Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Predictors of Pain in Sickle Cell Disease [NA]
A Duke University-sponsored clinical trial is currently recruiting to identify predictors of pain in patients with Sickle Cell Disease and c…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: CHOICES3: Sickle Cell Disease Parenting CHOICES [NA]
Clinical trial update for CHOICES3 (Sickle Cell Disease Parenting CHOICES) sponsored by the University of Florida; the study involves sickle…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: STEM CELL MOBILIZATION WITH HIGH-DOSE PLERIXAFOR IN PATIENTS WITH SICKLE CELL DISEASE [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial evaluating high-dose plerixafor for stem cell mobilization in patients with sickle cell disease is not yet re…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Study to Understand the Genetic Risk of Developing an Immune Response After Blood Transfusions Among Individuals With Sickle Cell Disease
This recruiting study from the National Human Genome Research Institute aims to understand whether genetic factors influence the risk of dev…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders
Clinical trial update for ATHN Transcends, a natural history study of non-neoplastic hematologic disorders, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease
This clinical trial update describes the collection and storage of umbilical cord blood stem cells for treatment of sickle cell disease, and…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Gene Transfer for Sickle Cell Disease [Phase 1]
Phase 1 clinical trial update for a gene transfer therapy targeting sickle cell disease; trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease [Phase 1]
A Phase 1 clinical trial evaluating panobinostat (LBH589) in patients with sickle cell disease is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD) [Phase 1]
A Phase 1 study of genome-edited hematopoietic stem and progenitor cell therapy for sickle cell disease has been terminated.
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD) [Phase 1, Phase 2]
This document reports on an ongoing Phase 1/2 trial evaluating HBI-002, an oral carbon monoxide–releasing therapeutic, for sickle cell disea…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Hydroxyurea and EPO in Sickle Cell Disease [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the combination of hydroxyurea and erythropoietin in patients with sickle cell disease has completed wit…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain [NA]
A University of Pittsburgh-sponsored clinical trial is recruiting adolescents and emerging adults with sickle cell disease-related pain to a…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Hypoxic Red Blood Cells in Sickle Cell Anemia [NA]
A clinical trial update on hypoxic red blood cells for sickle cell disease sponsored by Hemanext; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders [Phase 1, Phase 2]
A Phase 1/2 clinical trial at Washington University evaluates reduced-intensity conditioning and familial HLA-mismatched bone marrow transpl…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Effect of Aquatic Exercises on Muscle Strength and Quality of Life in Children With Sickle Cell Anemia [NA]
This clinical trial update describes the effects of aquatic exercises on muscle strength and quality of life in children with sickle cell an…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702) [NA]
A completed clinical trial update reporting long-term outcomes of alternative donor allogeneic transplantation across multiple hematologic d…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: TMLI and Alemtuzumab for Treatment of Sickle Cell Disease [Phase 1]
Phase 1 trial evaluating total marrow irradiation with alemtuzumab conditioning for sickle cell disease, sponsored by City of Hope Medical C…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: A Study on the Effect of Etavopivat on Heart Rhythm in Healthy Participants [Phase 1]
Phase 1 study of etavopivat assessing heart rhythm in healthy participants has completed; the trial also lists sickle cell disease and thala…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Hyperbaric Oxygen Therapy in Sickle Cell Pain [NA]
This trial evaluated hyperbaric oxygen therapy for pain management in sickle cell disease during vaso-occlusive crises. The study status is …
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Oxbryta® Product Registry An Observational Study Designed to Evaluate the Effect of Oxbryta in Individuals With SCD
Pfizer's Oxbryta (voxelotor) product registry observational study in individuals with sickle cell disease was terminated, and results have b…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Research Study Investigating How Well NDec Works in People With Sickle Cell Disease [Phase 2]
This document notes the completion of a Phase 2 clinical trial evaluating NDec in people with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: A Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese Participants [Phase 1]
Phase 1 study evaluating a single dose of etavopivat in healthy Chinese participants has completed.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease [Phase 3]
A Phase 3 clinical trial evaluating lidocaine as an opioid-sparing treatment for vaso-occlusive crises in sickle cell disease; the study is …
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises [NA]
A clinical trials registry entry reports ongoing recruitment for a study evaluating virtual reality devices as an adjunct to standard care f…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Development and Adaptation of I-STRONG for SCD [NA]
Emory University reports that the development and adaptation of I-STRONG for sickle cell disease has completed and results have been posted.