Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Phase 1 Study of SON-1010 in Adult Patients With Advanced Solid Tumors [Phase 1]
Phase 1 trial update for SON-1010 in adults with advanced solid tumors, including soft tissue sarcoma; the study is currently active but not…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: 68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue Sarcomas [NA]
A clinical trial evaluating 68Ga-DOTATATE PET/CT for the diagnosis of soft tissue sarcoma is currently recruiting at the Ohio State Universi…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Impact of Locoregional Treatment of Soft Tissue Sarcoma on Status of Patients Aged 70 Years and Over [NA]
An ongoing clinical trial evaluating locoregional treatment of soft tissue sarcoma in patients aged 70 years and older; the study status is …
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma. [Phase 2]
Clinical trial evaluating dose-escalated, hypofractionated definitive proton radiotherapy for patients with inoperable soft tissue sarcoma (…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating TGFβ-imprinted, ex vivo expanded universal donor NK cell infusions in combination with gemcitabine and d…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma [Phase 1, Phase 2]
A first-in-human study of ADCE-D01 in soft tissue sarcoma (metastatic or unresectable) is in Phase 1/2 and currently recruiting.
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update evaluating hypofractionated, 3-week preoperative radiotherapy using proton or photon therapy for localized sof…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy [Phase 1]
Phase 1 clinical trial evaluating a vaccine therapy in combination with pembrolizumab for adults with various solid tumors that have failed …
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas [Phase 2]
This Phase 2 clinical trial compares hypofractionated versus conventional fractionated radiotherapy in soft tissue sarcoma and is currently …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Biomarkers of Resiliency In Childhood Cancer Surgery
Clinical trial update from Mayo Clinic on biomarkers of resiliency in pediatric cancer surgery, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Sarcomas and DDR-Inhibition; a Combined Modality Study [Phase 1]
A Phase 1 trial investigating DDR inhibition in soft tissue sarcoma was terminated.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma [Phase 1]
Phase 1 clinical trial evaluating HER2-targeted CAR T cells in combination with checkpoint blockade for advanced sarcoma; recruitment is ong…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization [Phase 1]
Phase 1 trial evaluating an RNA-lipid particle vaccine intended to sensitize tumors to anti-PD-1 therapy in patients with melanoma and soft …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Short Course Of Preoperative Radiotherapy in Head and Neck-, Trunk- and Extremity Soft Tissue Sarcomas [NA]
This document provides a status update on a trial evaluating a short course of preoperative radiotherapy for soft tissue sarcomas in the hea…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Radiation Therapy Before Surgery for Localized, Resectable Soft Tissue Sarcoma of the Extremity and Superficial Trunk [Phase 2]
A Mayo Clinic phase 2 trial evaluating preoperative radiation therapy for localized, resectable soft tissue sarcoma of the extremities and s…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma [NA]
A Mayo Clinic-sponsored clinical trial is studying individualized prehabilitation to improve recovery and surgical outcomes for patients wit…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Prospective, Multicenter, Open-label, Single-arm Phase II Clinical Study Evaluating the Efficacy and Safety of Spatially Fractionated Radiotherapy Combined With the PraG Strategy for the Treatment of Soft Tissue Sarcoma [Phase 2]
This document notes a Phase II clinical trial evaluating spatially fractionated radiotherapy combined with the PraG strategy for soft tissue…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Neoadjuvant Intralesional Injection of Talimogene Laherparepvec [Phase 2]
A Phase 2 neoadjuvant trial evaluating intralesional talimogene laherparepvec for soft tissue sarcoma is currently active but not recruiting…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS) [Phase 2]
Phase 2 trial evaluating an immuno-oncology combination as first-line treatment for soft tissue sarcomas; currently recruiting.
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue Sarcoma [Phase 1]
This update describes a Phase 1 trial evaluating Zanzalintinib in combination with ipilimumab and nivolumab for metastatic soft tissue sarco…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors [Phase 1]
A Phase 1 trial evaluating in situ immunomodulation using CDX-301, CDX-1140, and Poly-ICLC with radiation therapy in patients with unresecta…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma [Phase 1]
A Phase 1 trial evaluating tazemetostat with doxorubicin as frontline therapy for advanced epithelioid sarcoma has been terminated.
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors [Phase 1, Phase 2]
This phase 1/2 clinical trial update reports results for selpercatinib in pediatric participants with advanced solid tumors and primary CNS …
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Surgical Timing After Preoperative Hypofractionated Radiotherapy for Localized Extremity and Trunk Soft Tissue Sarcoma [NA]
This clinical trial update notes the status of a study evaluating surgical timing after preoperative hypofractionated radiotherapy for local…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE) [Phase 2]
This clinical trial update outlines a Phase 2 study (TNT-HYPE) to test the feasibility of total neoadjuvant treatment with HYPErthermia in p…