Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-06-02Clinical Trial Update: Carbon Monoxide Monitor for the Measurement of End-Tidal Carbon Monoxide Levels in Children With or Without Hemolysis [NA]
A completed clinical trial evaluating a carbon monoxide monitor for measuring end-tidal carbon monoxide levels in children with sickle cell …
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CLINICAL_TRIALS trial_result · 2014-05-28Clinical Trial Update: Curative Versus Disease-Modifying Therapies in Children With Severe Sickle Cell Disease
This ClinicalTrials.gov update reports on a completed study comparing curative approaches to disease-modifying therapies in children with se…
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CLINICAL_TRIALS trial_result · 2014-05-26Clinical Trial Update: Analysis of T-Cell Immune Reconstitution Following Allogeneic Hematopoietic BMT for Severe SCD
This clinical trial update describes analyses of T-cell immune reconstitution after allogeneic hematopoietic stem cell transplantation in pa…
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Extension Study of ACTIQ Treatment for Children and Adolescents With Breakthrough Pain [Phase 2]
A Phase 2 extension study evaluating ACTIQ for breakthrough pain in children and adolescents has completed.
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CLINICAL_TRIALS trial_result · 2014-04-21Clinical Trial Update: Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Children With Sickle Cell Disease [Phase 3]
Phase 3 trial evaluating the 13-valent pneumococcal conjugate vaccine in children with sickle cell disease has completed; results were poste…
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CLINICAL_TRIALS trial_result · 2014-03-21Clinical Trial Update: Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease [Phase 1, Phase 2]
This entry reports the completion status of a Phase 1/2 trial evaluating intermittent preventive treatment for malaria in people with sickle…
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CLINICAL_TRIALS trial_result · 2014-03-07Clinical Trial Update: Adenosine 2A Agonist Lexiscan in Children and Adults With Sickle Cell Disease [Phase 1]
Phase 1 trial assessing Lexiscan (regadenoson), an adenosine A2A receptor agonist, in children and adults with sickle cell disease; the stud…
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CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome [Phase 2]
A Phase 2 study (IMPACTS) evaluating varespladib, a phospholipase A2 inhibitor, for acute chest syndrome in sickle cell disease has complete…
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CLINICAL_TRIALS withdrawal · 2014-03-04Clinical Trial Update: A Study of Varespladib Infusion in Subjects With Sickle Cell Disease. [Phase 2]
Phase 2 clinical trial of varespladib infusion in sickle cell disease was terminated.
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CLINICAL_TRIALS trial_result · 2014-02-21Clinical Trial Update: Anticoagulation For Pulmonary Hypertension in Sickle Cell Disease [Phase 2]
Phase 2 trial evaluating anticoagulation for pulmonary hypertension in patients with sickle cell disease was terminated; results were posted…
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CLINICAL_TRIALS trial_result · 2013-12-11Clinical Trial Update: A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease [Phase 2]
Phase 2 results for prasugrel in pediatric participants with sickle cell disease have been posted following the completion of the trial.
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CLINICAL_TRIALS research · 2013-12-09Clinical Trial Update: Neutrophil Extracellular Traps and Sickle Cell Disease
This update describes a clinical trial examining the role of neutrophil extracellular traps in sickle cell disease, with the trial status cu…
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes [Phase 2]
Phase 2 trial update of an allogeneic mixed chimerism stem cell transplant using Campath (alemtuzumab) for hemoglobinopathies and bone marro…
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CLINICAL_TRIALS withdrawal · 2013-10-28Clinical Trial Update: Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis [Phase 2]
Phase 2 study of MP4CO for vaso-occlusive crises in sickle cell disease has been withdrawn. Sponsor Sangart reported the study status as wit…
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CLINICAL_TRIALS trial_result · 2013-09-17Clinical Trial Update: SALT: Alternative Donor Bone Marrow and Cord Blood Transplantation for High Risk Sickle Cell Disease [EARLY_Phase 1]
Early Phase 1 SALT trial evaluating alternative donor bone marrow and cord blood transplantation for high-risk sickle cell disease. The stud…
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CLINICAL_TRIALS trial_result · 2013-08-19Clinical Trial Update: Safety Study of MP4CO in Adult Sickle Cell Patients [Phase 1]
Phase 1 safety study of MP4CO in adults with sickle cell disease has completed; this update summarizes the trial status and safety assessmen…
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CLINICAL_TRIALS trial_result · 2013-08-16Clinical Trial Update: Simvastatin (Zocor) Therapy in Sickle Cell Disease [Phase 1, Phase 2]
This update reports results from a Phase 1/2 clinical trial evaluating simvastatin (Zocor) in sickle cell disease, with results posted in 20…
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CLINICAL_TRIALS trial_result · 2013-08-13Clinical Trial Update: MAST - Magnesium for Sickle Cell Acute Crisis in Children [Phase 3]
Phase 3 trial assessing magnesium sulfate for acute sickle cell crisis in children has completed.
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CLINICAL_TRIALS trial_result · 2013-08-07Clinical Trial Update: Future of Spermatogenesis in Men With Sickle Cell Disease Medically Treated [Phase 4]
Phase 4 clinical trial update noting completion of a study evaluating spermatogenesis in men with sickle cell disease who are being treated …
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CLINICAL_TRIALS withdrawal · 2013-08-07Clinical Trial Update: Dipyridamole/Magnesium To Improve Sickle Cell Hydration [Phase 2]
Phase 2 trial of dipyridamole with magnesium to improve hydration in sickle cell disease was withdrawn.
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CLINICAL_TRIALS research · 2013-08-02Clinical Trial Update: Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) [Phase 2, Phase 3]
Clinical trial update noting the completion of the INOSTA study evaluating inhaled nitric oxide for acute chest syndrome in sickle cell dise…
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CLINICAL_TRIALS trial_result · 2013-07-31Clinical Trial Update: Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial [Phase 2]
Phase 2 trial evaluating arginine therapy for vaso-occlusive pain episodes in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2013-07-30Clinical Trial Update: Psychometric Evaluation of the IPPAQ in Pediatric Patients With Sickle Cell Disease Hospitalized With Vasoocclusive Pain
The clinical trial evaluated the psychometric properties of the IPPAQ instrument in pediatric patients with sickle cell disease hospitalized…
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CLINICAL_TRIALS trial_result · 2013-07-30Clinical Trial Update: Assessing Function in Pediatric Patients With Sickle Cell Disease
The clinical trial assessing function in pediatric patients with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2013-07-30Clinical Trial Update: Validation of the Sickle Cell Disease Pain Burden Interview
Completed study validating the Sickle Cell Disease Pain Burden Interview as a tool to measure pain impact in sickle cell disease.