Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating LVGN3616 and LVGN6051±LVGN7409 with nab-paclitaxel or bevacizumab and cyclophosphamide in various metastatic solid …
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Recognition of Circulating Tumor DNA in Soft Tissue Sarcoma
This clinical trial update notes ongoing recruitment for a study evaluating circulating tumor DNA as a biomarker in soft tissue sarcoma.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma
An update on a clinical trial recruiting to evaluate outcomes after limb-sparing surgery for soft tissue sarcoma.
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Colorectal Resections in Patients With Retroperitoneal Sarcoma
This clinical trial update describes a study on colorectal resections in patients with retroperitoneal soft tissue sarcoma, which is current…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Preoperative Moderately Fractionated IMRT for Locally Extremity or Trunk Sarcoma (SPARE-03) [Phase 2]
This update reports the completion of the SPARE-03 Phase 2 trial evaluating preoperative moderately fractionated IMRT for soft tissue sarcom…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Preoperative IMRT With Concurrent Apatinib for Localised Extremity or Trunk Sarcoma （SPARE-02） [Phase 2]
Phase 2 trial assessing preoperative intensity-modulated radiotherapy with concurrent apatinib for localized soft tissue sarcoma of the extr…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Molecular Profiling of Advanced Soft-tissue Sarcomas [Phase 3]
A Phase 3 trial examining molecular profiling for advanced soft-tissue sarcomas is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Preoperative IMRT With Concurrent Anlotinib for Localised Extremity or Trunk Sarcoma （SPARE-01） [Phase 2]
Phase 2 clinical trial evaluating preoperative intensity-modulated radiotherapy with concurrent Anlotinib for localized soft tissue sarcoma …
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Preoperative Ultra-hypofractionated Radiotherapy Followed by Surgery for Retroperitoneal Sarcoma (FUSION-01) [NA]
This entry reports the ongoing FUSION-01 trial evaluating preoperative ultra-hypofractionated radiotherapy followed by surgery for retroperi…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Minibeam Radiation Therapy With Tungsten Slit Collimator for the Treatment of Recurrent or Metastatic Skin or Soft Tissue Tumors, MBRT1 Trial [NA]
The MBRT1 trial is evaluating minibeam radiation therapy with a tungsten slit collimator for recurrent or metastatic skin and soft tissue tu…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Feasibility Trial of Preoperative 5-Day Hypofractionated Radiotherapy for Primary Soft Tissue Sarcoma [NA]
This is a feasibility study evaluating a preoperative 5-day hypofractionated radiotherapy regimen for primary soft tissue sarcoma; the trial…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO Trial [Phase 2]
Phase 2 neoadjuvant trial evaluating pembrolizumab with eftilagimod alpha and radiotherapy in soft tissue sarcoma; the study is currently ac…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update for Habitat Escalated Adaptive Therapy (HEAT) with neoadjuvant radiation in soft tissue sarcoma; the study is …
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Fluorescence-Guided Optimization of Sarcoma Margins [NA]
A clinical trial evaluating fluorescence-guided techniques to optimize sarcoma surgical margins. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: CINSARC Signature and Correlation With Hemotherapy Efficacy in Soft-tissue Sarcomas. A Biomarker Study. [NA]
This clinical trial update reports on a biomarker study investigating the CINSARC gene expression signature and its correlation with chemoth…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Preventive Application of Single-use Negative Pressure Wound Therapy (sNPWT) in the Postoperative Course of Radiotreatated Limb Sarcoma Surgery [NA]
This clinical trial update indicates that a study is currently recruiting to evaluate the preventive use of single-use negative pressure wou…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia. [NA]
A clinical trial evaluating the Diffusing Alpha-emitters Radiation Therapy (DaRT) device for treating skin cancer, oral mucosal cancer, and …
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Retreatment With Intratumoral Diffusing Alpha Radiation Emitters [NA]
A completed clinical trial evaluating retreatment with intratumoral diffusing alpha radiation emitters for skin cancer, oral cavity mucosal …
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI [Phase 2]
Phase 2 trial evaluating dostarlimab for locally advanced or metastatic dMMR/MSI cancers excluding colorectal and endometrial, across multip…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma [Phase 2]
A Phase 2 trial of nab-paclitaxel plus gemcitabine for recurrent or refractory sarcoma has completed and posted results.
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas [Phase 1]
Phase 1 clinical trial evaluating the combination of BOLD-100 with doxorubicin in advanced soft tissue sarcoma; study status is not yet recr…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Prospective Study to Evaluate Patient Reported Outcomes (PRO) During Rechallenge With Trabectedin in Sarcoma Patients
A prospective study evaluating patient-reported outcomes during rechallenge with trabectedin in soft tissue sarcoma patients has been termin…
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CLINICAL_TRIALS withdrawal · 2025-12-01Clinical Trial Update: Study Evaluating Pembrolizumab +/- Olaparib in TLS Positive Selected Resectable STS Followed by Adjuvant Pembrolizumab [Phase 2]
A Phase 2 clinical trial evaluating pembrolizumab with or without olaparib in TLS-positive selected resectable soft tissue sarcoma, followed…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma [Phase 1]
Phase 1 clinical trial update on in vivo lung perfusion for sarcoma with pulmonary metastases; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Prospective Phase I/II Study Evaluating the Safety and Efficacy of Preoperative Carbon Ion Radiotherapy in Patients With Soft Tissue Sarcoma : The SARCOMA-01 Trial by the Severance sARCOma Multidisciplinary Team [NA]
A prospective Phase I/II clinical trial evaluating preoperative carbon ion radiotherapy for soft tissue sarcoma, sponsored by Yonsei Univers…