Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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EMA approval · 2016-09-16New treatment for patients with soft tissue sarcoma
EMA announces a new treatment option for patients with soft tissue sarcoma, indicating authorization or positive assessment for a new therap…
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: Evaluating Bacterial Response in Sarcoma Management Using Fluorescence Imaging
A completed clinical trial evaluating bacterial response in soft tissue sarcoma management using fluorescence imaging.
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CLINICAL_TRIALS trial_result · 2016-08-30Clinical Trial Update: Paclitaxel in Treating Patients With Locally Advanced or Metastatic Soft Tissue Angiosarcoma or Lymphangiosarcoma That Cannot Be Removed By Surgery [Phase 2]
Phase 2 trial update evaluating paclitaxel for locally advanced or metastatic soft tissue angiosarcoma or lymphangiosarcoma that cannot be r…
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: Safety Study of Dacarbazine and Bortezomib in Melanoma and Soft Tissue Sarcoma [Phase 1]
This update reports the completion of a Phase 1 safety study evaluating the combination of dacarbazine and bortezomib in patients with melan…
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CLINICAL_TRIALS trial_result · 2016-07-27Clinical Trial Update: Chemotherapy-induced Symptoms in Sarcoma Patients and the Impact of Tumor Burden
Clinical trial update reporting results from a completed study on chemotherapy-induced symptoms in sarcoma patients and how tumor burden inf…
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating vismodegib with RO4929097 targeting Hedgehog and Notch pathways in various advanced/metastatic soft tissue …
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CLINICAL_TRIALS research · 2016-07-15Clinical Trial Update: Magnetic Resonance Imaging or Ultrasound in Soft Tissue Tumors (MUSTT)
Update on the MUSTT trial evaluating MRI versus ultrasound for diagnosing soft tissue tumors, focusing on diagnostic accuracy, sensitivity, …
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: Biomarker Differences in Samples From Patients With Undifferentiated Sarcomas
This clinical trial update reports on biomarker differences observed in samples from patients with undifferentiated sarcomas, a subset of so…
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CLINICAL_TRIALS research · 2016-07-06Clinical Trial Update: Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis [Phase 3]
A Phase 3 trial comparing surgery with and without radiation therapy for primary soft tissue sarcoma of the retroperitoneum or pelvis has co…
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CLINICAL_TRIALS research · 2016-06-24Clinical Trial Update: Ifosfamide, Doxorubicin and Hypofractionated Radiotherapy in Neoadjuvant Sarcoma Treatment [Phase 2]
An update on a Phase 2 trial evaluating neoadjuvant therapy with ifosfamide, doxorubicin, and hypofractionated radiotherapy for soft tissue …
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CLINICAL_TRIALS trial_result · 2016-06-16Clinical Trial Update: Docetaxel, Gemcitabine and Pazopanib as Treatment for Soft Tissue Sarcoma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluated a combination of docetaxel, gemcitabine, and pazopanib for soft tissue sarcoma.
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CLINICAL_TRIALS trial_result · 2016-06-02Clinical Trial Update: A Trial of TH-302 in Combination With Doxorubicin Versus Doxorubicin Alone to Treat Patients With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma [Phase 3]
A Phase 3 trial comparing TH-302 plus doxorubicin to doxorubicin alone in patients with locally advanced unresectable or metastatic soft tis…
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CLINICAL_TRIALS withdrawal · 2016-05-26Clinical Trial Update: Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery [Phase 1]
The Phase 1 safety study of BLZ-100 in adults with soft tissue sarcoma undergoing surgery has been withdrawn.
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FDA approval · 2016-05-20FDA Approved: VOTRIENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for VOTRIENT (pazopanib hydrochloride) filed by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS research · 2016-05-18Clinical Trial Update: Biomarkers in Patients With Advanced Rhabdomyosarcoma
This completed clinical trial explored biomarkers in patients with advanced rhabdomyosarcoma.
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Biomarkers in Samples From Young Patients With Soft Tissue Sarcoma
Completed pediatric study evaluating biomarkers in tissue samples from young patients with soft tissue sarcoma.
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma [Phase 1]
This Phase 1 trial evaluated the combination of cixutumumab and doxorubicin in patients with unresectable, locally advanced, or metastatic s…
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CLINICAL_TRIALS trial_result · 2016-03-28Clinical Trial Update: An Open-label, Multicenter, Phase 2 Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Previously Treated Subjects With Advanced or Metastatic Soft Tissue Sarcoma (Study E7389-J081-217) [Phase 2]
Open-label, multicenter Phase 2 study evaluating eribulin mesylate in previously treated advanced or metastatic soft tissue sarcoma; the tri…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Known or Suspected Soft Tissue Sarcoma [Phase 2]
A Phase 2 study evaluating FluGlucoScan using 18F-fluorodeoxyglucose imaging in patients with known or suspected soft tissue sarcoma has bee…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS) [Phase 1, Phase 2]
Phase 1/2 trial of gemcitabine and docetaxel with pazopanib for neoadjuvant treatment in soft tissue sarcoma was terminated; results posted …
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CLINICAL_TRIALS trial_result · 2016-02-09Clinical Trial Update: Analysis of Blood During Surgery for Musculoskeletal Tumors
This clinical trial update reports on the analysis of blood during surgery for musculoskeletal tumors; the study NCT01682252 has been termin…
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CLINICAL_TRIALS withdrawal · 2016-02-03Clinical Trial Update: NY-ESO-1 Specific T Cells After Cyclophosphamide in Treating Patients With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma [Phase 1]
Phase 1 trial of NY-ESO-1–specific T cells after cyclophosphamide for advanced synovial sarcoma or myxoid liposarcoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: A Study of AVE8062 in Advanced-stage Soft Tissue Sarcoma After Failure of Anthracycline and Ifosfamide Chemotherapies [Phase 3]
A Phase 3 clinical trial evaluating AVE8062 in advanced soft tissue sarcoma after failure of anthracycline and ifosfamide has completed.
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Cathepsin Activatable Fluorescent Probe [Phase 1]
Phase 1 clinical trial evaluating a cathepsin-activatable fluorescent probe for imaging in soft tissue sarcoma and breast cancer; the study …
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: Quantitative MR Biomarkers for Sarcoma Treatment [NA]
This clinical trial update reports completed study results on quantitative MR biomarkers for soft tissue sarcoma treatment.