Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: A Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese Participants [Phase 1]
Phase 1 study evaluating a single dose of etavopivat in healthy Chinese participants has completed.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Development and Adaptation of I-STRONG for SCD [NA]
Emory University reports that the development and adaptation of I-STRONG for sickle cell disease has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease [NA]
This completed clinical trial, sponsored by Hospices Civils de Lyon, studied muscle function and its biological and physiological determinan…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Function [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating non-myeloablative haploidentical hematopoietic cell transplantation for sickle cell disease, including…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Stem Cell Gene Therapy for Sickle Cell Disease [Phase 1, Phase 2]
An update on a Phase 1/Phase 2 stem cell gene therapy trial for sickle cell disease led by Donald B. Kohn; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease [Phase 3]
A Phase 3 study evaluating the long-term safety of inclacumab in sickle cell disease was terminated.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease [Phase 2]
A Phase 2 study of etavopivat in patients with sickle cell disease and thalassemia has completed.
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: The Effect of Voxelotor on Cerebral Hemodynamic Response in Children With Sickle Cell Anemia [Phase 2]
Phase 2 trial evaluating voxelotor for cerebral hemodynamic response in children with sickle cell disease has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Lipid Balance in Adult Sickle Cell Patients [NA]
This clinical trial update notes an ongoing study evaluating lipid balance in adults with sickle cell disease and dyslipidemia, currently ac…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Cohort Study of Sickle Cell Patients Evaluating Analgesic Strategies and Their Consequences
A completed cohort study in patients with Sickle Cell Disease evaluating various analgesic strategies and their consequences.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET [Phase 2]
A Phase 2 trial at St. Jude is investigating the relationship between abnormal myocardial perfusion and diastolic dysfunction in sickle cell…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises [Phase 3]
Pfizer's inclacumab in sickle cell disease patients experiencing vaso-occlusive crises has completed Phase 3 testing. Results have been post…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Oral Ketamine for Treatment of Vaso-Occlusive Pain [Phase 3]
This clinical trial update reports a Phase 3 study of oral ketamine for vaso-occlusive crisis pain in sickle cell disease, currently recruit…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Oxygen Therapy and Pregnancy in Sickle Cell Disease [Phase 3]
A Phase 3 trial assessing oxygen therapy for pregnant people with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD) [NA]
A clinical trial update reports on the feasibility and preliminary efficacy of Acceptance and Commitment Therapy (ACT) for sleep disturbance…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031 [Phase 3]
A Phase 3 extension study evaluating long-term treatment with voxelotor in participants who completed the prior study in sickle cell disease…
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CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: Open-Label Extension of Voxelotor [Phase 3]
Open-label extension of voxelotor in sickle cell disease (Phase 3) has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.
Sangamo Therapeutics provides an update on long-term follow-up for sickle cell disease and beta-thalassemia subjects previously treated with…
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CLINICAL_TRIALS trial_result · 2025-10-28Clinical Trial Update: The Feasibility of the PAINReportIt Guided Relaxation Intervention-INPATIENT [NA]
A completed inpatient feasibility study evaluating the PAINReportIt guided relaxation intervention for pain management in sickle cell diseas…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell Disease [Phase 2]
Phase 2 clinical trial update evaluating the pharmacokinetics, pharmacodynamics, and safety of Epeleuton in patients with Sickle Cell Diseas…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Gerofit Exercise Intervention for Older Adults With Sickle Cell Disease (SICKLE-FIT Study) [NA]
The SICKLE-FIT trial, evaluating the Gerofit exercise intervention for older adults with sickle cell disease, has completed.
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: A Research Study of the Effect of Food on Etavopivat in Healthy Participants [Phase 1]
Phase 1 study assessing the effect of food on Etavopivat in healthy participants has been completed; the update focuses on pharmacokinetic i…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: Interest of Famotidine in Children With Sickle Cell Disease [Phase 2, Phase 3]
Completed Phase 2/Phase 3 clinical trial evaluating famotidine for sickle cell disease in children.
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Long-term Follow-up (LTFU) of Patients Treated With Genome-edited Autologous Hematopoietic Stem and Progenitor Cells (HSPC) [Phase 1]
This clinical trial update provides long-term follow-up results for sickle cell disease patients treated with genome-edited autologous hemat…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Adding Azathioprine/Hydroxyurea Preconditioning to Alemtuzumab/TBI to Reduce Risk of Graft Failure in MSD HSCT in Adult SCD Patients
This clinical trial update notes the addition of azathioprine and hydroxyurea preconditioning to an alemtuzumab/TBI regimen in matched-sibli…