Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Functional and Mechanistic Characterization of Limb Ulcers in Patients With Sickle Cell Disease [NA]
A completed clinical trial presenting functional and mechanistic insights into limb ulcers in patients with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease [NA]
This completed clinical trial, sponsored by Hospices Civils de Lyon, studied muscle function and its biological and physiological determinan…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Function [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating non-myeloablative haploidentical hematopoietic cell transplantation for sickle cell disease, including…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Stem Cell Gene Therapy for Sickle Cell Disease [Phase 1, Phase 2]
An update on a Phase 1/Phase 2 stem cell gene therapy trial for sickle cell disease led by Donald B. Kohn; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease [Phase 3]
A Phase 3 study evaluating the long-term safety of inclacumab in sickle cell disease was terminated.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease [Phase 2]
A Phase 2 study of etavopivat in patients with sickle cell disease and thalassemia has completed.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease [Phase 1, Phase 2]
BEACON is a Phase 1/2 study evaluating BEAM-101 for severe sickle cell disease; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype [Phase 2]
A Phase 2 clinical trial evaluating SIL-8301 for control of hemolysis in a uniform sickle cell disease endotype is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: The Effect of Voxelotor on Cerebral Hemodynamic Response in Children With Sickle Cell Anemia [Phase 2]
Phase 2 trial evaluating voxelotor for cerebral hemodynamic response in children with sickle cell disease has been terminated.
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease
This entry describes a pilot neuroimaging study in sickle cell disease as part of The Boston Consortium to Cure Sickle Cell Disease. The tri…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: The Influence of micro-and Macro Vascular Dysfunction on Clinical Severity in Adults With Sickle Cell Anemia (SS) and Sickle Cell Hemoglobin C Disease (SC) [NA]
This completed clinical trial update examines how micro- and macrovascular dysfunction influences clinical severity in adults with sickle ce…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Study of Vitamin B12 Metabolism in Children With Sickle Cell Disease Exposed to MEOPA
This clinical trial is recruiting to study Vitamin B12 metabolism in children with sickle cell disease who are exposed to MEOPA (nitrous oxi…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Lipid Balance in Adult Sickle Cell Patients [NA]
This clinical trial update notes an ongoing study evaluating lipid balance in adults with sickle cell disease and dyslipidemia, currently ac…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease [NA]
A ClinicalTrials.gov update for a Boston Children's Hospital-sponsored study evaluating resilience-promoting interventions in adolescents an…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Prevention of Malnutrition in Children With Sickle Cell Disease [NA]
Clinical trial update indicating a study on preventing malnutrition in children with sickle cell disease is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Cohort Study of Sickle Cell Patients Evaluating Analgesic Strategies and Their Consequences
A completed cohort study in patients with Sickle Cell Disease evaluating various analgesic strategies and their consequences.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: SMYLS Multi-site Trial [NA]
The SMYLS multi-site trial for sickle cell disease is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET [Phase 2]
A Phase 2 trial at St. Jude is investigating the relationship between abnormal myocardial perfusion and diastolic dysfunction in sickle cell…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Sickle Cell Clinical Research and Intervention Program
A clinical trial update for the Sickle Cell Clinical Research and Intervention Program sponsored by St. Jude Children's Research Hospital, c…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises [Phase 3]
Pfizer's inclacumab in sickle cell disease patients experiencing vaso-occlusive crises has completed Phase 3 testing. Results have been post…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy [NA]
This ClinicalTrials.gov entry describes a pediatric stem cell transplant and cellular therapy trial evaluating a family health communication…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease [Phase 1, Phase 2]
A Phase 1/2 trial investigating ruxolitinib-enhanced haploidentical hematopoietic stem cell transplantation for children and young adults wi…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Oral Ketamine for Treatment of Vaso-Occlusive Pain [Phase 3]
This clinical trial update reports a Phase 3 study of oral ketamine for vaso-occlusive crisis pain in sickle cell disease, currently recruit…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Oxygen Therapy and Pregnancy in Sickle Cell Disease [Phase 3]
A Phase 3 trial assessing oxygen therapy for pregnant people with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD) [NA]
A clinical trial update reports on the feasibility and preliminary efficacy of Acceptance and Commitment Therapy (ACT) for sleep disturbance…