Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Sorafenib and Dacarbazine in Soft Tissue Sarcoma [Phase 2]
A Phase 2 study evaluating the combination of sorafenib and dacarbazine in soft tissue sarcoma reported completed results in 2015, including…
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CLINICAL_TRIALS trial_result · 2015-11-18Clinical Trial Update: Post-Operative Chemoradiation for Extremity & Trunk Soft Tissue Sarcoma [Phase 1]
Phase 1 trial evaluating post-operative chemoradiation for extremity and trunk soft tissue sarcoma. Status: Completed.
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CLINICAL_TRIALS trial_result · 2015-11-03Clinical Trial Update: A Phase II Trial of Combined Hydroxychloroquine and Sirolimus in Soft Tissue Sarcoma [Phase 2]
A Phase II study of combining hydroxychloroquine and sirolimus for soft tissue sarcoma was terminated, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-27Clinical Trial Update: Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing gemcitabine with versus without rapamycin for advanced soft tissue sarcoma has completed.
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CLINICAL_TRIALS trial_result · 2015-10-27Clinical Trial Update: Doxorubicin vs. Trabectedin Plus Doxorubicin in Non Operable and/or Metastatic STS [Phase 2]
A Phase 2 trial comparing Doxorubicin alone versus Trabectedin plus Doxorubicin in non-operable and/or metastatic soft tissue sarcoma was te…
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FDA approval · 2015-10-23FDA Approved: YONDELIS — Original Application (Janssen Products, LP)
FDA approved the original application for Yondelis (trabectedin) from Janssen, establishing its initial US indication for soft tissue sarcom…
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: Phase II Study of Brivanib (BMS-582664) to Treat Multiple Tumor Types [Phase 2]
Phase II clinical trial of Brivanib (BMS-582664) across multiple tumor types has completed.
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: Combined Modality Treatment of Sarcomas of the Extremities [Phase 1]
A Phase 1 clinical trial evaluating combined modality treatment for soft tissue sarcomas of the extremities has completed.
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery [Phase 2]
Phase 2 trial evaluating selumetinib alone or with temsirolimus in patients with metastatic, recurrent, or locally advanced soft tissue sarc…
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FDA approval · 2015-09-22FDA Approved: VOTRIENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for VOTRIENT (pazopanib hydrochloride) from Novartis Pharmaceuticals, signaling an update to the dru…
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CLINICAL_TRIALS research · 2015-09-02Clinical Trial Update: Hyperthermia and Proton Therapy in Unresectable Soft Tissue Sarcoma [Phase 1, Phase 2]
This entry reports an ongoing Phase 1/Phase 2 trial at Kantonsspital Aarau evaluating hyperthermia with proton therapy for unresectable soft…
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CLINICAL_TRIALS research · 2015-08-21Clinical Trial Update: Long Term Neurotoxic Effects of Chemotherapy in Survivors of Bone and Soft Tissue Sarcomas. A Retrospective Study [NA]
A retrospective study evaluating long-term neurotoxic effects of chemotherapy in survivors of bone and soft tissue sarcomas.
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma [Phase 2]
Phase 2 trial evaluating the combination of temsirolimus and cixutumumab in locally advanced, metastatic, or recurrent soft tissue sarcoma a…
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating saracatinib (AZD0530) in adults with recurrent, locally advanced, or metastatic soft tissue sarcoma has completed…
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CLINICAL_TRIALS research · 2015-07-27Clinical Trial Update: Trabectedin and Irinotecan for Refractory Pediatric Sarcomas
Clinical trial update for pediatric refractory sarcomas exploring trabectedin in combination with irinotecan; current status is unknown.
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CLINICAL_TRIALS withdrawal · 2015-07-23Clinical Trial Update: Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma or Sarcoma [NA]
A clinical trial evaluating isolated limb perfusion with melphalan for stage IIIB-IV melanoma or soft tissue sarcoma has been withdrawn.
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CLINICAL_TRIALS research · 2015-07-09Clinical Trial Update: Chart Review of Treatments Received by Patients Diagnosed With Soft Tissue Sarcoma
A chart review of treatments received by patients diagnosed with soft tissue sarcoma; the observational study was terminated and results wer…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Trebananib in Treating Patients With Advanced Angiosarcoma That Cannot Be Removed by Surgery [Phase 2]
This Phase 2 trial evaluated trebananib in patients with advanced angiosarcoma unsuitable for surgical resection; the study has completed an…
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CLINICAL_TRIALS trial_result · 2015-06-19Clinical Trial Update: Phase IB Study of Gemcitabine, Docetaxel and Bevacizumab in Patients With Soft Tissue Sarcoma [Phase 1]
Phase IB trial evaluating gemcitabine, docetaxel, and bevacizumab for soft tissue sarcoma has completed.
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CLINICAL_TRIALS trial_result · 2015-05-25Clinical Trial Update: Phase 1b/2 Study of AMG 655 With Doxorubicin for the First-Line Treatment of Unresectable Soft Tissue Sarcoma [Phase 1, Phase 2]
Clinical Trial Update reports the completion of a Phase 1b/2 study evaluating AMG 655 in combination with doxorubicin as first-line therapy …
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: Phase II Study of Doxorubicin and Avastin® in Sarcoma. [Phase 2]
Phase II study of doxorubicin plus Avastin in sarcoma was terminated, with results posted in May 2015.
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CLINICAL_TRIALS trial_result · 2015-04-30Clinical Trial Update: Phase II Study of Ridaforolimus (MK-8669) With Metastatic Bone or Soft-tissue Sarcoma Patients (MK-8669-030 AM1) [Phase 2]
This is a completed Phase II clinical trial evaluating ridaforolimus (MK-8669) in patients with metastatic bone cancer or soft-tissue sarcom…
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood [Phase 2]
Phase 2 trial of imatinib mesylate in relapsed or refractory pediatric solid tumors has been completed.
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: BMS-247550 in Treating Patients With Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 study of BMS-247550 for advanced soft tissue sarcoma was terminated.
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CLINICAL_TRIALS trial_result · 2015-03-31Clinical Trial Update: Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma [Phase 2]
Phase 2 trial evaluating cixutumumab with temsirolimus in pediatric patients with recurrent or refractory sarcomas has been completed with r…