Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations [Phase 2, Phase 3]
An ongoing DETERMINE trial (arm 06) investigates capmatinib for MET-dysregulated cancers, with Phase 2/3 testing and current recruitment.
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CLINICAL_TRIALS withdrawal · 2025-11-21Clinical Trial Update: A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 trial evaluating BT-001 alone and in combination with pembrolizumab in metastatic or advanced solid tumors has been terminated.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas [Phase 2]
Phase 2 study of LN-145 (LN-145-S1) in relapsed or refractory ovarian cancer, triple-negative breast cancer, anaplastic thyroid cancer, oste…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
Phase 1 clinical trial update describing B7H3-targeted CAR T-cell therapy for recurrent/refractory pediatric solid tumors, including several…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma [Phase 2]
A Phase II trial evaluating neoadjuvant atezolizumab with doxorubicin, concurrent atezolizumab with pre-operative radiation therapy, and adj…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: QL1706 in the Treatment of Advanced Bone and Soft Tissue Sarcoma [Phase 2]
An update on an ongoing Phase 2 trial evaluating QL1706 for advanced bone cancer and soft tissue sarcoma, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant Chemotherapy [Phase 3]
A Phase 3 trial comparing standard versus histotype-tailored neoadjuvant chemotherapy for localized high-risk soft tissue sarcomas of the ex…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating cabozantinib in combination with PD-1 and CTLA-4 inhibitors for metastatic soft tissue sarcoma; the study is curr…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases [Phase 1]
Phase 1 study evaluating aerosolized gemcitabine for treatment of various solid tumors, including those with pulmonary metastases; recruitme…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating selpercatinib for patients with activating RET gene alterations across adv…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of HFB301001 in Adult Patients With Advanced Solid Tumors [Phase 1]
The Phase 1 trial of HFB301001 in adults with advanced solid tumors has been terminated.
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study
The ALLUME Study is evaluating microwave ablation versus wedge resection for treatment of lung, sarcoma, and colorectal lesions, including v…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma [Phase 1]
First-in-human Phase 1 trial evaluating Attil12, a T-cell therapy with membrane-anchored IL-12, in patients with advanced soft tissue and bo…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA [Phase 2]
A Phase 2 trial evaluating niraparib in patients with soft tissue sarcoma who harbor tumor DNA alterations; the study is currently active bu…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma [Phase 2]
A Phase 2 study evaluating the combination of Etrumadenant and Zimberelimab in Dedifferentiated liposarcoma; the trial is currently active b…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: GRID Therapy for Extremity Soft Tissue Sarcoma [NA]
Clinical trial update on GRID therapy for extremity soft tissue sarcoma. The trial is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Financial Toxicity in Patients With Resected Soft Tissue and Bone Sarcomas
Clinical trial update for a study on financial toxicity in patients with resected soft tissue and bone sarcomas; recruitment is ongoing.
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CLINICAL_TRIALS other · 2025-10-07Clinical Trial Update: Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas [Phase 2]
A Phase 2 trial evaluating the combination of pembrolizumab and cabozantinib in advanced soft tissue sarcomas, including Ewing sarcoma, oste…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: A Multicenter, Single-arm, Prospective Phase II Clinical Study of Epalrotokewali Combined With Eribulin, Anlotinib, and Radiotherapy for the Treatment of Patients With Advanced Soft Tissue Sarcoma. [Phase 2]
Phase II multicenter, single-arm trial evaluating Epalrotokewali combined with eribulin, anlotinib, and radiotherapy for advanced soft tissu…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology [Phase 4]
Phase 4 clinical trial comparing low molecular weight heparin versus aspirin for venous thromboembolism prophylaxis in orthopedic oncology, …
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating infusion of NY-ESO-1–specific TCR-engineered lymphocytes in patients with NY-ESO-1-expressing…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Benefit of Intensified Peri-operative Chemotherapy Within High-risk CINSARC Patients With Resectable Soft-tissue Sarcomas [Phase 3]
Phase 3 trial evaluating intensified peri-operative chemotherapy in high-risk CINSARC patients with resectable non-metastatic soft-tissue sa…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Immunotherapy Combined With Radiotherapy for Metastatic Sarcoma [EARLY_Phase 1]
An early-phase Phase 1 clinical trial evaluating immunotherapy in combination with radiotherapy for metastatic soft tissue sarcoma. The stud…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Clinical Trial to Treat Stage IV Cancer Patients [Phase 1]
Moonshot Antibodies announced a Phase 1 trial enrolling patients with Stage IV soft tissue sarcoma.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Digital Art Therapy for Young Cancer Survivors [NA]
This document reports on a clinical trial studying digital art therapy for young cancer survivors, which is currently recruiting.