Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-25Clinical Trial Update: Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE) [Phase 3]
Phase 3 trial updating sickle cell disease with a focus on cardiovascular risk through red cell exchange therapy (SCD-CARRE).
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CLINICAL_TRIALS trial_result · 2026-08-04Clinical Trial Results: Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease [NA]
Clinical trial results evaluating the effectiveness of a computerized tool (PAINRelieveIt) to help manage pain in sickle cell disease; resul…
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CLINICAL_TRIALS trial_result · 2026-07-28Clinical Trial Results: Hyperbaric Oxygen Therapy in Sickle Cell Pain [NA]
Clinical trial results evaluate hyperbaric oxygen therapy for vaso-occlusive crisis in sickle cell disease; results have been posted after c…
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CLINICAL_TRIALS trial_result · 2026-06-30Clinical Trial Results: Gerofit Exercise Intervention for Older Adults With Sickle Cell Disease (SICKLE-FIT Study) [NA]
Results from the Gerofit exercise intervention trial in older adults with sickle cell disease have been completed and posted.
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CLINICAL_TRIALS trial_result · 2026-06-10Clinical Trial Results: A Study to Learn About Sickle Cell Disease In Adult Patients
Clinical trial results for a study on sickle cell disease in adults completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-06-03Clinical Trial Update: Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE) [Phase 3]
Phase 3 clinical trial update for the SCD-CARRE study investigating red cell exchange to address cardiovascular risk in sickle cell disease.
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Results: Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507) [Phase 2]
Phase 2 trial evaluating haploidentical bone marrow transplantation in patients with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2026-04-28Clinical Trial Results: Pilot Study PBSCT With TCRab Depletion For Hemoglobinopathies [NA]
Pilot study results for peripheral blood stem cell transplantation with TCRab depletion in hemoglobinopathies were completed and results pos…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat [Phase 1, Phase 2]
An ongoing extension study evaluating long-term safety, tolerability, pharmacokinetics, and pharmacodynamics of mitapivat in adults with sta…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Transcranial Photobiomodulation Treatment in Patients With Sickle Cell Disease [NA]
An update on a clinical trial evaluating transcranial photobiomodulation for sickle cell disease, sponsored by St. Jude Children's Research …
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat [Phase 1, Phase 2]
This clinical trial update reports on the safety, tolerability, pharmacokinetics, and pharmacodynamics of long-term mitapivat dosing in adul…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
This clinical trial update notes the completion of a study investigating secondary pulmonary hypertension in adults with sickle cell disease…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD) [Phase 2]
Phase 2 trial evaluating crovalimab as adjunct therapy to prevent vaso-occlusive episodes in sickle cell disease has completed, reporting on…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Functional Ovarian Reserve in Sickle Cell Disease
A clinical trial update shows that the study on functional ovarian reserve in individuals with sickle cell disease is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Study of the Effect of Etavopivat on Cerebral Hemodynamic Response in Children With Sickle Cell Disease [Phase 2]
This clinical trial evaluated the effect of etavopivat on cerebral hemodynamic responses in children with sickle cell disease; the Phase 2 s…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study [Phase 4]
A Phase 4 rollover study evaluating crizanlizumab in sickle cell disease patients who completed a prior Novartis-sponsored crizanlizumab tri…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Intravenous Gammaglobulin for Sickle Cell Pain Crises [Phase 1, Phase 2]
Phase 1 and Phase 2 clinical trials evaluating intravenous immunoglobulin for pain crises in sickle cell disease have completed.
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD) [Phase 1]
Phase 1b open-label study of DISC-3405 in participants with Sickle cell disease is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: The Feasibility of the Pray Until Something Happens (PUSH) Intervention-OUTPATIENT [NA]
Completed outpatient feasibility study evaluating the Pray Until Something Happens (PUSH) intervention for sickle cell disease.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Screening for Renal Complications in Children and Young Adults With Major Sickle Cell Disease [NA]
A clinical trial examining screening for renal complications in children and young adults with major sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: A Long-term Follow-up Study in Participants Who Received CTX001 [Phase 3]
A long-term follow-up update on participants who received CTX001 in a Phase 3 study, reporting safety and durability data for beta-thalassem…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: GBT021601-022: A Study of GBT021601 in Participants With Sickle Cell Disease (SCD) [Phase 2, Phase 3]
Pfizer's GBT021601 study in sickle cell disease (Phase 2/3) has been terminated and results have been posted.
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD) [Phase 3]
Phase 3 clinical trial update on the safety and efficacy of CTX001 in pediatric patients with severe sickle cell disease; the study is curre…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Safety and Efficacy of Gene Therapy of the Sickle Cell Disease by Transplantation of an Autologous CD34+ Enriched Cell Fraction That Contains CD34+ Cells Transduced ex Vivo With the GLOBE1 Lentiviral Vector Expressing the βAS3 Globin Gene in Patients With Sickle Cell Disease (DREPAGLOBE) [Phase 1, Phase 2]
Phase 1/2 trial update on safety and efficacy of autologous CD34+ cells transduced with the GLOBE1 lentiviral vector expressing βAS3 globin …
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: PASS of Xromi Comparing Safety and Effectiveness in Children Under 2 Years With Sickle Cell Disease [PRECISE PASS]
This update describes a post-authorization safety study (PASS) of Xromi evaluating safety and effectiveness in children under 2 with sickle …