLE [NA]
A completed clinical trial evaluating whole-health empowerment to improve quality of life in systemic lupus erythematosus. The study investi…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Study of Ultra-Fast BCMA/CD70 CAR-T Therapy for Refractory SLE [Phase 1]
Phase 1 clinical trial evaluating an ultra-fast BCMA/CD70 CAR-T therapy for refractory Systemic Lupus Erythematosus; the study is currently …
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Clinical Study on Targeted CD19CAR-T Therapy for Autoimmune Diseases [EARLY_Phase 1]
A Phase 1 targeted CD19 CAR-T therapy trial for autoimmune diseases has been suspended.
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Study During Pregnancy of Expression of miRNAs in RA or SLE
A completed clinical trial from University Hospital Strasbourg studying the expression of microRNAs during pregnancy in patients with rheuma…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Anti-CD19 CAR-T Cell Therapy in Participants With Moderate to Severe Active Systemic Lupus Erythematosus [NA]
A clinical trial evaluating anti-CD19 CAR-T cell therapy for moderate to severe active systemic lupus erythematosus has been suspended.
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: A Comparative Study of the Efficacy and Safety of Telitacicept and Belimumab in the Treatment of Systemic Lupus Erythematosus Involving Multiple Units, Based on Previous Data.
This clinical trial update compares the efficacy and safety of telitacicept versus belimumab for systemic lupus erythematosus, based on prio…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus [Phase 3]
A Phase 3 clinical trial update evaluating litifilimab (BIIB059) for systemic lupus erythematosus, focusing on safety and potential symptom …