Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Update: Molecular Profiling of Advanced Soft-tissue Sarcomas [Phase 3]
Phase 3 trial assessing molecular profiling in advanced soft-tissue sarcomas has completed.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma [Phase 2]
An ongoing Phase 2 trial is evaluating the combination of envafolimab with doxorubicin and ifosfamide for advanced soft tissue sarcoma, asse…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease [Phase 1]
Phase 1 trial evaluating bevacizumab and temsirolimus alone or with valproic acid or cetuximab in patients with advanced or metastatic malig…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Gemcitabine and Docetaxel With or Without Bevacizumab (Onbevzi) for Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update evaluating gemcitabine and docetaxel with or without bevacizumab (Onbevzi) for soft tissue sarcoma; the study …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients
An upcoming St. Jude clinical study aims to deeply phenotype gait deficits in orthopedic issues seen in pediatric cancer patients, currently…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma [NA]
An update on a clinical trial evaluating adaptive proton therapy for pediatric solid tumors and Hodgkin lymphoma. The trial is currently not…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a MEK inhibitor in combination with a PD-L1 inhibitor for locally advanced or metastatic soft tissue s…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Combination of Nivolumab Plus Relatlimab in Patients With Advanced or Metastatic Soft-tissue Sarcoma: a Proof-of-concept Randomized Phase II Study [Phase 2]
A completed Phase 2 randomized trial evaluating the combination of nivolumab and relatlimab in advanced or metastatic soft-tissue sarcoma.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas (TORNADO) [Phase 2]
Phase 2 clinical trial evaluating neoadjuvant chemotherapy plus retifanlimab in patients with resectable soft tissue sarcoma.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 clinical trial update describes testing the combination of ipilimumab and nivolumab with or without cabozantinib in adults with ad…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Lenvatinib and Pembrolizumab in People With Advanced Soft Tissue Sarcoma [Phase 2]
Phase 2 trial evaluating the combination of lenvatinib and pembrolizumab in adults with advanced soft tissue sarcoma; the study is currently…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors [Phase 1]
Phase I study update for the radiopharmaceutical [177Lu]Lu-DFC413 in patients with various solid tumors, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma [Phase 1]
This clinical trial update describes a Phase 1 study assessing neoadjuvant ADI-PEG 20 plus ifosfamide and radiotherapy in soft tissue sarcom…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma [NA]
This clinical trial update notes that a study evaluating targeted oligometastatic radiation for pediatric and young adult patients with soft…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC) [Phase 3]
Phase 3 clinical trial ARGSARC evaluating ADI-PEG 20 or placebo plus gemcitabine and docetaxel in previously treated leiomyosarcoma (soft ti…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas [Phase 2]
Phase 2 trial evaluating doxorubicin in combination with dual checkpoint blockade for metastatic or advanced soft tissue sarcoma. The study …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma [Phase 2]
The document notes a Phase 2 trial evaluating Zanzalintinib in combination with pembrolizumab for select subtypes of advanced or metastatic …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Pre-operative Hypofractionated Proton Therapy [NA]
A clinical trial at Johns Hopkins is recruiting to evaluate pre-operative hypofractionated proton therapy for soft tissue sarcoma.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Pembrolizumab With Intratumoral Injection of Clostridium Novyi-NT [Phase 1]
Phase 1 clinical trial evaluating pembrolizumab in combination with intratumoral injection of Clostridium novyi-NT across multiple cancer ty…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Organoid-based Sensitivity-guided Chemotherapy for Advanced / Refractory Pediatric Tumors [NA]
Clinical trial update describing an organoid-based, sensitivity-guided chemotherapy approach studied for advanced or refractory pediatric so…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Agnostic Therapy in Rare Solid Tumors [Phase 2]
A Phase 2 trial of an agnostic therapy for multiple rare solid tumors is currently recruiting. The study lists a broad set of tumor types ac…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Brief Title Mechanisms of Cancer-Related Pain and Opioid Use Among Adolescents and Young Adult Sarcoma Survivors: Pilot Feasibility Study
This clinical trial update describes a pilot feasibility study investigating mechanisms of cancer-related pain and opioid use among adolesce…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) [Phase 1]
Phase 1 clinical trial update for a B7-H3–targeted autologous CAR-T cell therapy (3CAR) in pediatric solid tumors, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) [Phase 2]
Phase 2 update from the Pediatric MATCH trial describes targeted therapies matched to tumor genetics in pediatric patients with relapsed or …
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Pharmacologic Interaction Between Ifosfamide and Aprepitant in Treated Patients With Soft Tissue Sarcoma [Phase 4]
Phase 4 trial assessing the pharmacologic interaction between ifosfamide and aprepitant in treated patients with soft tissue sarcoma; study …