Systemic Lupus Erythematosus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of Families With Twins or Siblings Discordant for Rheumatic Disorders
A completed clinical trial studying families with twins or siblings discordant for rheumatic disorders, conducted by NIEHS. The study includ…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Treatment of Systemic Lupus Erythematosus (SLE) With N-acetylcysteine [Phase 2]
A Phase 2 trial is evaluating N-acetylcysteine for systemic lupus erythematosus. The study status is active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study of D-2570 in Patients With Active Systemic Lupus Erythematosus (SLE) [Phase 2]
A Phase 2 clinical trial evaluating D-2570 for active systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis [Phase 1]
This clinical trial update reports on evaluating the safety and tolerability of baricitinib in patients with Hyper-IgE syndrome due to STAT3…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE) [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, cellular kinetics, pharmacodynamics, and efficacy of the cellular therapy P-CD19…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Anifrolumab Malignancy and Serious Infections Study
AstraZeneca is recruiting for a clinical study of Anifrolumab in systemic lupus erythematosus, with monitoring for malignancy and serious in…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic Diseases [Phase 1]
Phase 1 clinical trial evaluating the safety of CD19-targeted CAR-T cell therapy produced at Gustave Roussy for adults with severe and refra…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE) [Phase 2]
This clinical trial update notes a Phase 2 study to evaluate different doses of BI 3000202 in people with systemic lupus erythematosus, whic…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Subclinical Atherosclerosis in Juvenile Systemic Lupus Erythematosus
A ClinicalTrials.gov listing for a study on subclinical atherosclerosis in juvenile systemic lupus erythematosus, currently not recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO [Phase 1]
Phase 1 trial evaluating nivolumab in patients with autoimmune disorders and advanced cancers; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Alnuctamab for Refractory SLE (LATTE Study) [Phase 1]
A Phase 1 LATTE study evaluating alnuctamab for refractory systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: INTERSTELLAR - International Study Evaluating Lupus Outcomes After Anifrolumab Real World Use
A real-world evidence study (INTERSTELLAR) evaluating lupus outcomes in patients treated with anifrolumab, sponsored by AstraZeneca.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Clinica Study of SCTC21C in Participants With Systemic Lupus Erythematosus [Phase 1, Phase 2]
Clinical trial entry for SCTC21C in systemic lupus erythematosus, a Phase 1/2 study that is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study [NA]
A Stanford-led clinical trial compares online 8-session cognitive behavioral therapy with a 1-session Empowered Relief program for chronic p…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users
Prospective registry evaluating maternal and infant outcomes in pregnant individuals exposed to anifrolumab for systemic lupus erythematosus…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Evaluate the Safety,Tolerability,Pharmacokinetics and Pharmacodynamics of Cenerimod in Adult Chinese Participants With Moderate-to-severe Systemic Lupus Erythematosus (SLE) [Phase 2]
A Phase 2 study is evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of cenerimod in adult Chinese participants wit…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus [Phase 3]
This clinical trial update reports on a Phase 3 study evaluating the safety and tolerability of Dapirolizumab Pegol in participants with Sys…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE) [Phase 2]
Phase 2 study Breakfree-SLE is evaluating CC-97540 (BMS-986353 / Zola-cel), a CD19-targeted NEX-T CAR T cell, in participants with active sy…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus [Phase 3]
An update on a Phase 3 trial of subcutaneous anifrolumab in adults with systemic lupus erythematosus. The study status is ACTIVE_NOT_RECRUIT…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA) [Phase 1]
This is a Phase 1 clinical trial update for LY4298445, recruiting in healthy participants and in individuals with systemic lupus erythematos…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE) [Phase 2]
Merck's Phase 2 WILLOW LTE trial evaluating M5049 for systemic lupus erythematosus (including cutaneous lupus subtypes) is currently active …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus [Phase 3]
An extension Phase 3 study evaluating the long-term safety and potential symptom improvement of litifilimab (BIIB059) in adults with systemi…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MTS109 in Patients With Refractory Autoimmune Diseases [EARLY_Phase 1]
A Phase 1 clinical trial evaluating MTS109 in adults with refractory autoimmune diseases is currently recruiting. The study includes systemi…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires
A clinical trial update evaluating whether gonadotropin-releasing hormone agonists can preserve ovarian function in women with systemic lupu…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Lupus Landmark Study: A Prospective Registry and Biorepository
A prospective lupus registry and biorepository is being established to collect clinical data and biospecimens from patients with systemic lu…