Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease [Phase 1]
Phase 1 trial evaluating bevacizumab and temsirolimus alone or with valproic acid or cetuximab in patients with advanced or metastatic malig…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Gemcitabine and Docetaxel With or Without Bevacizumab (Onbevzi) for Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update evaluating gemcitabine and docetaxel with or without bevacizumab (Onbevzi) for soft tissue sarcoma; the study …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients
An upcoming St. Jude clinical study aims to deeply phenotype gait deficits in orthopedic issues seen in pediatric cancer patients, currently…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma [NA]
An update on a clinical trial evaluating adaptive proton therapy for pediatric solid tumors and Hodgkin lymphoma. The trial is currently not…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas (TORNADO) [Phase 2]
Phase 2 clinical trial evaluating neoadjuvant chemotherapy plus retifanlimab in patients with resectable soft tissue sarcoma.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma [Phase 2]
A Phase 2 clinical trial update describes testing the combination of ipilimumab and nivolumab with or without cabozantinib in adults with ad…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors [Phase 1]
Phase I study update for the radiopharmaceutical [177Lu]Lu-DFC413 in patients with various solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma [NA]
This clinical trial update notes that a study evaluating targeted oligometastatic radiation for pediatric and young adult patients with soft…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC) [Phase 3]
Phase 3 clinical trial ARGSARC evaluating ADI-PEG 20 or placebo plus gemcitabine and docetaxel in previously treated leiomyosarcoma (soft ti…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas [Phase 2]
Phase 2 trial evaluating doxorubicin in combination with dual checkpoint blockade for metastatic or advanced soft tissue sarcoma. The study …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma [Phase 2]
The document notes a Phase 2 trial evaluating Zanzalintinib in combination with pembrolizumab for select subtypes of advanced or metastatic …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Pre-operative Hypofractionated Proton Therapy [NA]
A clinical trial at Johns Hopkins is recruiting to evaluate pre-operative hypofractionated proton therapy for soft tissue sarcoma.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Organoid-based Sensitivity-guided Chemotherapy for Advanced / Refractory Pediatric Tumors [NA]
Clinical trial update describing an organoid-based, sensitivity-guided chemotherapy approach studied for advanced or refractory pediatric so…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Agnostic Therapy in Rare Solid Tumors [Phase 2]
A Phase 2 trial of an agnostic therapy for multiple rare solid tumors is currently recruiting. The study lists a broad set of tumor types ac…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Brief Title Mechanisms of Cancer-Related Pain and Opioid Use Among Adolescents and Young Adult Sarcoma Survivors: Pilot Feasibility Study
This clinical trial update describes a pilot feasibility study investigating mechanisms of cancer-related pain and opioid use among adolesce…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) [Phase 1]
Phase 1 clinical trial update for a B7-H3–targeted autologous CAR-T cell therapy (3CAR) in pediatric solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma [Phase 3]
Phase 3 clinical trial evaluating perioperative chemotherapy in patients with CINSARC high-risk localized soft tissue sarcoma; currently rec…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating retifanlimab in combination with gemcitabine and docetaxel for advanced soft tissue sarcoma; the study…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Application of Contrast-enhanced Ultrasound in Monitoring Soft Tissue Sarcoma Response to Neoadjuvant Radiotherapy [EARLY_Phase 1]
An early-phase clinical trial at Thomas Jefferson University is evaluating contrast-enhanced ultrasound to monitor soft tissue sarcoma respo…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating adding abemaciclib to gemcitabine for soft tissue sarcoma; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST) [Phase 2]
A Phase 2 clinical trial update on rogaratinib (BAY 1163877) for FGFR1-4-altered advanced sarcoma and SDH-deficient gastrointestinal stromal…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Lurbinectedin + Doxorubicin In Leiomyosarcoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating lurbinectedin in combination with doxorubicin for advanced or metastatic soft-tissue sarcoma, including leiomyo…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: 5-Day Preoperative Radiation for Soft Tissue Sarcoma [Phase 2]
A Phase 2 clinical trial evaluating a 5-day preoperative radiation regimen for soft tissue sarcoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial [Phase 2]
This is a Phase 2 clinical trial (AXIOM) sponsored by the National Cancer Institute evaluating atezolizumab plus selinexor for alveolar soft…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery [Phase 2]
Clinical trial update for a Phase 2 study evaluating Talimogene laherparepvec with radiation therapy in newly diagnosed soft tissue sarcoma …