Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients. [Phase 1]
Phase 1 clinical trial evaluating attIL12-TIL, a T cell therapy engineered with membrane-anchored IL-12, for advanced/metastatic soft tissue…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: 5-AminoLevulinic Acid Aided Resection Margins in Sarcoma [EARLY_Phase 1]
An early-phase 1 clinical trial at University of Colorado, Denver is evaluating whether 5-ALA can improve surgical resection margins in soft…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue Sarcoma [Phase 1]
Phase 1 study of olaparib with concomitant radiotherapy in locally advanced or unresectable soft-tissue sarcoma has been completed and resul…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions [Phase 1]
Phase I trial evaluating the safety and preliminary activity of combining gemcitabine with nab-sirolimus in adults with advanced Leiomyosarc…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS) [Phase 3]
APROMISS is a Phase III trial of combined anlotinib and catequentinib in advanced alveolar soft-part sarcoma, leiomyosarcoma, and synovial s…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients
Clinical trial update describing precision medicine approaches for neoadjuvant therapy in high‑risk sarcoma patients; currently recruiting.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs [Phase 2]
This clinical trial update describes a Phase 2 study evaluating reduced-dose postoperative radiation for soft tissue sarcoma of the arms and…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: First-in-man Clinical Trial of CEB-01 PLGA Membrane in Recurrent or Locally Advanced Retroperitoneal Soft Tissue Sarcoma [Phase 1]
CEBIOTEX announced the completion of its first-in-man Phase 1 trial of CEB-01 PLGA Membrane for locally advanced or recurrent soft tissue sa…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Short Course of Radiotherapy Prior to Surgery of Soft Tissue Sarcomas [NA]
A clinical trial is evaluating a short course of radiotherapy before surgery for soft tissue sarcoma, with recruitment currently ongoing.
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types [Phase 1, Phase 2]
This update reports a Phase 1/2 trial of atezolizumab plus tivozanib in several immunologically cold tumor types, with the study currently s…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Preoperative Hypofractionated RT + Immunotherapy & Surgery for Retroperitoneal Sarcoma (FUSION-02) [NA]
A clinical trial update for the FUSION-02 study evaluating preoperative hypofractionated radiotherapy with immunotherapy followed by surgery…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: An Electronic Health Record (EHR)-Based Comprehensive Bone and Soft Tissue Tumor Registry
An Electronic Health Record-based registry study from Ohio State University Comprehensive Cancer Center aims to collect data on bone and sof…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Clinical and Biological Activity of an Anti-PD-L1 (Atezolizumab) in Operable Localised Soft Tissue Sarcomas Patients to be Treated With Radiotherapy [Phase 2]
This phase 2 clinical trial evaluates the clinical and biological activity of the anti-PD-L1 antibody atezolizumab in patients with operable…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: HDM201 and Pazopanib in Patients With P53 Wild-type Advanced/Metastatic Soft Tissue Sarcomas [Phase 1, Phase 2]
Clinical trial update for HDM201 in combination with pazopanib in patients with P53 wild-type advanced/metastatic soft tissue sarcoma; Phase…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group [NA]
An ongoing clinical trial under the MIRAS project aims to perform multimodal immune characterization of rare soft tissue sarcomas and relate…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Improved Management of Soft Tissue Sarcomas Patients With an Optimized and Innovative Sorting Technology for Circulating Tumor Cells [NA]
A clinical trial update describing an optimized sorting technology for circulating tumor cells to improve management of soft tissue sarcoma;…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Bacterial Decolonization Plus Intraoperative Angiography for Soft Tissue Sarcomas Receiving Preoperative Radiotherapy (CONCERTO) [Phase 2]
A Phase 2 clinical trial assessing bacterial decolonization plus intraoperative angiography as part of management for soft tissue sarcomas r…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas [Phase 1]
Phase 1 clinical trial in pediatric relapsed/refractory sarcomas evaluating hypofractionated radiation in combination with B7-H3-CAR T cells…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Pediatric PET/MR Image Registry
A pediatric PET/MR image registry is currently recruiting to collect imaging data for soft tissue sarcoma, lymphoma, and osteosarcoma.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma
A ClinicalTrials.gov update outlines a study that uses intraoperative indocyanine green dye fluorescence angiography to guide tumor resectio…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: GISAR German Interdisciplinary Sarcoma Registry
GISAR is a German interdisciplinary sarcoma registry currently recruiting participants to collect data on various sarcoma types, including s…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours [Phase 1]
Phase 1 study evaluating AVA6000 in solid tumors, assessing safety, pharmacokinetics, and early efficacy; recruitment is ongoing across seve…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities [Phase 1]
A Phase 1 clinical trial evaluating the combination of gemcitabine and docetaxel with radiation for soft tissue sarcoma of the extremities h…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas [NA]
A completed clinical trial update examining diffusion-weighted MRI imaging in younger patients with newly diagnosed bone or soft-tissue sarc…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: HIFU Ablation of Soft Tissue Sarcoma [NA]
This clinical trial update reports ongoing recruitment for high-intensity focused ultrasound (HIFU) ablation in soft tissue sarcoma and desm…