Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Outcomes of Vaso-occlusive Crisis in Pediatric Sickle Cell Disease
The update describes outcomes of vaso-occlusive crisis in pediatric sickle cell disease from the clinical trial NCT07200869, which is curren…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: A Research Study of the Effect of Etavopivat on Other Drugs in Healthy Participants [Phase 1]
Completed Phase 1 study evaluating the effect of etavopivat on other drugs in healthy participants, sponsored by Novo Nordisk A/S.
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Daily Vitamin D for Sickle-cell Respiratory Complications [Phase 2]
Phase 2 trial evaluating daily vitamin D for sickle cell–related respiratory complications has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease [Phase 1]
Phase 1 safety update on using Plerixafor to mobilize blood stem cells in patients with Sickle Cell Disease; the study is active but not rec…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Observational Prospective Study Measuring the Impact of the Use of a Hypnotic Script Associated With Virtual Reality on the Pain of the Child's Sickle Cell During a Vaso-occlusive Crisis [NA]
This is an observational prospective study evaluating whether a hypnotic script combined with virtual reality reduces pain in pediatric sick…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease [Phase 1, Phase 2]
This update reports the completion of a Phase 1/2 study evaluating the safety, tolerability, and efficacy of BIVV003 in autologous hematopoi…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Prognostic Factors of Acute Splenic Sequestration [NA]
A completed clinical trial update investigating prognostic factors for acute splenic sequestration in sickle cell disease.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Assessment of Tolerance of Mobilizing Peripheral Hematopoietic Stem Cells by Plerixafor in Sickle Cell Patients [Phase 1, Phase 2]
Phase 1/2 trial assessing tolerance of mobilizing peripheral hematopoietic stem cells using plerixafor in patients with sickle cell disease …
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease [Phase 2]
This clinical trial update notes the completion of a Phase 2 study evaluating HLA haploidentical bone marrow transplant in patients with sev…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD). [Phase 1]
Phase 1 study evaluating safety, pharmacokinetics, pharmacodynamics, and efficacy of Crovalimab for the management of acute uncomplicated va…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Sickle Cell Disease (SCD) Bone Pain Study [NA]
Clinical trial update from UC Davis on sickle cell disease-related bone pain; the study is active but not recruiting, with results posted in…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: EXTEND EXpanding Treatment for Existing Neurological Disease [Phase 2]
A Phase 2 clinical trial evaluating an extended treatment approach for existing neurological disease in sickle cell anemia has completed.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia [NA]
The SACRED A trial, a prospective study aimed at reducing stroke in children with sickle cell disease, has completed.
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: Sickle Cell Disease, Hemechip
A completed clinical trial evaluating Hemechip for sickle cell disease conducted at University Hospitals Cleveland Medical Center.
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease [Phase 2]
Phase 2 pediatric trial evaluating GBT440 (voxelotor) for sickle cell disease was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease [Phase 2, Phase 3]
A safety and efficacy study of CTX001 in subjects with severe Sickle Cell Disease has completed Phase 2 and Phase 3 trials.
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD) [Phase 1]
Phase 1 trial update describes a combination of Motixafortide and Natalizumab to mobilize CD34+ hematopoietic stem cells for gene therapies …
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Sex Hormones and Inflammatory Biomarkers in Patients With Sickle Cell Disease
A completed clinical trial evaluating the relationship between sex hormones and inflammatory biomarkers in patients with sickle cell disease…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell Trait
A completed clinical trial update from NHLBI evaluating biomarkers related to venous thrombosis in people with sickle cell disease and sickl…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients With Sickle Cell Disease (SCD)
This completed clinical trial update describes using near-infrared spectroscopy to assess muscle physiology, tissue oxygenation, and blood f…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial [Phase 3]
Phase 3 STArT trial evaluating arginine therapy for sickle cell disease has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Full Assessment of Clinical Transfusion Support
Clinical trial update noting the completion of a study on transfusion support in sickle cell anemia, with attention to malaria parasitaemia.
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions [NA]
Completed clinical trial results have been posted for the Peer i-Coaching program, evaluating activated self-management optimization in adol…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: Study of MGTA-145 and Plerixafor in Patients With Sickle Cell Disease [Phase 2]
A Phase 2 trial evaluating MGTA-145 in combination with Plerixafor for sickle cell disease was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients [Phase 2]
Phase 2 study evaluating dose confirmation and safety of crizanlizumab in pediatric sickle cell disease patients; results have been posted.