Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Exercise in Child Health [NA]
A University of California, Irvine-sponsored clinical trial is recruiting to evaluate exercise in child health, including cystic fibrosis, s…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Natural History of Sickle Cell Disease
This clinical trial update describes a natural history study of sickle cell disease related to pain crisis, and it is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease [Phase 3]
Phase 3 clinical trial update for CTX001 (exagamglogene autotemcel) assessing a single dose in transfusion-dependent beta-thalassemia and se…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana [NA]
This clinical trial update notes that a multi-disciplinary sickle cell disease obstetrics care program in Ghana is currently recruiting part…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Integrating Point of Care Testing (POCT) For Newborn Screening and Early Care for Sickle Cell Disease in Yopougon, Côte d'Ivoire [Phase 4]
A Phase 4 study in Yopougon, Côte d'Ivoire aims to integrate point-of-care testing into newborn screening and early care for sickle cell dis…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease [NA]
A sponsored clinical trial by Ohio State University is recruiting adults with sickle cell disease to test delivering evidence-based guidelin…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Phase 2/3 Study in Adult and Adolescent Participants With SCD [Phase 2, Phase 3]
Pfizer is conducting a Phase 2/3 clinical trial in adults and adolescents with Sickle Cell Disease, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Inflammation, Platelets and Sickle Cell Disease
This entry provides an update on an ongoing clinical trial exploring inflammation, platelet activation, and thromboinflammation in sickle ce…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Efficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive Crisis [NA]
A clinical trial is comparing liberal versus restricted intravenous fluid strategies to manage sickle cell disease-related vaso-occlusive cr…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease [Phase 2]
A Phase 2 trial is evaluating losartan for diffuse myocardial fibrosis in patients with sickle cell disease and is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease [Phase 1, Phase 2]
This clinical trial update describes ongoing Phase 1 and Phase 2 studies evaluating BMS-986470 in healthy volunteers and participants with s…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease
This clinical trial update shows that researchers are recruiting to study how PKLR genetic variants relate to red blood cell enzyme activiti…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial [Phase 2]
A Phase 2 trial to evaluate zinc supplementation in sickle cell disease as a precursor to the Think Zinc for Bones Trial, currently recruiti…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Allo HSCT for High Risk Hemoglobinopathies [Phase 2]
Phase 2 clinical trial update evaluating allogeneic hematopoietic stem cell transplantation for high-risk hemoglobinopathies, including sick…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Telemedicine for Children With Sickle Cell Disease [NA]
This document reports an active, not-recruiting clinical trial from Indiana University evaluating telemedicine for children with sickle cell…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia [Phase 1, Phase 2]
NHLBI-sponsored clinical trial update describes adding JSP191, a C-kit antibody, to a nonmyeloablative hematopoietic cell transplantation re…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating autologous CD34+ hematopoietic stem cells gene-corrected from HbS to HbA to treat severe sickle cell dis…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease [Phase 2]
A Phase 2 study aims to minimize transplant toxicity in HLA-identical sibling donor transplantation for children with sickle cell disease; t…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive Care [NA]
A clinical trial update announcing recruitment for a study on morphine clearance and glomerular filtration in sickle cell crisis patients in…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults [Phase 2]
The document notes a Phase 2 clinical trial evaluating sub-dissociative dose ketamine for vaso-occlusive pain episodes in children and young…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Optimal Timing of Ketamine Initiation for SCD Pain [Phase 3]
Phase 3 trial on ketamine initiation timing for pain management in sickle cell disease is not yet recruiting, indicating an upcoming study r…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Blood Sampling for Research Related to Sickle Cell Disease
NIDDK-sponsored clinical trial on blood sampling for research related to sickle cell disease is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Blood Stem Cell Transplant for Sickle Cell Disease [Phase 1]
Phase 1 clinical trial update on a blood stem cell transplant for sickle cell disease; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Stroke Prevention in Nigeria 2 Trial [Phase 4]
A Phase 4 clinical trial in Nigeria led by Vanderbilt University Medical Center is evaluating stroke prevention in people with sickle cell d…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Efficacy Safety Study of Gene Therapy for Sickle Cell DiseaseSCD Using Autologous CD34+ Cells Transduced ex Vivo, Carrying a Corrected Globin Gene and a Silencing RNA. [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating an autologous CD34+ stem cell gene therapy with a corrected globin gene and silencing RNA for sickl…