Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia [Phase 1, Phase 2]
This Clinical Trials update reports on a Phase I/II randomized study evaluating hydroxyurea with or without clotrimazole in patients with si…
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CLINICAL_TRIALS research · 2015-03-25Clinical Trial Update: Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes [NA]
A clinical trial examining clotrimazole and hydroxyurea in patients with sickle cell syndromes has completed.
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Effects of HQK-1001 in Patients With Sickle Cell Disease [Phase 2]
A Phase 2 clinical trial evaluating HQK-1001 in patients with sickle cell disease has been terminated.
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation [NA]
Clinical trial update indicating termination of an Alefacept plus allogeneic hematopoietic stem cell transplantation study, with results pos…
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CLINICAL_TRIALS research · 2015-03-05Clinical Trial Update: The Feasibility of Text Messaging to Assess Secondhand Smoke Exposure Among Youngsters With Cancer or Sickle Cell Disease
This completed study assessed whether text messaging can feasibly measure secondhand smoke exposure in children with cancer or sickle cell d…
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CLINICAL_TRIALS research · 2015-03-05Clinical Trial Update: Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting
A completed pediatric trial update examining parental willingness to enroll children in tobacco-related studies, sponsored by St. Jude Child…
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: Improving Emergency Department Management of Adults With Sickle Cell Disease
This clinical trial update notes the completion of a study aimed at improving emergency department management for adults with sickle cell di…
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CLINICAL_TRIALS trial_result · 2015-02-16Clinical Trial Update: Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates Equally [Phase 3]
Phase 3 clinical trial comparing opioid management options for pain in sickle cell disease with results completed and posted.
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CLINICAL_TRIALS trial_result · 2015-02-16Clinical Trial Update: Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo [Phase 2]
A Phase 2 trial comparing prophylactic-dose low-molecular-weight heparin to placebo in hospitalized sickle cell patients experiencing a pain…
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CLINICAL_TRIALS trial_result · 2015-01-22Clinical Trial Update: Study of Propranolol as Anti-Adhesive Therapy in Sickle Cell Disease (SCD) [Phase 2]
A Phase 2 clinical trial evaluated propranolol as an anti-adhesive therapy for sickle cell disease and has completed with results posted in …
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CLINICAL_TRIALS withdrawal · 2014-12-23Clinical Trial Update: Assessment of Opioid Analgesia in Sickle Cell [Phase 4]
A Phase 4 clinical trial assessing opioid analgesia in sickle cell disease was withdrawn.
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CLINICAL_TRIALS trial_result · 2014-12-12Clinical Trial Update: Pharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell Anemia [Phase 1]
This Phase 1 clinical trial update reports pharmacokinetic data for liquid hydroxyurea in pediatric patients with sickle cell anemia.
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CLINICAL_TRIALS trial_result · 2014-12-04Clinical Trial Update: Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children [Phase 2]
Phase 2 trial evaluated inhaled nitric oxide for treating Acute Chest Syndrome in children with Sickle Cell Disease; the study status is com…
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Study of SANGUINATE™ Versus Hydroxyurea in Sickle Cell Disease (SCD) Patients [Phase 1]
Phase 1 clinical trial comparing SANGUINATE to hydroxyurea in patients with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease [Phase 1]
A Phase 1 clinical trial update reporting completion of a study quantifying lung disease and pulmonary hypertension in children with sickle …
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CLINICAL_TRIALS trial_result · 2014-11-20Clinical Trial Update: Treatment of Sickle Cell Anemia With Stem Cell Transplant [NA]
This clinical trial update reports that a stem cell transplant study for sickle cell diseases was terminated, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-10-30Clinical Trial Update: Lidocaine 5% Plasters (Versatis® 5%) in Pediatric Neuropathic Pains and Vasoocclusive Sickle Cell Crisis Pains [Phase 2]
Phase 2 clinical trial of lidocaine 5% plaster (Versatis) in pediatric neuropathic pain and vaso-occlusive pain in sickle cell disease has c…
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CLINICAL_TRIALS trial_result · 2014-10-28Clinical Trial Update: Microvascular and Cardiac Dysfunction in Paroxysmal Nocturnal Hemoglobinuria and Sickle Cell Disease
This update summarizes a completed clinical trial investigating microvascular and cardiac dysfunction in Paroxysmal Nocturnal Hemoglobinuria…
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CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: Cognitive Rehabilitation in Sickle Cell Disease [NA]
The document reports that the clinical trial examining cognitive rehabilitation for individuals with sickle cell disease and cognitive impai…
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CLINICAL_TRIALS trial_result · 2014-08-13Clinical Trial Update: Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders [Phase 1]
Clinical trial update on reduced intensity conditioning for umbilical cord blood transplantation in pediatric patients with non-malignant di…
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CLINICAL_TRIALS trial_result · 2014-08-06Clinical Trial Update: Systematic Psychological and Medical Care for Children With SCD
The clinical trial evaluating systematic psychological and medical care for children with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2014-07-14Clinical Trial Update: Evaluation of Spectra Optia Red Blood Cell Exchange in Sickle Cell Patients [NA]
A completed clinical trial evaluating Spectra Optia Red Blood Cell Exchange in patients with Sickle Cell Disease; results were posted in 201…
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CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: Serum Brain Natriuretic Peptide Levels and Pulmonary Hypertension in Pediatric Sickle Cell Patients
Completed clinical trial examining serum brain natriuretic peptide levels in pediatric patients with sickle cell disease and pulmonary hyper…
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CLINICAL_TRIALS research · 2014-06-24Clinical Trial Update: Adolescent, Caregiver, and Young Adult Perspectives of the Transition From Pediatric to Adult Care for Sickle Cell Disease: A Preliminary Evaluation of the Sickle Cell Disease Transition Program
This study reports a preliminary evaluation of St. Jude Children’s Research Hospital’s Sickle Cell Disease Transition Program, examining ado…
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CLINICAL_TRIALS trial_result · 2014-06-18Clinical Trial Update: Trial of Zileuton CR in Children and Adults With Sickle Cell Disease [Phase 1]
This clinical trial update reports completion of a Phase 1 study evaluating sustained-release zileuton (Zileuton CR) in children and adults …