Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: The Montreal Cognitive Assessment.Test in Adults With Sickle Cell Disease [NA]
The trial evaluating the Montreal Cognitive Assessment in adults with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: CS-206 in Patients With Sickle Cell Disease [EARLY_Phase 1]
CS-206 is an investigational drug being evaluated in an early-phase 1 clinical trial for sickle cell disease, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Early Life Exposures Among Children With Sickle Cell Disease [NA]
The document reports a clinical trial examining early life exposures in children with Sickle Cell Disease and notes that the study is curren…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Predictors and Outcomes in Patients With Sickle Cell Disease
A completed clinical trial update detailing predictors and outcomes in patients with sickle cell disease. Sponsor: St. Jude Children's Resea…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease [Phase 1]
A Phase 1 clinical trial update evaluating the safety and tolerability of escalating doses of fostamatinib in subjects with stable sickle ce…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Multicenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations
A multicenter observational study assessing myocardial iron overload in three transfused populations has completed, focusing on patients wit…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels [Phase 1, Phase 2]
NHLBI-sponsored Phase 1/2 clinical trial is evaluating repeat peripheral blood stem cell transplantation for patients with sickle cell disea…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Serial Assessment of Fertility Experiences
Clinical trial update for a study titled 'Serial Assessment of Fertility Experiences' in sickle cell anemia, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies [Phase 1]
Phase 1 clinical trial evaluating hematopoietic stem cell BCL11A enhancer gene editing for severe sickle cell disease and beta-thalassemia, …
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Assessing Physical Function in Sickle Cell Patients Taking Voxelotor [Phase 2]
A Phase 2 clinical trial is evaluating the impact of voxelotor on physical function in patients with Sickle Cell Disease and is currently ac…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Zinc for Infection Prevention in Sickle Cell Anemia-2 (ZIPS-2) [Phase 2, Phase 3]
The ZIPS-2 trial evaluating zinc for infection prevention in sickle cell disease has completed its Phase 2/Phase 3 study.
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: SCD Stem Cell Mobilization and Apheresis Using Motixafortide [Phase 1]
Phase 1 clinical trial evaluating Motixafortide to mobilize stem cells and perform apheresis in patients with sickle cell disease, sponsored…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Cooperative Assessment of Late Effects for SCD Curative Therapies
A clinical trial update announcing recruitment for a cooperative study to assess late effects of curative therapies in sickle cell disease, …
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Imatinib for Pain in Sickle Cell Anemia [Phase 1, Phase 2]
A Phase 1/2 trial evaluating imatinib for pain in Sickle Cell Disease was terminated, and results have been posted.
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease [Phase 1, Phase 2]
A Phase I/II clinical trial of ITU512 in healthy participants and sickle cell disease patients is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: MULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease [NA]
A multi-site feasibility study is evaluating MUSIc Therapy to improve quality of life in people with sickle cell disease; the trial is curre…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: A Long-term Follow-up Study in Patients Who Received BEAM-101
A long-term follow-up study of patients who received BEAM-101 is ongoing, with the trial currently recruiting to assess long-term outcomes i…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease [Phase 2]
A Phase 2 clinical trial is evaluating HLA-haploidentical stem cell transplantation to treat clinically aggressive sickle cell disease; curr…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Trans-auricular Nerve Stimulation as an Innovative Approach to the Treatment of Pain in Pediatric Patients Suffering From Sickle Cell Disease [NA]
A study is evaluating trans-auricular nerve stimulation to treat pain in pediatric sickle cell disease patients. The trial is currently recr…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Opioid Prescribing in the Emergency Department for Sickle Cell Disease
A completed clinical trial from Centre Hospitalier Universitaire de Nīmes studied opioid prescribing in the emergency department for sickle …
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study on Use of Omega-3 Fatty Acids to Improve Outcomes in Individuals With Sickle Cell Disease [NA]
A clinical trial update notes a study evaluating omega-3 fatty acids to improve outcomes in individuals with sickle cell disease; the study …
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity [Phase 3]
Phase 3 trial assessing L-Arginine in children with sickle cell disease and increased tricuspid regurgitant jet velocity has completed.
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CLINICAL_TRIALS withdrawal · 2026-01-22Clinical Trial Update: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Oral GSK4172239D Compared With Placebo in Sickle Cell Disease Participants Aged 18 to 50 Years [Phase 1]
Phase 1 study evaluating oral GSK4172239D versus placebo in adults with sickle cell disease was terminated.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Best Noninvasive Predictor of Renal Function in Assessing Adult Sickle Nephropathy
The clinical trial evaluating a noninvasive predictor of renal function in adults with sickle nephropathy has completed.
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease
Clinical trial update for VALID evaluating antibody responses to the measles vaccine in children with Sickle Cell Disease. The study is curr…